Hemorrhagic Fever News and Research

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Viral hemorrhagic fevers (VHFs) refer to a group of illnesses that are caused by several distinct families of viruses. In general, the term "viral hemorrhagic fever" is used to describe a severe multisystem syndrome (multisystem in that multiple organ systems in the body are affected). Characteristically, the overall vascular system is damaged, and the body's ability to regulate itself is impaired. These symptoms are often accompanied by hemorrhage (bleeding); however, the bleeding is itself rarely life-threatening. While some types of hemorrhagic fever viruses can cause relatively mild illnesses, many of these viruses cause severe, life-threatening disease.

Mitochondrial rewiring may explain why orthoflaviviruses harm humans but persist in mosquitoes

Orthoflaviviruses reshape mitochondrial structure, metabolism, redox signaling, and quality control differently across human and mosquito models, helping explain their contrasting infection outcomes. The review highlights mitochondrial pathways that may support acute cellular damage in vertebrates but persistent, non-lethal infection in mosquitoes, pointing to potential antiviral targets.

12 Aug 2026

Heavy rainfall and flooding raise infectious disease risks across Europe

A rapid review of 14 studies found that heavy rainfall and flooding were associated with outbreaks and increased incidence of several infectious diseases across Europe, particularly campylobacteriosis and leptospirosis. The authors highlighted major evidence gaps and called for stronger One Health surveillance, public health communication, sanitation, and flood-response planning.

10 Aug 2026

Tick-borne viruses show concerning potential for future pandemics

A study led by a University of California, Riverside biomedical scientist shows how a family of tick-borne viruses known as orthonairoviruses can evade immune defenses, offering important insights into emerging infectious disease threats and the potential pandemic risk posed by these viruses.

14 Jul 2026

Researchers uncover how emerging tick borne nairoviruses evade human immunity

Warmer temperatures bring out ticks that spread diseases such as Lyme disease and Rocky Mountain spotted fever.

14 Jul 2026

Korea University College of Medicine selected as the lead institution for hantavirus vaccine development project

The Vaccine Innovation Center at Korea University College of Medicine has been selected by the Korea Disease Control and Prevention Agency (KDCA) as the lead institution for a national hantavirus vaccine development project.

6 Jul 2026

Decades of research reveal surprising secrets about hantavirus evolution

Thirty years ago, it was our common sense understanding that hantavirus does not and perhaps cannot spread from human to human. It turns out there is one exception: a strain called the Andes virus.

2 Jul 2026

Scientists discover 70 existing drugs that block deadly hantavirus infections

Researchers screened over 5,000 compounds and successfully pinpointed 70 existing drugs, including unexpected beta-lactam antibiotics, that effectively suppress Puumala orthohantavirus infection in human cells. This milestone drug-repurposing study provides an immediate, fast-tracked pipeline for developing the first approved treatments against life-threatening hantavirus diseases.

28 Jun 2026

How clinicians can identify and manage Ebola, hantavirus

Two deadly infectious diseases, Ebola https://www.cmaj.ca/lookup/doi/10.1503/cmaj.260834 and hantavirus https://www.cmaj.ca/lookup/doi/10.1503/cmaj.260789, have made headlines in recent weeks as they pose serious threats to public health.

22 Jun 2026

New AI tools identify potential drugs for rare Ebola virus

Recent advances in artificial intelligence have enabled Southwest Research Institute (SwRI) to identify nearly two dozen antiviral compounds that could potentially treat a rare species of Ebola virus (Bundibugyo virus) currently affecting the Democratic Republic of Congo.

26 May 2026

New vaccine approach targets broad protection against arenavirus infections

Scientists at La Jolla Institute for Immunology (LJI) have discovered that combining key vaccine ingredients could give the body the tools it needs to fight the entire family of arenaviruses with a single vaccine.

21 May 2026

Health experts outline symptoms and risks of shipboard hantavirus

It's one of the cruisegoer's biggest fears: a contagious disease outbreak at sea.

18 May 2026

Hantavirus scare on cruise ship prompts WHO response

Hantavirus infections among cruise ship passengers have sparked a global health response, highlighting the need for effective outbreak management strategies.

7 May 2026

New nanoparticle vaccines show promise against multiple deadly filoviruses

Filoviruses get their name from the Latin word "filum," meaning thread-a reference to their long, filamentous shape. This virus family contains some of the most dangerous pathogens known to science, including Ebola, Sudan, Bundibugyo and Marburg viruses.

18 Dec 2025

Global Virus Network outlines priorities as Marburg virus emerges in Ethiopia

The Global Virus Network (GVN), a coalition of leading human and animal virologists in more than 40 countries dedicated to advancing pandemic preparedness through research, education and training, and global health solutions, today issued a statement on the newly confirmed outbreak of Marburg virus disease (MVD) in southern Ethiopia.

27 Nov 2025

Promising long-term vaccine for Crimean-Congo hemorrhagic fever developed

Crimean-Congo hemorrhagic fever (CCHF) is one of the world's most dangerous yet overlooked infectious diseases.

22 Nov 2025

Research shows Sudan Ebola's lasting impact and potential for mother-to-child transmission

More than half of survivors of the Sudan Ebola virus still suffer serious health problems two years post-infection and the virus can persist in semen and breast milk for months after recovery, according to the first study examining the virus's long-term effects.

3 Oct 2025

NIH awards $3.4 million to support research on Crimean-Congo hemorrhagic fever virus

Crimean-Congo hemorrhagic fever virus, or CCHFV, is a biosafety level 4 pathogen and a Category A bioterrorism agent, causing severe viral hemorrhagic fever with mortality rates reaching up to 40%.

24 Sep 2025

GP38 identified as key viral toxin and vaccine target in Crimean-Congo hemorrhagic fever virus research

A recent study published in Science Translational Medicine involving scientists from the U.S. Army Medical Research Institute of Infectious Diseases in collaboration with scientists from the Albert Einstein College of Medicine and the University of California-Berkeley have advanced discoveries surrounding the viral glycoprotein GP38 expressed by the Crimean-Congo hemorrhagic fever virus (CCHFV).

8 Apr 2025

Clinical trial of vaccine candidate to prevent Lassa fever begins enrollment

A National Institutes of Health (NIH)-sponsored clinical trial of a candidate vaccine to prevent Lassa fever has begun enrolling participants at the University of Maryland School of Medicine, Baltimore.

17 Mar 2025

New biosensor technology could revolutionize mpox diagnosis

A new variant of human mpox has claimed the lives of approximately 5% of people with reported infections in the Democratic Republic of the Congo since 2023, many of them children. Since then, it has spread to several other countries.

14 Nov 2024