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Liquid biopsy may offer new tools for personalized immunotherapy in lung cancer

Using a "liquid biopsy" to study genetic material from tumors shed into the bloodstream together with immune cells could help clinicians predict which patients with advanced lung cancers are responding to immunotherapies and which patients may develop immune-related side effects several months later, according to research directed by investigators at the Johns Hopkins Kimmel Cancer Center, the Bloomberg~Kimmel Institute for Cancer Immunotherapy and Allegheny Health Network Cancer Institute in Pittsburgh.

12 Dec 2023

Self-monitoring shows promise in managing high blood pressure and pre-eclampsia in pregnancy

Study suggests that self-monitoring of blood pressure may aid in the early detection and management of high blood pressure and pre-eclampsia in high-risk pregnancies, offering a potential shift in prenatal care strategies.

12 Dec 2023

Vegetarian diet linked to lower risk of insomnia, study suggests

Study reveals that following a vegetarian diet may reduce the risk of insomnia, particularly in men, potentially due to higher intakes of healthful plant-based foods and lower consumption of animal products.

12 Dec 2023

Hidden danger: Uncontrolled hypertension linked to increased kidney failure and mortality

High blood pressure is called the silent killer because symptoms can remain hidden until a medical crisis strikes.

12 Dec 2023

Adherence to second-line drugs for Type 2 diabetes can be hit or miss, study reports

Most patients with Type 2 diabetes will end up needing to add a second-line medication after metformin - the go-to primary drug for glucose management - to control their blood sugar levels.

12 Dec 2023

Study unlocks protein clues to aggressive lymphoma transformation

Researchers have come one step closer to answering why, in some patients, a type of lymphoma changes from indolent to aggressive, and in particular they are closer to identifying which patients are at high risk of this change happening.

12 Dec 2023

UVA atlas unveils cellular blueprint of atherosclerosis

University of Virginia School of Medicine researchers have created an "atlas of atherosclerosis" that reveals, at the level of individual cells, critical processes responsible for forming the harmful plaque buildup that causes heart attacks, strokes and coronary artery disease.

12 Dec 2023

AI-based risk model for breast cancer screening

Researchers assess the performance of an artificial intelligence-based risk model for breast cancer screening in Europe.

12 Dec 2023

Effectiveness of environmental interventions in managing autism

Researchers evaluate the health-related outcomes of nature-based interventions in children with autism.

12 Dec 2023

Navigating post-pandemic school reintegration: A comprehensive assessment of mental health in children with special educational needs

Researchers examine changes in mental health among children and adolescents with special educational needs after COVID-19-related school closures.

12 Dec 2023

Jena scientist receives grant for research on mitochondrial and neurodegenerative disease treatments

Dr. Kanstantsin Siniuk, postdoctoral researcher in the project group of Dr. Helmut Pospiech at the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) Jena, has secured a 96,000 euro grant from the BMBF's GO-Bio initial program for his pioneering project on mitochondrial and neurodegenerative disease treatments.

12 Dec 2023

Gene therapy shows promise for arrhythmogenic cardiomyopathy

Researchers evaluated the effectiveness of adeno-associated virus (AAV)-mediated Plakophilin 2 (PKP2) delivery in treating arrhythmogenic cardiomyopathy (ACM).

12 Dec 2023

How does the combined effect of smoking and HIV infection influence the aging-related manifestations?

The combination of human immunodeficiency virus (HIV) infection and smoking influence.

12 Dec 2023

Revolutionizing diabetes care: tPBM therapy proves effective in restoring microglial health

Transcranial photobiomodulation (tPBM) treatment affected insulin therapy on microglial function.

12 Dec 2023

New combination treatment offers hope for older patients with mantle cell lymphoma

The phase 2 trial PrE0405 met its primary endpoint, achieving a complete response (CR) rate of 85% in 33 patients over the age of 60 with mantle cell lymphoma (MCL) who received bendamustine and rituximab, a standard chemo-immunotherapy treatment, along with venetoclax, which is investigational in this setting.

11 Dec 2023

New antibody combination shows 'surprising' results in high-risk follicular lymphoma trial

Researchers conducting a Phase 2 clinical trial at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine say a new combination of antibody therapies produced a 'surprisingly high' response rate in patients with high-risk follicular lymphoma, a type of non-Hodgkin lymphoma.

11 Dec 2023

Tirzepatide maintains weight loss and improves cardiometabolic health in SURMOUNT-4 trial

The current class of anti-obesity drugs is proving remarkably effective at removing excess pounds. However, a phase 3 randomized clinical trial led by researchers at Weill Cornell Medicine and NewYork-Presbyterian found that people who stopped taking the medication regained much of that weight within a year.

11 Dec 2023

Synbiotic formula shows promise in reducing long COVID symptoms

Study finds that the synbiotic preparation SIM01 significantly reduces post-acute COVID-19 syndrome symptoms in patients, including fatigue, memory issues, and gastrointestinal distress, indicating its potential as a treatment for long COVID.

11 Dec 2023

Study: Risk of dying from cancer depends on where you live in England

The risk of dying from the 10 forms of cancer with the largest death toll for men and women varies massively depending on the district in England where people live, according to a study published in The Lancet Oncology.

11 Dec 2023

Double punch for B-cell lymphomas: CAR T-cell innovation boosts efficacy, cuts toxicity

The Malaghan Institute of Medical Research in collaboration with Wellington Zhaotai Therapies Limited today announced results of its phase 1 dose escalation trial of a new third-generation anti-CD19 chimeric antigen receptor (CAR) T-cell therapy to be presented at the American Society of Hematology (ASH) Annual Meeting in San Diego on 11 December, 3pm.

11 Dec 2023

Medical Condition News

Liquid biopsy may offer new tools for personalized immunotherapy in lung cancer

Self-monitoring shows promise in managing high blood pressure and pre-eclampsia in pregnancy

Vegetarian diet linked to lower risk of insomnia, study suggests

Hidden danger: Uncontrolled hypertension linked to increased kidney failure and mortality

Adherence to second-line drugs for Type 2 diabetes can be hit or miss, study reports

Study unlocks protein clues to aggressive lymphoma transformation

UVA atlas unveils cellular blueprint of atherosclerosis

AI-based risk model for breast cancer screening

Effectiveness of environmental interventions in managing autism

Navigating post-pandemic school reintegration: A comprehensive assessment of mental health in children with special educational needs

Jena scientist receives grant for research on mitochondrial and neurodegenerative disease treatments

Gene therapy shows promise for arrhythmogenic cardiomyopathy

How does the combined effect of smoking and HIV infection influence the aging-related manifestations?

Revolutionizing diabetes care: tPBM therapy proves effective in restoring microglial health

New combination treatment offers hope for older patients with mantle cell lymphoma

New antibody combination shows 'surprising' results in high-risk follicular lymphoma trial

Tirzepatide maintains weight loss and improves cardiometabolic health in SURMOUNT-4 trial

Synbiotic formula shows promise in reducing long COVID symptoms

Study: Risk of dying from cancer depends on where you live in England

Double punch for B-cell lymphomas: CAR T-cell innovation boosts efficacy, cuts toxicity

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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