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Increased risk of autoimmune disease after Cushing's disease remission

A study of more than 250 persons undergoing surgical therapy for Cushing's disease (CD) or nonfunctioning pituitary adenomas (NFPAs) found that patients who achieved remission of CD were more likely than those with surgically treated NFPAs to develop new-onset autoimmune disease within 3 years after remission.

19 Feb 2024

Sleep-circadian disturbances can trigger or worsen a range of psychiatric disorders

Problems with our sleep and internal body clock can trigger or worsen a range of psychiatric disorders, according to a new review of recent research evidence.

19 Feb 2024

How dopamine influences movement in Parkinson's

Dopamine, a chemical messenger in the brain, is mostly known for its role in how we experience pleasure and reward.

19 Feb 2024

Is snoring related to high blood pressure?

Home-based monitoring reveals a strong link between snoring duration and uncontrolled hypertension, highlighting the need for snoring to be considered in hypertension management.

19 Feb 2024

Understanding postural tachycardia syndrome in cardiovascular care

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Postural tachycardia syndrome (POTS) is a chronic autonomic disorder characterized by excessive heart rate elevation upon standing or head-up tilt, in the absence of orthostatic hypotension.

19 Feb 2024

Canagliflozin reduces atherosclerosis and modulates inflammatory, oxidative pathways in mice

Announcing a new article publication for Cardiovascular Innovations and Applications journal. This study was aimed at investigating the effect of canagliflozin (Cana) on atherosclerosis and further exploring its potential mechanism. ApoE−/− mice were fed a Western diet (WD) and randomly divided into a WD group and WD+Cana group.

19 Feb 2024

Clinical insights into hypertension following unilateral adrenalectomy

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Patients who undergo adrenalectomy for unilateral primary aldosteronism (PA) may still develop post-surgery hypertension; however, the clinical characteristics and etiology of patients developing recurrent hypertension after adrenalectomy are unclear.

19 Feb 2024

Assessing post-PCI optical flow ratio for improved cardiac risk management

Announcing a new article publication for Cardiovascular Innovations and Applications journal. The goal of this study was to examine the prognostic performance of optical flow ratio (OFR) among patients with coronary artery disease (CAD) after percutaneous coronary intervention (PCI).

19 Feb 2024

New RNA therapy zilebesiran shows promise in lowering blood pressure

Zilebesiran, an RNA interference therapeutic, significantly reduces blood pressure in hypertension patients with a favorable safety profile, offering a potential biannual treatment option.

19 Feb 2024

Selection, optimization, and validation of genetic tests for 10 common diseases

By analyzing millions of small genetic differences across a person's genome, researchers can calculate a polygenic risk score to estimate someone's lifetime odds of developing a certain disease.

19 Feb 2024

Mapping the genomic landscape of Type 2 diabetes

In the largest genome-wide association study to date on Type 2 diabetes, a team of international researchers, co-led by a University of Massachusetts Amherst genetic epidemiologist, has located 1,289 genetic markers associated with Type 2 diabetes (145 of which are newly identified) and generated risk scores for diabetes complications.

19 Feb 2024

Study discovers link between a breakdown product from excess niacin and heart disease

Cleveland Clinic researchers have identified a new pathway that contributes to cardiovascular disease associated with high levels of niacin, a common B vitamin previously recommended to lower cholesterol.

19 Feb 2024

Dietary protein overload linked to increased atherosclerosis risk

University of Pittsburgh School of Medicine researchers discovered a molecular mechanism by which excessive dietary protein could increase atherosclerosis risk.

19 Feb 2024

COVID-19 linked to higher fatigue rates, says study

A study by the CDC and Washington University found COVID-19 significantly increases the risk of developing fatigue and chronic fatigue, with higher incidence rates compared to non-COVID-19 controls.

19 Feb 2024

Can grandparental support improve the mental health of single mothers?

The role of grandparental support in protecting mothers from depression.

19 Feb 2024

Melatonin treatment does not affect insulin resistance of night shift workers

Melatonin treatment does not affect the insulin resistance or the glucose tolerance of night shift workers, according to a new study from the University of Surrey and the University Medical Centre Hamburg.

19 Feb 2024

Single-dose genetic medicine halts the progression of ALS and frontotemporal dementia in mice

Neuroscientists at Macquarie University in Australia have developed a single-dose genetic medicine that has been proven to halt the progression of both ALS and frontotemporal dementia (FTD) in mice – and may even offer the potential to reverse some of the effects of the fatal diseases.

19 Feb 2024