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Experimental drug paired with a standard-care medication offers hope for kidney disease patients

In a clinical trial of patients with chronic kidney disease, an experimental drug significantly reduced albuminuria - albumin in urine, a sign of kidney damage - for 50% of participants.

15 Dec 2023

Physics-based metric predicts aortic aneurysm growth with 98% accuracy

Northwestern University researchers have developed the first physics-based metric to predict whether or not a person might someday suffer an aortic aneurysm, a deadly condition that often causes no symptoms until it ruptures.

15 Dec 2023

Unlocking radiation resistance: Missing protein key to suppressing cancer-fighting cells

A new study finds that radiation therapy (RT) suppresses a key protein called bone morphogenetic protein and activin membrane-bound inhibitor (BAMBI) and activates immune suppressive cells.

15 Dec 2023

Young mental health sufferers stuck in hospital limbo, study finds

Young people needing beds urgently for their mental health needs are waiting for long periods on acute general hospital wards, before being placed on wards far from where they live, according to a new study.

15 Dec 2023

Researchers reveal a connection between cellular metabolism and depression, suicidal ideation

Major depressive disorder affects 16.1 million adults in the United States and costs $210 billion annually. While the primary symptoms of depression are psychological, scientists and doctors have come to understand that depression is a complex disease with physical effects throughout the body.

15 Dec 2023

Light physical activity emerges as powerful tool to reverse childhood inactivity's cholesterol risk

Increased sedentary time in childhood can raise cholesterol levels by two thirds as an adult, leading to heart problems and even premature death - but a new study has found light physical activity may completely reverse the risks and is far more effective than moderate-to-vigorous physical activity.

15 Dec 2023

Addiction stigma discourages many people from seeking treatment

Addiction is one of society's most misunderstood and rebuked health conditions. That stigma discourages many people from seeking treatment for substance dependence, according to a new report published in Psychological Science in the Public Interest, a journal of the Association for Psychological Science.

15 Dec 2023

Science’s Breakthrough of the Year: GLP-1 agonists can blunt obesity-associated health problems

Science has named the development of glucagon like peptide-1 (GLP-1) agonists and this year's discovery that these drugs can blunt obesity-associated health problems as its 2023 Breakthrough of The Year.

15 Dec 2023

RNA-seq analysis reveals key factors in intervertebral disc degeneration

In a rapid communication published in the journal Genes & Diseases, researchers from Chongqing Medical University and Yongchuan Traditional Chinese Medicine Hospital of Chongqing have unveiled crucial insights into the factors that might influence Intervertebral Disc Degeneration (IDD).

15 Dec 2023

Wnt signaling holds promise for tailored immunotherapy in microsatellite-instable colorectal cancer

Colorectal cancer presents with varying clinical characteristics due to tumor heterogeneity. Microsatellite instability (MSI), present in 10%-15% of CRC cases, indicates a different clinical trajectory than microsatellite stable (MSS) patients.

15 Dec 2023

Alzheimer's may worsen COVID-19 outcomes via olfactory mucosa changes

A new study identifies alterations in the transcriptomic signatures in human olfactory mucosal cells of individuals with Alzheimer's disease following SARS-CoV-2 infection, potentially contributing to exacerbated COVID-19 outcomes.

15 Dec 2023

New LMU-led DFG Research Unit eyes innovative gene therapies for retinal diseases

A new LMU-led DFG Research Unit is developing innovative approaches for treating retinal diseases.

15 Dec 2023

Blueprint Medicines announces approval of AYVAKYT for treatment of ISM patients in Europe

Blueprint Medicines Corporation today announced the European Commission has approved AYVAKYT® (avapritinib) for the treatment of adult patients with indolent systemic mastocytosis (ISM) with moderate to severe symptoms inadequately controlled on symptomatic treatment. AYVAKYT is the first and only approved therapy for people living with ISM in Europe.

15 Dec 2023

Medical Condition News

Experimental drug paired with a standard-care medication offers hope for kidney disease patients

Physics-based metric predicts aortic aneurysm growth with 98% accuracy

Unlocking radiation resistance: Missing protein key to suppressing cancer-fighting cells

Young mental health sufferers stuck in hospital limbo, study finds

Researchers reveal a connection between cellular metabolism and depression, suicidal ideation

Light physical activity emerges as powerful tool to reverse childhood inactivity's cholesterol risk

Addiction stigma discourages many people from seeking treatment

Science’s Breakthrough of the Year: GLP-1 agonists can blunt obesity-associated health problems

RNA-seq analysis reveals key factors in intervertebral disc degeneration

Wnt signaling holds promise for tailored immunotherapy in microsatellite-instable colorectal cancer

Alzheimer's may worsen COVID-19 outcomes via olfactory mucosa changes

New LMU-led DFG Research Unit eyes innovative gene therapies for retinal diseases

Blueprint Medicines announces approval of AYVAKYT for treatment of ISM patients in Europe

UCL researchers develop new gene therapy to cure severe childhood epilepsy

Fetal hormone GDF15 linked to nausea and vomiting in pregnancy

UH researchers secure NIH grant to tackle buprenorphine's dental side effects

Researchers report progress in the search for more accurate blood markers for acute kidney injury

Can community pharmacists reduce the incidence of skin cancer?

Overweight, not just obesity, drives higher healthcare costs, Norwegian study finds

Uncovering barriers to heart failure medication access for low-income patients

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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