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Universal CAR T cell therapy shows promise for aggressive T cell cancers

A new type of immunotherapy that targets aggressive blood cancers shows promising results alongside manageable side effects, according to the results of an international phase 1/2 clinical trial led by researchers at Washington University School of Medicine in St. Louis.

31 May 2025

Study could change the definition of wound closure in diabetes care

In patients with diabetic foot ulcers that looked healed and met the current definition of a closed wound, closed ulcers with functionally defective skin that lost more body water were likely to re-open, according to a new National Institutes of Health (NIH) Diabetic Foot Consortium study, led by researchers at the University of Pittsburgh and published today in Diabetes Care.

31 May 2025

Men with common genetic variant twice as likely to develop dementia

New research has found that men who carry a common genetic variant are twice as likely to develop dementia in their lifetime compared to women.

31 May 2025

Structural racism and social defeat may drive psychosis in marginalized youth

Prevailing theories about why young people experience psychotic breaks at a young age rely on individual factors like exposure to child abuse, school bullying, or drugs.

30 May 2025

Upper gastrointestinal involvement is common in Egyptian patients with ulcerative colitis

This study investigates upper gastrointestinal tract (UGIT) involvement in patients with ulcerative colitis (UC), a condition traditionally considered limited to the colon.

30 May 2025

Triplet therapy significantly improves survival in BRAF V600E-mutated metastatic colorectal cancer

First-line treatment with the triplet combination of encorafenib, cetuximab and mFOLFOX6 significantly improved survival compared to the standard of care in patients with BRAF V600E-mutated metastatic colorectal cancer, according to new data from the Phase III BREAKWATER trial led by researchers from The University of Texas MD Anderson Cancer Center.

30 May 2025

Cross-cultural analysis reveals differences in socio-cognitive abilities of autistic and non-autistic adults

Emerging theories suggest that communication challenges arise from differing perspectives between autistic and non-autistic partners rather than individual socio-cognitive deficits.

30 May 2025

Researchers report surge in at-home heart attacks and cardiac deaths since COVID pandemic

Heart attacks are the leading cause of death globally, yet some statistics from many different countries suggest these events declined in frequency since the COVID-19 pandemic.

30 May 2025

Research uncovers new links between blood lipid profiles and risk of developing Alzheimer's

People who are at higher risk for heart disease also seem more likely to develop dementia.

30 May 2025

Mass General Brigham researchers share cancer research discoveries at ASCO 2025

Researchers from Mass General Brigham will present research discoveries and outcomes from clinical trials in cancer at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting, held May 30-June 3, in Chicago.

30 May 2025

Pitt professor wins NSF CAREER Award for AI-driven immunotherapy research

The University of Pittsburgh's Natasa Miskov-Zivanov, assistant professor of electrical and computer engineering, has received a prestigious Faculty Early Career Development (CAREER) Award of $581,503 from the National Science Foundation (NSF) for her project titled "Artificial Intelligence-Driven Framework for Efficient and Explainable Immunotherapy Design."

30 May 2025

Study identifies diagnostic aid to accurately predict the recurrence of diabetic foot ulcers

NIH-funded project shows that trans-epidermal water loss could indicate if wounds are fully healed.

30 May 2025

TRR 417 initiative aims to unlock new treatments for colorectal cancer

In the realm of colorectal cancer treatments beyond surgery and radiation, one key question gained prominence in recent years: Is the tumor's DNA repair system defective, making it "microsatellite unstable"? Around 15 to 20 percent of all tumors have this trait, making them likely candidates for successful immunotherapy.

30 May 2025

Genetic factors influence obesity risk in children exposed to gestational diabetes

Children exposed to gestational diabetes in utero with a specific variation of a common gene are at a higher risk of becoming overweight or obese during childhood, according to a new study by researchers at the University of Colorado Anschutz Medical Campus.

30 May 2025

Out-of-hospital cardiac arrest survival drops during COVID-19 with racial disparities

Survival rates for out-of-hospital cardiac arrest (OHCA) fell during the early years of the COVID-19 pandemic, with Black and Hispanic patients experiencing larger decreases in survival, according to a study led by UT Southwestern Medical Center researchers published in Resuscitation.

30 May 2025

TTF1 identified as key biomarker for advanced KRAS G12C-mutated non-small cell lung cancer

Researchers from The University of Texas MD Anderson Cancer Center have identified a new biomarker, TTF-1, that was predictive of survival outcomes for patients with advanced KRAS G12C-mutated non-small cell lung cancer (NSCLC), following treatment with the KRAS targeted therapy sotorasib.

30 May 2025

What drives insulin resistance? Proteomics reveals key pathways in human skeletal muscle

Identifying proteomic signatures of insulin resistance in fasting muscle offers insights for personalized type 2 diabetes therapies based on molecular profiles.

30 May 2025

New insights into decades-old bladder cancer treatment offers clues for immunotherapy

More than three decades ago, the U.S. Food and Drug Administration (FDA) approved Bacillus Calmette-Guérin (BCG) as the first immunotherapy against cancer. And it is still used today to treat early-stage bladder cancer.

29 May 2025

New VR system transforms hand rehabilitation with load free design

In a significant advancement for hand rehabilitation, researchers from Zhengzhou University have introduced a non-hand-worn, load-free VR hand rehabilitation system that could boost therapy development for patients recovering from conditions like stroke and osteoarthritis.

29 May 2025

Early allergen introduction reduces childhood food allergy risk

Investigating allergy prevention, this research highlights early intervention strategies and the promise of biologic treatments in managing allergic conditions.

29 May 2025

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Medical Condition News

Universal CAR T cell therapy shows promise for aggressive T cell cancers

Study could change the definition of wound closure in diabetes care

Men with common genetic variant twice as likely to develop dementia

Structural racism and social defeat may drive psychosis in marginalized youth

Upper gastrointestinal involvement is common in Egyptian patients with ulcerative colitis

Triplet therapy significantly improves survival in BRAF V600E-mutated metastatic colorectal cancer

Cross-cultural analysis reveals differences in socio-cognitive abilities of autistic and non-autistic adults

Researchers report surge in at-home heart attacks and cardiac deaths since COVID pandemic

Research uncovers new links between blood lipid profiles and risk of developing Alzheimer's

Mass General Brigham researchers share cancer research discoveries at ASCO 2025

Pitt professor wins NSF CAREER Award for AI-driven immunotherapy research

Study identifies diagnostic aid to accurately predict the recurrence of diabetic foot ulcers

TRR 417 initiative aims to unlock new treatments for colorectal cancer

Genetic factors influence obesity risk in children exposed to gestational diabetes

Out-of-hospital cardiac arrest survival drops during COVID-19 with racial disparities

TTF1 identified as key biomarker for advanced KRAS G12C-mutated non-small cell lung cancer

What drives insulin resistance? Proteomics reveals key pathways in human skeletal muscle

New insights into decades-old bladder cancer treatment offers clues for immunotherapy

New VR system transforms hand rehabilitation with load free design

Early allergen introduction reduces childhood food allergy risk

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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