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Protein identified as key to preventing fat build-up and related diseases

Accumulation of fat molecules is detrimental to the cell. Researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), have made a breakthrough in understanding how our cells manage to stay healthy by recycling important fat molecules.

11 Feb 2025

Mechanical heart valves offer better long-term survival for patients aged 50-70

Patients aged between 50 to 70 years with a mechanical heart valve replacement had better long-term survival compared to those with a biological valve, new research led by the University of Bristol has found.

11 Feb 2025

Machine learning tool predicts cancer treatment response based on genetic mutations

A groundbreaking study led by USC Assistant Professor of Computer Science Ruishan Liu has uncovered how specific genetic mutations influence cancer treatment outcomes-insights that could help doctors tailor treatments more effectively.

11 Feb 2025

UCLA study reveals key role of mismatch repair genes in Huntington’s disease

A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease and triggering downstream pathologies and motor impairment, shedding light on disease mechanisms and potential new ways to develop therapies.

11 Feb 2025

New guidelines urge caution with ketamine use for mental health treatment

The anesthetic ketamine is being hailed as a breakthrough therapy for people with post-traumatic stress disorder (PTSD), treatment-resistant depression and other mood disorders.

11 Feb 2025

New light-sensitive chemicals show promise for treating aggressive breast cancers

Scientists have developed new light-sensitive chemicals that can radically improve the treatment of aggressive cancers with minimal side effects.

11 Feb 2025

UVA launches trial to test AI-powered device for diabetes management

For people living with Type 1 Diabetes (T1D), keeping blood sugar levels in check is a constant challenge.

11 Feb 2025

Insilico Medicine announces preclinical drug discovery benchmarks from 2021 to 2024

Insilico Medicine ( "Insilico") , a clinical stage generative artificial intelligence (AI)-driven biotechnology company today announced a set of preclinical drug discovery benchmarks from the 22 developmental candidate nominations achieved by its platform from 2021 to 2024.

11 Feb 2025

Broccoli sprouts may help prediabetes, but only with the right gut bacteria

Broccoli sprout extract (BSE) modestly lowered fasting blood glucose in prediabetes, but its effectiveness depended on gut microbiota, particularly the BT2160 operon.

11 Feb 2025

Alzheimer’s escape: How one man defied his genetic fate for nearly two decades

A groundbreaking study reveals how a rare combination of genetics, proteomics, and environmental factors may hold the key to delaying or preventing Alzheimer's, challenging long-held assumptions about the disease.

11 Feb 2025

One shot to lower cholesterol for life? Scientists unlock a groundbreaking gene therapy

Researchers developed an epigenetic editing approach to silence the PCSK9 gene, achieving long-term cholesterol reduction without altering DNA, offering a potential one-time treatment for high cholesterol.

11 Feb 2025

Innovative brain tumor model offers hope for personalized cancer treatments

Scientists from the German Cancer Research Center (DKFZ) and ShanghaiTech University have developed an innovative method for growing brain tumors of individual patients in the laboratory that mimic the original structure and the molecular property of the parental tumor as closely as possible.

11 Feb 2025

Lung signals trigger blood clot formation in cancer patients

Blood clots form in response to signals from the lungs of cancer patients—not from other organ sites, as previously thought—according to a preclinical study by Weill Cornell Medicine, Memorial Sloan Kettering Cancer Center and University of California San Diego Health. Clots are the second-leading cause of death among cancer patients with advanced disease or aggressive tumors.

11 Feb 2025

Diabetes medications may help lower COPD flare-up risk, study finds

The study reveals SGLT-2is are linked to fewer COPD exacerbations in type 2 diabetes, suggesting a need for further clinical trials to confirm these findings.

11 Feb 2025

Study explores microbiome reboot to prolong effect of Crohn's disease therapy

A special liquid diet, known as exclusive enteral nutrition, is an essential therapy for Crohn's disease. Patients consume only this formula for six to eight weeks, completely avoiding solid foods. However, the exact reasons why this is helpful were previously unclear.

11 Feb 2025