Cell Biology

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Genentech researchers uncover epigenetic regulator of pancreatic cancer cells

Genentech researchers have identified an enzyme that shifts pancreatic cancer cells to a more aggressive, drug-resistant state by epigenetically modifying the cells' chromatin.

11 Dec 2017

Live-cell microscopy reveals internal forces that direct cell migration

Two new studies conducted at the Marine Biological Laboratory (MBL) indicate the way by which cells react to internal forces when they orient, gain traction, and migrate in a particular direction.

11 Dec 2017

Phasefocus™ appoints Chinese distributor as part of Asia expansion

Phasefocus continues to increase its global international profile with the appointment of Nuohai Life Sciences as the company’s exclusive distributor for mainland China, Hong Kong and Macau.

From Phase Focus Limited 11 Dec 2017

Researchers establish function of long RNA strands in skin development and disease

Researchers have found out how long pieces of RNA called “long non-coding RNAs” (LncRNAs) work in skin cells to modulate connective tissue proteins such as collagen, potentially laying the foundations for new skin repair therapies.

7 Dec 2017

Scientists introduce polyproline as effective cryoprotectant for monolayers of cells

Nature has evolved sugars, amino acids, and special antifreeze proteins as cryoprotectants. People use organic solvents and synthetic polymers as additives to prevent cell cultures from freezing damage.

7 Dec 2017

Biological Applications of AFM

An interview with Samuel Lesko, European Applications Manager, Bruker Nano Surfaces conducted by April Cashin-Garbutt, MA (Cantab).

From Bruker Nano Surfaces and Metrology 5 Dec 2017

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

There's a continued drive towards making in vitro assays ever more translational towards in vivo models and ultimately the clinic. This ties in with the resurgence of phenotypic screening and is a response to the perceived poor translation of the traditional simple cell-based assays, often developed to study just single protein targets.

From Sartorius 5 Dec 2017

Research shows how cells rebuild nucleus, organize genome after division

University of Bristol research has revealed how cells rebuild their nucleus and organise their genome when they divide - a discovery which could have major implications for understanding cancer and degeneration.

4 Dec 2017

USC researchers propose rules for making ribs

Scientists from the USC Stem Cell lab of Francesca Mariani recently shared a recipe for ribs, and it doesn't even require barbecue sauce.

29 Nov 2017

New discovery could speed up production of cells for studying diseases

Scientists have made a key discovery that could speed up the production of cells in the lab for studying diseases such as multiple sclerosis and Parkinson's disease.

28 Nov 2017

Newcastle scientists develop new technique that revolutionizes cell culture

A technique which revolutionizes cell culture by allowing the continuous production and collection of cells, has been developed by scientists at Newcastle University.

28 Nov 2017

Virus Painting, Lipids and Single Particle Charge

Various viral infections still pose a great threat to human and animal health. A wide range of viral species are surrounded by a lipid shell, the envelope, containing viral and cellular proteins.

From Izon Science 27 Nov 2017

3D folding of DNA during cardiomyocyte differentiation provides vital epigenetic mechanisms, study says

A new study conducted at the University of Freiburg suggests that three-dimensional (3D) folding of the DNA reorganizes itself during differentiation of pluripotent stem cells to cardiomyocytes.

22 Nov 2017

Study finds specific tumor environment that stimulates cancer cells to metastasize

A new study, conducted by a team of researchers from the University of California, San Diego, has identified how the environment surrounding a tumor can stimulate metastatic behavior in the individual cancer cells. Researchers found that the tumor cells activate a particular set of genes and begin to form blood vessel-like structures when they are confined in a densely packed environment.

22 Nov 2017

Scientists develop new approach to combating antibiotic resistance

A team of researchers have developed a way of preventing the transfer of antibiotic resistance genes between bacteria.

22 Nov 2017

New mechanism in cancer cells to disarm attacking immune cells, study reveals

A new study, published in the Journal of Clinical Investigation, identified a substance Gdf-15, which is secreted by pancreatic cancer cells and shields cancerous cells from attack by immune cells known as macrophages.

21 Nov 2017

Probing living cells with AFM

An interview with Prof. David Alsteens, Université Catholique de Louvain conducted by April Cashin-Garbutt, MA (Cantab).

From Bruker Nano Surfaces and Metrology 21 Nov 2017

Applying AFM to study the viscoelastic properties of cells

An interview with Prof. Manfred Radmacher, Universität Bremen conducted by April Cashin-Garbutt, MA (Cantab).

From Bruker Nano Surfaces and Metrology 16 Nov 2017

Scientists find key that allows neural differentiation of microRNA-deficient pluripotent stem cells

The more than 200 different types of human cells have the same DNA but express different ensembles of genes. Each cell type was derived from embryonic stem cells, which are called pluripotent stem cells because they can differentiate to all those different cell fates.

15 Nov 2017

Tulane professor wins Department of Defense grant for research into arteriovenous malformations

Tulane University's Stryder Meadows, a cell and molecular biology professor, received a $1.7 million grant from the Department of Defense to study how arteriovenous malformations (AVM), which are defects in arteries, veins and capillaries, form Hereditary Hemorrhagic Telangiectasia (HHT), a genetic disorder that affects about 1 in 5,000 people.

14 Nov 2017

Cell Biology

Genentech researchers uncover epigenetic regulator of pancreatic cancer cells

Live-cell microscopy reveals internal forces that direct cell migration

Phasefocus™ appoints Chinese distributor as part of Asia expansion

Researchers establish function of long RNA strands in skin development and disease

Scientists introduce polyproline as effective cryoprotectant for monolayers of cells

Biological Applications of AFM

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

Research shows how cells rebuild nucleus, organize genome after division

USC researchers propose rules for making ribs

New discovery could speed up production of cells for studying diseases

Newcastle scientists develop new technique that revolutionizes cell culture

Virus Painting, Lipids and Single Particle Charge

3D folding of DNA during cardiomyocyte differentiation provides vital epigenetic mechanisms, study says

Study finds specific tumor environment that stimulates cancer cells to metastasize

Scientists develop new approach to combating antibiotic resistance

New mechanism in cancer cells to disarm attacking immune cells, study reveals

Probing living cells with AFM

Applying AFM to study the viscoelastic properties of cells

Scientists find key that allows neural differentiation of microRNA-deficient pluripotent stem cells

Tulane professor wins Department of Defense grant for research into arteriovenous malformations

Leveraging the Radian ASAP in standard casework

A journey through science, software, and innovation: Insights from the Bruker software team

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

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