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Recombinant zoster vaccine well tolerated by patients with inflammatory RMD

Herpes zoster (HZ) is common in older people, with a lifetime risk of 25%. The main risk factors are advanced age and immunosuppression. People with a rheumatic and musculoskeletal disease have an overall higher risk for shingles.

11 Jun 2025

Legal environment shapes doctors’ preferences for assisted dying

When it comes to advanced cancer or Alzheimer's disease, over half of doctors would consider assisted dying for themselves, but preferences seem to vary according to their jurisdiction's legislation on euthanasia, reveal the results of an international survey, published online in the Journal of Medical Ethics.

11 Jun 2025

Waist-to-height ratio found to predict liver damage better than BMI

Excess fat mass estimated by waist circumference-to-height ratio predicts the risk of liver damage better than body mass index (BMI) estimated obesity, a new study shows.

11 Jun 2025

Unexpected protein production in immune cells may fuel gut inflammation

Scientists have discovered that certain immune cells — called neutrophils — can start making a protein called DUOX2 that they usually do not produce.

11 Jun 2025

New cancer vaccine shows promise against deadly pancreatic tumors

Pancreatic cancer has a five-year survival rate of just 13%, making it the deadliest cancer, according to the American Cancer Society.

11 Jun 2025

CHAF1B drives lung squamous cell carcinoma progression by repressing SETD7

CHAF1B, a histone chaperone component of the chromatin assembly factor-1 complex, is overexpressed in multiple cancers and linked to tumor progression, but its role in lung squamous-cell carcinoma (LUSC) remained unclear.

11 Jun 2025

Rethinking dementia through the lens of sensory changes

Memory problems have long been considered the primary hallmark of dementia, but a team of researchers is now challenging this view. They argue that changes in sensory perception – from vision to balance – may be equally important indicators that many healthcare providers are currently missing.

11 Jun 2025

AMA endorses resolution to expand access to anti-obesity medications

The American Medical Association (AMA) House of Delegates today passed the Endocrine Society's resolution to improve access to anti-obesity medications.

11 Jun 2025

John Oldham redefines the landscape of personality disorders

In a comprehensive Genomic Press Interview published today in Brain Medicine, John M. Oldham, MD, MS, one of psychiatry's most influential architects of personality disorder theory, traces his remarkable journey from frontier medicine roots in Oklahoma to revolutionizing how mental health professionals understand and diagnose personality pathology.

11 Jun 2025

Uncovering the genetic link between type 2 diabetes and brain structure

Type 2 diabetes mellitus (T2DM) is a highly prevalent metabolic disorder worldwide. Beyond glucose dysregulation, it exerts significant effects on the central nervous system.

11 Jun 2025

Modified DASH diet shows blood pressure benefits for adults with diabetes

An estimated 38.1 million adults in the United States had diagnosed diabetes in 2021, according to the Centers for Disease Control and Prevention.

11 Jun 2025

Large cohort study reassures on mRNA vaccine safety for early pregnancies

A large prospective cohort study in Germany found no statistically significant increase in major birth defects following first trimester mRNA COVID-19 vaccination. While slightly higher rates of some anomalies were observed in vaccinated pregnancies, no consistent patterns or causal links emerged.

11 Jun 2025

Eva1 targeted CAR T cells successfully eliminate tumors in preclinical study

CAR-T cells are specialized immune cells genetically modified to recognize and attack cancer cells. Researchers at Nagoya University in Japan and their collaborators have developed new CAR-T cells to target malignant tumors.

11 Jun 2025

Chromium-rich fiber supplement keeps you fuller and reduces insulin spikes

A single dose of a chromium-enriched glucomannan-fructo-oligosaccharide fiber complex significantly reduced postprandial insulin and increased fullness in healthy adults, without affecting blood glucose. These findings highlight the potential of this functional fiber blend to support appetite control and metabolic health.

10 Jun 2025

Psilocybin rewires the brain for weeks, study finds

Psilocybin induces consistent and sustained changes in brain network connectivity, particularly between the hippocampus and default mode network, as shown using high-resolution fMRI in healthy adults. These neural effects, distinct from those produced by methylphenidate, may underlie the drug’s psychological benefits and were reproducible within individuals over time.

10 Jun 2025

Is it time to rethink dairy? Here’s what 25 years of research reveals for women

A 25-year Finnish cohort study found that higher intake of liquid dairy products lowers the risk of osteoporotic and general fractures in older women. Cheese consumption was specifically linked to reduced hip fracture risk, while overall fracture risk was unaffected by cheese.

10 Jun 2025

Is that evening glass of wine really good for your heart?

A comprehensive AHA review finds overwhelming evidence that heavy alcohol use increases cardiovascular disease risk, while the benefits of low-to-moderate drinking remain unproven and uncertain. The authors recommend prioritizing proven heart-healthy habits over alcohol for cardiovascular protection.

10 Jun 2025