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Researchers explore new approach to target rare epileptic disorders

Humans have tens of thousands of genes, many of which produce proteins essential to basic bodily functions.

18 Jun 2025

Can salt substitutes lower blood pressure in diabetes? A new Cochrane review aims to find out

Researchers will systematically review whether replacing regular sodium salt with alternatives like potassium or magnesium salts helps lower blood pressure in adults with diabetes. The protocol outlines a rigorous plan to evaluate blood pressure effects, safety, and adherence using data from RCTs and quasi-RCTs.

18 Jun 2025

Uppsala researchers create 3D-printed human nerve tissue model

With the aid of a 3D printer, researchers at Uppsala University have succeeded in creating a model that resembles human nerve tissue.

18 Jun 2025

Can a Japanese diet help with depression? Large study says yes

A large cross-sectional study of 12,499 Japanese workers found that higher adherence to traditional or modified Japanese diets was associated with a lower prevalence of depressive symptoms. The findings suggest that culturally rooted dietary patterns may support mental well-being, especially among educated adults.

18 Jun 2025

Equal access, unequal impact: Parkinson’s hits minorities harder in the UK

Researchers in East London found that South Asian and Black Parkinson’s disease patients experience more severe motor and cognitive symptoms than White patients. Despite similar access to diagnosis, disparities persist, highlighting the need for more inclusive and culturally sensitive care.

18 Jun 2025

Inhibiting RNA Polymerase 1 suppresses tumor growth in hard-to-treat cancers

Researchers at the Johns Hopkins Kimmel Cancer Center and Department of Radiation Oncology and Molecular Radiation Sciences uncovered a new tumor-suppressive response that could lead to novel therapies targeting hard-to-treat cancers.

18 Jun 2025

Immune cell signatures explain variations in systemic sclerosis severity

Treating rare diseases can be complicated at the best of times, and it gets even more complicated when different patients with the same disease exhibit different symptoms.

18 Jun 2025

Living near microplastic polluted waters linked to higher risk of heart and metabolic diseases

Living in a U.S. coastal county bordered by ocean waters with very high concentrations of microplastics may increase the risk of heart and metabolic diseases, such as Type 2 diabetes, coronary artery disease and stroke.

18 Jun 2025

New switchable CAR-T therapy enters phase 1 trial for advanced breast cancer

The Calibr-Skaggs Institute for Innovative Medicines, the drug development division of Scripps Research, today announced a milestone in cancer treatment with the dosing of the first patient in a phase 1 trial (NCT06878248) evaluating CLBR001 + ABBV-461, a modular, switchable chimeric antigen receptor T cell (sCAR-T) therapy in patients with advanced or metastatic breast cancer who have no suitable treatment options.

18 Jun 2025

CAR T-cell therapy successfully treats rare autoimmune disease of the peripheral nervous system

Physicians from Bochum have used a cancer treatment method to treat severe autoimmune diseases.

18 Jun 2025

Interferon pathway genes linked to treatment success in juvenile arthritis

A set of genes that could be used to help doctors predict which children will respond well to treatment for juvenile idiopathic arthritis (JIA) have been identified by researchers at UCL and Great Ormond Street Hospital for Children (GOSH), who are part of the CLUSTER Consortium.

18 Jun 2025

Heart scan study reveals low-fiber diets drive dangerous heart plaques

A Swedish study links low-fiber, high-red meat diets to increased coronary artery plaque risk, highlighting the importance of dietary choices for heart health.

18 Jun 2025

Grammatical errors could aid in the early detection of schizophrenia

Meta-analysis shows syntax deficits in schizophrenia, emphasizing the role of language in diagnosis and the development of effective therapeutic strategies.

18 Jun 2025

Compound-level diet analysis sheds light on hidden triggers in IBD

Dutch researchers identified specific food compounds that influence remission and flare risk in patients with inflammatory bowel disease. The study shows compound-level dietary analysis could help personalize IBD management and clarify conflicting advice about diet.

18 Jun 2025

Cannabis use associated with increased risk of stroke and heart attacks

Cannabis use is linked to a doubling in the risk of dying from cardiovascular disease, with significantly heightened risks of having a stroke or acute coronary syndrome-sudden reduced or blocked blood flow to the heart-finds a pooled analysis of real world data, published online in the journal Heart.

18 Jun 2025

Heart disease markers may predict future cancer risk

Cancer and heart disease, two leading causes of death worldwide, may be more connected than we previously thought, according to a new UCLA Health study revealing that certain cardiac blood markers can strongly predict future cancer risk-even in people with no history or symptoms of heart disease.

18 Jun 2025

What matters more for diabetes risk: lifestyle or body weight?

A large, multi-ethnic US cohort study found that combining healthy lifestyle factors—non-smoking, regular physical activity, a healthy diet, and moderate alcohol consumption into a Lifestyle Risk Factor Index (LSRI) was linked to a significantly lower risk of type 2 diabetes. However, BMI was a stronger predictor of diabetes risk, and the impact of lifestyle varied across ethnic groups.

18 Jun 2025

Global warming fuels an alarming increase in obstructive sleep apnea cases

Global warming significantly raises the risk and severity of obstructive sleep apnea (OSA), especially on hotter nights. A multinational sensor-based study links temperature-driven OSA increases to major losses in healthy life years and billions in economic costs.

17 Jun 2025

OCCAM Immune and Cancer Research Institute join forces to advance immunotherapy

In a new collaboration that could transform how cancer is treated, OCCAM Immune-a Mount Sinai initiative focused on understanding the immune system's role in disease-is partnering with the Cancer Research Institute (CRI) to unlock the secrets of how the immune system responds to advanced therapies.

17 Jun 2025

Colorectal cancer patients fare better when diagnosed before other cancers

A new study using one of the world's largest cancer registries shows that patient outcomes can be significantly impacted depending on when colorectal cancer (CRC) is diagnosed related to other cancers.

17 Jun 2025