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Middle age: A critical turning point for brain health and cognition

Review emphasizes the significance of midlife for cognitive trajectories and brain health, advocating for research models that capture non-linear changes to better understand the unique processes occurring during this period.

20 Mar 2024

Investigational gene therapy shows promise for rare childhood neurodegenerative disease

An investigational gene therapy for a rare neurodegenerative disease that begins in early childhood, known as giant axonal neuropathy (GAN), was well tolerated and showed signs of therapeutic benefit in a clinical trial led by the National Institutes of Health.

20 Mar 2024

Building a sense of community key to improving people's mental health

University of Queensland research has found building a sense of community is key to improving people's mental health, particularly in low socio-economic suburbs.

20 Mar 2024

Frequent musculoskeletal pain linked with increased risk of early retirement

Frequent musculoskeletal pain is linked with an increased risk of exiting work and retiring earlier, according to a new study from the University of Portsmouth.

20 Mar 2024

Enhancing the safety and efficacy of breast and ovarian cancer treatment

Some anti-cancer treatments not only target tumour cells but also healthy cells. If their effects on the latter are too strong, their use can become limiting.

20 Mar 2024

Treatment for anxiety and depression associated with improved heart disease outcomes

Treating anxiety and depression reduced emergency room visits and rehospitalizations among people with heart disease, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

20 Mar 2024

Risk factors for serious inflammatory conditions in IBD patients identified

Investigators at Cedars-Sinai have identified risk factors that make inflammatory bowel disease (IBD) patients susceptible to developing serious conditions in other parts of their bodies.

20 Mar 2024

Hearing loss linked to accelerated Alzheimer's progression via GDF1 pathway

Study unveils the GDF1 signaling pathway's role in mitigating the adverse effects of hearing loss on Alzheimer's disease, spotlighting potential avenues for therapeutic development.

20 Mar 2024

Joint hypermobility linked to longer COVID-19 recovery time

Study shows that individuals with generalized joint hypermobility have a 30% higher risk of not recovering from acute COVID-19, highlighting the need for tailored treatment and care.

20 Mar 2024

New schools in England face pollution peril

Study uncovers high pollution levels at new school sites in England, surpassing WHO guidelines, raising concerns about children's health and the need for policy reforms to ensure safer environments.

20 Mar 2024

Lactate's role in driving cancer cachexia uncovered

Study highlights the significant role of lactate in promoting cancer cachexia via activation of the adipose-specific G-protein-coupled receptor 81 (GPR81), suggesting new therapeutic targets for this condition.

20 Mar 2024

Study finds higher burden of neurologic disease after influenza than COVID-19 hospitalization

People who have an influenza infection are more likely to need medical care for neurologic disorders within the next year than people who have a COVID-19 infection, according to a study published in the March 20, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

20 Mar 2024

Study reveals cellular dynamics of multiple sclerosis lesions

Using advanced methodology, scientists in Sweden were able to reveal at the cellular level how lesions in multiple sclerosis develop.

20 Mar 2024

Free weekly fresh produce linked to improved nutrition and reduced cardiovascular risk

Programs that provided free, weekly home delivery of fresh fruits and vegetable from local farms helped improve recipients' nutrition levels, physical activity levels and cardiovascular disease risk factors, according to preliminary research to be presented at the American Heart Association's Epidemiology and Prevention│Lifestyle and Cardiometabolic Scientific Sessions 2024, held March 18- 21, in Chicago.

20 Mar 2024

Aging affects regulatory T cells' ability to promote myelin regeneration

Regulatory T lymphocytes are cells that are responsible for regulating the immune system and have regenerative functions in many contexts, including myelin restoration.

20 Mar 2024

Skin biopsy test shows promise in diagnosing Parkinson's disease and synucleinopathies

In a paper published in the Journal of the American Medical Association (JAMA), neurologists at Beth Israel Deaconess Medical Center (BIDMC) showed that a simple skin biopsy test detects an abnormal form of alpha-synuclein, the pathological hallmark of Parkinson's disease and the subgroup of neurodegenerative disorders known as synucleinopathies, at high positivity rates.

20 Mar 2024