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Sacubitril/valsartan shows benefit over enalapril in heart failure caused by Chagas disease

In patients with heart failure (HF) caused by Chagas disease, sacubitril/valsartan was superior to enalapril for the composite primary endpoint, predominantly driven by a significant reduction in N-terminal pro-B-type natriuretic peptide (NT-proBNP), according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

3 Sep 2025

Evolocumab fails to reduce vein graft disease after coronary artery bypass surgery

After coronary artery bypass grafting (CABG), evolocumab did not reduce saphenous vein graft disease rates at 2 years compared with placebo, according to late-breaking research presented in a Hot Line session today at ESC Congress 2025 and simultaneously published in Lancet.

3 Sep 2025

No clear benefit from surgical left atrial appendage occlusion in non-AF patients after valve surgery

No benefit in terms of prevention of ischemic stroke, transient ischemic attack and cardiovascular mortality after 1 year was observed when surgical left atrial appendage occlusion was performed in high-risk non-atrial fibrillation patients after valvular surgery, according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

3 Sep 2025

Study finds sex differences in schizophrenia and bipolar disorder

Schizophrenia and bipolar disorder are serious mental illnesses that affect both males and females, but research in Acta Psychiatrica Scandinavica indicates that sex may influence the characteristics and course of these conditions.

3 Sep 2025

Genetic variant disrupts brain’s cleanup crew increasing Alzheimer’s risk

A Nature study published today and led by researchers at the University of South Florida's USF Health Byrd Alzheimer's Institute pinpoints how a genetic variant disrupts microglia - the brain's "cleanup crew" - increasing the risk of Alzheimer's disease.

3 Sep 2025

Long-term benzodiazepine use linked to poor sleep quality in older adults

Long-term use of benzodiazepine and related drugs has been linked to poorer quality sleep in older adults with insomnia.

3 Sep 2025

Novel vascularized cancer-on-a-chip model reflects the microenvironment of liver tumors

Dr. Vadim Jucaud's lab at the Terasaki Institute has developed a human vascularized liver cancer-on-a-chip model to evaluate vessel remodeling and cell death in response to embolic agents.

3 Sep 2025

Flooding from Hurricane Sandy raises heart disease risk years later

Although the material damage from 2012's Hurricane Sandy may have been repaired, the storm left a lasting impact on cardiovascular health, according to new findings from Weill Cornell Medicine and New York University researchers.

3 Sep 2025

Researchers uncover a promising new therapeutic target for Barth syndrome

Researchers at The Hospital for Sick Children (SickKids) have uncovered a promising new therapeutic target for Barth syndrome, a rare genetic condition with no current cure.

3 Sep 2025

Chronic stress and fatty diet disrupt brain-liver circuit leading to diabetes

This study discovered a circuit in the brain that connects stress with increased glucose and therefore may link stress to type 2 diabetes. In stressful situations, this circuit from the amygdala to the liver naturally provides a burst of energy.

3 Sep 2025

Intravenous cangrelor provides rapid platelet inhibition in cardiogenic shock

Compared with crushed ticagrelor, intravenous cangrelor provided immediate, effective platelet inhibition, with no increase in major bleeding and lower mortality rates in patients with acute myocardial infarction and cardiogenic shock, according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

3 Sep 2025

Home-based hypertension care improves blood pressure control in rural South Africa

Home-based hypertension care led to reductions in systolic blood pressure and improvements in hypertension control in South Africa, according to late-breaking research presented in a Hot Line session today at ESC Congress 2025 and simultaneously published in the New England Journal of Medicine.

3 Sep 2025

Early aspirin discontinuation safe after complete revascularization in acute MI

Among low-risk patients with acute MI who underwent early complete revascularization and received one month of dual antiplatelet therapy (DAPT), P2Y12 inhibitor monotherapy was noninferior to continued DAPT for adverse cardiovascular and cerebrovascular events, while reducing bleeding risk.

3 Sep 2025

Playing joyful music helps ease motion sickness symptoms

Scientists studying ways of improving motion sickness have found that playing different types of music may help people recover more effectively.

3 Sep 2025

Novel ablation approach improves outcomes in patients with persistent atrial fibrillation

Adding digital twin-guided ablation to a standard ablation technique improved outcomes in patients with persistent atrial fibrillation (AF), according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

3 Sep 2025

Ablation methods equally effective for drug-resistant paroxysmal atrial fibrillation

Pulsed field ablation did not have superior efficacy to radiofrequency ablation in patients with drug-resistant paroxysmal (intermittent) atrial fibrillation, according to results from a late-breaking trial presented in a Hot Line session today at ESC Congress 2025.

3 Sep 2025

Roasted Arabica coffee hides powerful antidiabetic molecules

Three novel coffee diterpene esters, caffaldehydes A, B, and C, were discovered in Arabica beans, showcasing significant alpha-glucosidase inhibitory activity.

3 Sep 2025

Study reveals how type 2 diabetes directly alters the heart’s structure and energy systems

A new study from the University of Sydney has revealed how type 2 diabetes directly alters the heart’s structure and energy systems, offering vital insights into why people with diabetes are at greater risk of heart failure.

2 Sep 2025

Medicaid expansion boosts access to opioid use disorder treatment

Medicaid plays a key role for giving people with opioid-use disorder access to treatment, according to a Rutgers Health study.

2 Sep 2025

Hepatitis B immunity reduces diabetes risk across age groups

New research to be presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 September) and published in the journal Diagnostics shows that people with hepatitis B immunity induced by vaccination have a lower risk of developing diabetes of any kind.

2 Sep 2025

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Medical Condition News

Sacubitril/valsartan shows benefit over enalapril in heart failure caused by Chagas disease

Evolocumab fails to reduce vein graft disease after coronary artery bypass surgery

No clear benefit from surgical left atrial appendage occlusion in non-AF patients after valve surgery

Study finds sex differences in schizophrenia and bipolar disorder

Genetic variant disrupts brain’s cleanup crew increasing Alzheimer’s risk

Long-term benzodiazepine use linked to poor sleep quality in older adults

Novel vascularized cancer-on-a-chip model reflects the microenvironment of liver tumors

Flooding from Hurricane Sandy raises heart disease risk years later

Researchers uncover a promising new therapeutic target for Barth syndrome

Chronic stress and fatty diet disrupt brain-liver circuit leading to diabetes

Intravenous cangrelor provides rapid platelet inhibition in cardiogenic shock

Home-based hypertension care improves blood pressure control in rural South Africa

Early aspirin discontinuation safe after complete revascularization in acute MI

Playing joyful music helps ease motion sickness symptoms

Novel ablation approach improves outcomes in patients with persistent atrial fibrillation

Ablation methods equally effective for drug-resistant paroxysmal atrial fibrillation

Roasted Arabica coffee hides powerful antidiabetic molecules

Study reveals how type 2 diabetes directly alters the heart’s structure and energy systems

Medicaid expansion boosts access to opioid use disorder treatment

Hepatitis B immunity reduces diabetes risk across age groups

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

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