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Researchers develop innovative mouse model for studying cancer immunotherapy

Immunity plays a central role in the fight against cancer. Many of the current immunotherapies aim at helping the patient's immune system to better recognize cancer cells - by using engineered antibodies - or by simply providing it with new cells, pre-equipped to search and destroy cancer.

12 Oct 2024

Innovative tissue expansion technique transforms conventional microscopy capabilities

A classical way to image nanoscale structures in cells is with high-powered, expensive super-resolution microscopes. As an alternative, MIT researchers have developed a way to expand tissue before imaging it - a technique that allows them to achieve nanoscale resolution with a conventional light microscope.

12 Oct 2024

Harnessing neural networks to forecast treatment outcomes in small cell lung cancer

As immunotherapy makes breakthrough progress in the treatment of small cell lung cancer (SCLC), predicting treatment outcomes has become a focal point in clinical practice. Immunotherapy combined with chemotherapy has been approved as first-line therapy for small cell lung cancer due to its survival benefit in randomized controlled trials.

12 Oct 2024

Innovative approaches to lymphatic pain relief in breast cancer patients

Among the 7.8 million women with breast cancer worldwide, at least 33% to 44% are affected by lymphatic pain. Breast cancer survivors usually suffer lymphatic pain in the ipsilateral body or upper limb, and pharmacological approaches are not effective for lymphatic pain.

12 Oct 2024

Newly identified 'headspin hole' affects breakdancers’ scalp health

Breakdancers may be at risk of developing a condition caused by repeatedly doing a cardinal move of their practice and performance - the headspin - warn doctors in the journal BMJ Case Reports.

12 Oct 2024

Gene editing enhances immunotherapy success by preventing T-cell exhaustion

Immunotherapy, using a patient's own immune system to treat disease, has shown promise in some patients with cancer but has not worked in most.

12 Oct 2024

Researchers uncover new mechanism of stem cell differentiation linked to cancer progression

A study led by Umeå University, Sweden, have made new discoveries about how stem cells develop and transition into specialized cells. The discovery can provide increased understanding of how cells divide and grow uncontrollably so that cancer develops.

12 Oct 2024

New research explores hydrogen sulfide as treatment for obesity

Therapies that deliver hydrogen sulfide to cells could one day become the basis of new treatments for obesity and related diseases, new research has concluded.

10 Oct 2024

Oral health strategies for healthy aging: A call to action

Research explores the connection between aging populations and oral health, proposing an integrated model to address health challenges in older adults, with a focus on policy changes in the UK.

10 Oct 2024

Mount Sinai launches new center for complex chronic illnesses

Mount Sinai's Department of Rehabilitation and Human Performance has announced the grand opening of the Cohen Center for Recovery From Complex Chronic Illnesses (CoRE), providing clinical care for patients with conditions such as long Lyme disease/Lyme+, long COVID, and other infection-associated complex chronic illnesses such as myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and Ehlers-Danlos syndrome (EDS).

10 Oct 2024

Excess sugar consumption triggers inflammation and dysbiosis, worsening periodontal disease

Research explores how excessive sugar consumption can drive systemic inflammation, disrupt the gut and oral microbiomes, and contribute to periodontal inflammation, with implications for global health.

10 Oct 2024

New funding to strengthen stroke care systems in Minnesota and South Dakota

Across the United States, more than 90% of stroke patients have some form of disability as a result and more than 11% experience a second stroke within a year.

10 Oct 2024

Researchers identify cause and potential therapeutic approach for diabetic kidney disease

Diabetic kidney disease – a complication of diabetes – is considered the leading cause of chronic kidney disease and kidney failure worldwide.

10 Oct 2024

MSU researchers test new nanotherapy infusion to target arterial inflammation

Inflammation of the arteries is a primary precursor and driver of cardiovascular disease - the No. 1 killer of people in the United States. This inflammation is associated with the buildup of dangerous plaque inside the arteries.

10 Oct 2024

Researchers awarded $7 million to innovate probiotic treatments for lung infections

University of California San Diego and University of California Berkeley researchers have been awarded up to $7 million from the Advanced Research Projects Agency for Health (ARPA-H) to conduct research under the PROTECT project - Pro/Prebiotic Regulation for Optimized Treatment and Eradication of Clinical Threats.

10 Oct 2024

Research highlights importance of feedback in youth mental health care

A study in the Journal of the American Academy of Child and Adolescent Psychiatry (JAACAP), published by Elsevier, reports that the effectiveness of youth mental health services can be improved by providing clinicians with frequent youth and family feedback and coaching leaders to support clinicians' effective use of the feedback.

10 Oct 2024

NIH funding supports investigation of skeletal stem cells in craniofacial bone disorders

Researchers at UTHealth Houston have been awarded an $8.1 million grant by the National Institutes of Health (NIH) to examine skeletal stem cells as potential drivers of craniofacial bone diseases and deformities.

10 Oct 2024

CKMT2 regulates mitochondrial function and energy metabolism in type 2 diabetes

Creatine kinase M2 (CKMT2) plays a key role in mitochondrial dysfunction in type 2 diabetes, affecting energy metabolism in skeletal muscle.

10 Oct 2024

AI-driven oculomics assesses HbA1c for cardiovascular risk

Study demonstrates the potential of using artificial intelligence in oculomics to assess HbA1c levels from fundus images. By analyzing over 6,000 images, the researchers found that diverse datasets are key to minimizing bias and improving model reliability across different populations.

10 Oct 2024

Researchers decode how the brain identifies and responds to odors

Investigating neuronal activity in the brain, this study highlights how olfactory cues are processed, emphasizing the roles of the piriform cortex and amygdala.

10 Oct 2024