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Combination of dasatinib and blinatumomab offers effective treatment for older Ph+ ALL patients

Older patients with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) who were not good candidates for the standard treatment of intensive chemotherapy had a median overall survival (OS) of 6.5 years on an alternate regimen of dasatinib and blinatumomab.

11 Dec 2023

Phase I clinical trial of new CAR T cell therapy AT101 shows promising early responses

Early results from a Phase I clinical trial of AT101, a new CAR T cell therapy that uses a distinct binding mechanism to target CD19, show a 100 percent complete response (CR) rate at the higher dose levels studied in the trial, according to researchers from the University of Pennsylvania Perelman School of Medicine and Penn Medicine's Abramson Cancer Center.

11 Dec 2023

New organoid model could revolutionize neuroendocrine tumor research

The Organoid Group (Hubrecht Institute) and the Rare Cancers Genomics Team (IARC/WHO) found a way to grow samples of different types of neuroendocrine tumors (NETs) in the lab.

11 Dec 2023

Study provides a better understanding of how the brain responds to injuries

A new study published in Proceedings of the National Academy of Sciences Nexus provides a better understanding of how the brain responds to injuries.

11 Dec 2023

Advanced MRI offers insights into the underlying mechanisms of neurological problems after COVID-19

Researchers at Linköping University have examined the brains of 16 patients previously hospitalized for COVID-19 with persisting symptoms.

11 Dec 2023

Empowering communities: Know Diabetes by Heart initiative awards grants to combat cardiovascular disease

The American Diabetes Association and the American Heart Association have awarded grants to 10 community organizations to help people living with Type 2 diabetes lower their risk for cardiovascular diseases like heart attack, heart failure and stroke.

11 Dec 2023

New report provides latest update on cardiovascular disease burden and trends

A world without cardiovascular disease (CVD) is possible, yet millions of lives are lost prematurely to heart disease each year, according to the new Global Burden of Disease (GBD) special report published today in the Journal of the American College of Cardiology.

11 Dec 2023

Is there an association between meat and fish consumption and non-alcoholic fatty liver disease?

The associations between meat and fish consumption and the risk of non-alcoholic fatty liver disease (NAFLD).

11 Dec 2023

Groundbreaking online community connects Progeria patients worldwide

A ground-breaking online community has been launched to allow people with the rare disease Progeria to communicate regardless of their location or language.

11 Dec 2023

Researchers develop novel exosome-based drug delivery system to treat Alzheimer's disease

A research team led by Hong Kong Baptist University (HKBU) has developed a novel drug delivery system for Alzheimer’s disease (AD).

11 Dec 2023

New map offers valuable insights into the underlying mechanisms of neurodevelopmental disorders and cancer

Scientists have created the first extensive map showing how all possible genetic changes can affect health in the gene DDX3X, leading to valuable insights into the underlying mechanisms of neurodevelopmental disorders and cancer.

11 Dec 2023

Phase 2 trial data shows safety, tolerability and efficacy of imlifidase in GBS patients

Hansa Biopharma today announced positive high-level data from the 15-HMedIdeS-09 phase 2 trial that demonstrated imlifidase was safe and well tolerated when administered prior to standard of care, including rapid improvement in disease-related efficacy measures.

11 Dec 2023

Study shows low-fat milk may increase prediabetes risk, high-fat yogurt lowers it

Study in The American Journal of Clinical Nutrition found an association between dairy intake and prediabetes risk, highlighting that low-fat milk consumption may increase prediabetes risk, while high-fat yogurt is linked to a reduced risk, particularly among highly educated individuals.

10 Dec 2023

Natural supplements Guayusa tea and Lion’s Mane boost cognitive performance, study finds

Study shows that Guayusa extract and Nordic Lion’s Mane (LM) improve subjective cognitive perception and objective cognitive performance, highlighting their potential benefits in enhancing cognitive functions and mood.

10 Dec 2023

Varied early symptoms of bacterial meningitis in adults and children highlight diagnostic challenges

This study in Scientific Reports reveals that symptoms of community-acquired bacterial meningitis (CABM) vary between children and adults, emphasizing the need for tailored approaches in early diagnosis and treatment to improve outcomes.

10 Dec 2023

Global study reveals hypertension common among middle-aged couples

Study reports high prevalence of concordant hypertension among middle-aged heterosexual couples in England, the US, India, and China, suggesting couple-centered interventions could be effective in hypertension management.

10 Dec 2023

Breakthrough in pancreatic cancer treatment: Inhibiting specific enzymes slows tumor progression

Study demonstrates that inhibiting stromal class I histone deacetylases (HDACs) can effectively slow down pancreatic cancer progression, shedding light on a new therapeutic approach targeting the tumor microenvironment.

10 Dec 2023

Study assesses links between early negative life events, orbitofrontal cortical thickness and depression in young adults

Study found that early negative life events predict depressive symptoms in young adulthood, but not through accelerated thinning of the orbitofrontal cortex (OFC) across adolescence, challenging previous assumptions about the brain's structural changes and mental health.

10 Dec 2023

Study links air pollution to increased risks of preterm birth and low birth weight

Study highlights the importance of reducing air pollution exposure during pregnancy to prevent risks like preterm birth and low birth weight, showing a strong correlation between air quality and maternal and neonatal health outcomes.

10 Dec 2023

Study explores the intricate gut-brain-liver connection and its impact on health

Study reviews the gut-brain-liver axis, revealing the complex interplay between these organs in health and disease and the implications for therapeutic interventions, focusing on how gut microbiota affects liver and brain health.

10 Dec 2023

Medical Condition News

Combination of dasatinib and blinatumomab offers effective treatment for older Ph+ ALL patients

Phase I clinical trial of new CAR T cell therapy AT101 shows promising early responses

New organoid model could revolutionize neuroendocrine tumor research

Study provides a better understanding of how the brain responds to injuries

Advanced MRI offers insights into the underlying mechanisms of neurological problems after COVID-19

Empowering communities: Know Diabetes by Heart initiative awards grants to combat cardiovascular disease

New report provides latest update on cardiovascular disease burden and trends

Is there an association between meat and fish consumption and non-alcoholic fatty liver disease?

Groundbreaking online community connects Progeria patients worldwide

Researchers develop novel exosome-based drug delivery system to treat Alzheimer's disease

New map offers valuable insights into the underlying mechanisms of neurodevelopmental disorders and cancer

Phase 2 trial data shows safety, tolerability and efficacy of imlifidase in GBS patients

Study shows low-fat milk may increase prediabetes risk, high-fat yogurt lowers it

Natural supplements Guayusa tea and Lion’s Mane boost cognitive performance, study finds

Varied early symptoms of bacterial meningitis in adults and children highlight diagnostic challenges

Global study reveals hypertension common among middle-aged couples

Breakthrough in pancreatic cancer treatment: Inhibiting specific enzymes slows tumor progression

Study assesses links between early negative life events, orbitofrontal cortical thickness and depression in young adults

Study links air pollution to increased risks of preterm birth and low birth weight

Study explores the intricate gut-brain-liver connection and its impact on health

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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