Geriatrics News and Research

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Platelet-rich plasma may enhance ovarian rejuvenation and improve egg quality in women

A new research paper was published in Aging (Aging-US) on February 18, 2025, Volume 17, Issue 2, titled "Transcriptomic landscape of cumulus cells from patients <38 years old with a history of poor ovarian response (POR) treated with platelet-rich plasma (PRP)."

10 Mar 2025

Mount Sinai Hospital named top hospital in New York State for three consecutive years

For the third straight year, The Mount Sinai Hospital is ranked the top hospital in New York State on Newsweek/Statista's "World's Best Hospitals" list for 2025.

10 Mar 2025

Long-term NSAID use may lower dementia risk

Long-term NSAID use reduces dementia risk, particularly in those without the APOE-ε4 gene, highlighting the importance of sustained anti-inflammatory treatment over dosage levels.

9 Mar 2025

Study links environmental chemical exposures to faster biological aging

A new research paper was published in Aging (Aging-US) on February 11, 2025, Volume 17, Issue 2, titled "Exposome-wide association study of environmental chemical exposures and epigenetic aging in the national health and nutrition examination survey."

5 Mar 2025

Long-term NSAID use linked to lower dementia risk

Past research has suggested that inflammation may contribute to the development and progression of dementia and that non-steroidal anti-inflammatory (NSAID) medications may help protect against dementia due to their anti-inflammatory effects.

5 Mar 2025

Novel strategy targets beta cell dysfunction in type 2 diabetes

Researchers from the Icahn School of Medicine at Mount Sinai in New York have discovered a novel approach to protecting insulin-producing beta cells from the damaging effects of glucolipotoxicity-a harmful condition linked to the progression of type 2 diabetes (T2D).

4 Mar 2025

Research identifies iron as crucial driver of stroke-related cell death processes

Ischemic stroke continues to rank among the top causes of death and long-term disability globally. While advances in acute treatments like clot retrieval and thrombolysis have improved outcomes, the challenge of managing reperfusion injury—a phase when restored blood flow can ironically harm brain tissue—persists.

4 Mar 2025

Discovery of stable genes offers insights into aging and longevity

A new research paper was published in Aging (Aging-US) on January 27, 2025, in Volume 17, Issue 1, titled "Age-invariant genes: multi-tissue identification and characterization of murine reference genes."

26 Feb 2025

Study finds higher odds of hypothyroidism among South Asian immigrants in Canada

A new study published this week in Archives of Gerontology and Geriatrics Plus found that 10% of South Asian immigrants aged 45 and older in Canada had hypothyroidism.

25 Feb 2025

Study uncovers pathway behind age-related degeneration of eye glands

A team led by Mount Sinai researchers has identified stem cell populations and mechanisms underlying age-related degeneration in glands that are vital to eye function.

24 Feb 2025

Unveiling the role of FAM20C in disease and cancer treatment

A new review published in Genes & Diseases explores the multifaceted role of FAM20C, a Golgi protein kinase, in disease progression.

23 Feb 2025

New frailty index helps predict hospitalization and death risks in older adults

Investigators at Mass General Brigham have developed a tool that can identify older adults at increased risk of emergency healthcare needs, rehospitalization or death.

21 Feb 2025

Standardized goals of care note enhances communication in healthcare

It is important that a healthcare team is aware of and understands a patient's goals of care, both medical and personal.

19 Feb 2025

Inflammation and metabolic syndrome contribute to prostate enlargement in aging men

A new research paper was published by Aging (Aging-US) on January 6, 2025, in Volume 17, Issue 1, titled "The profile of oxidative stress markers (arachidonic and linoleic acid derivatives) in patients with benign prostatic hyperplasia in relation to metabolic syndrome."

19 Feb 2025

SPRINT analysis supports lower blood pressure targets for older adults

Results from the Systolic Blood Pressure Intervention Trial (SPRINT) have supported lower blood pressure targets among community-dwelling older adults with hypertension to reduce the risk of cardiovascular disease and early death, but intensive blood pressure lowering can also increase risks of developing acute kidney injury and experiencing dangerously low blood pressure.

19 Feb 2025

Senolytic agent ABT-263 mitigates GI cancer risk after radiation exposure

A new research paper was published by Aging (Aging-US) on January 8, 2025, in Volume 17, Issue 1, titled "Senolytic agent ABT-263 mitigates low- and high-LET radiation-induced gastrointestinal cancer development in Apc1638N/+ mice."

18 Feb 2025

New balance test could help predict falls in older adults

The scenario is common. An elderly person seems to be in good health until one day they suffer a fall and from then on their quality of life begins to deteriorate.

12 Feb 2025

Research explores DNA methylation clock accuracy across tissues

A new research paper was published in Aging (Aging-US) on January 3, 2025, in Volume 17, Issue 1, titled "Characterization of DNA methylation clock algorithms applied to diverse tissue types."

12 Feb 2025

Physical activity improves sleep quality in older adults during social isolation

A new research paper was published in Aging (Aging-US) on January 15, 2025, in Volume 17, Issue 1, titled "Association between physical activity practice and sleep quality of older people in social isolation during the COVID-19 pandemic and Health Guidelines and future studies for the post-COVID period: a systematic review."

11 Feb 2025

Study shows improvement in disability-free life for older Americans

A sizeable improvement was found in the prevalence of American adults aged 65 and older without disabilities -- including memory, hearing, visual, and functional disabilities or limitations in activities of daily living -- according to a new nationally representative study published online in the Archives of Gerontology and Geriatrics Plus found.

11 Feb 2025