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Study links circulating short-chain fatty acids to type 2 diabetes risk

Short-chain fatty acids (SCFAs) serve as key signaling molecules linking gut microbiota and host health. Microbially produced SCFAs in the colon are generally acknowledged for their beneficial effects on cardiometabolic health, including enhancing insulin secretion, reducing plasma cholesterol and glucose levels, and controlling energy intake through the modulation of enteroendocrine hormones.

24 Jan 2025

Positive mental well-being can help maintain a physically active lifestyle

According to a recent study, the tendency to experience positive affectivity contributed to people being physically active or even increasing their activity during the COVID-19 restrictions.

24 Jan 2025

Breakthrough study targets tumor cell clusters to prevent metastasis

Certain tumor types do not remain at their point of origin but spread throughout the body and form metastases.

24 Jan 2025

Volunteering reduces loneliness in older adults

Researchers examine how social volunteering affects the social and emotional aspects of loneliness among older adults in China.

24 Jan 2025

Decades of DNA expansion linked to Huntington’s disease neurodegeneration

Researchers uncover how slow CAG repeat expansions in neurons drive Huntington’s disease over decades.

24 Jan 2025

Study finds successful treatment of childhood obesity lowers long-term health risks

Effective treatment of childhood obesity significantly lowers long-term health risks, including type 2 diabetes and hypertension, promoting better adult health.

24 Jan 2025

Study shows how physical activity can enhance brain function and prevent dementia

A study led by scientists at Rutgers University-New Brunswick has shown that specialized cells involved in how the body responds to insulin are activated in the brain after exercise, suggesting that physical activity may directly improve brain function.

23 Jan 2025

Harnessing the power of gamers to solve cancer's mysteries

Cancer is vicious. In 2025, it is expected to cause more than 618,000 U.S. deaths - nearly twice the combined populations of Merced and Modesto.

23 Jan 2025

Multi-omics approach identifies potential drug combinations for AML treatment

Acute myeloid leukaemia (AML) is mainly characterized by an increase in the number of myeloid cells in the bone marrow and a decrease in mature cells, accounting for 28% of leukaemia cases, with a five-year survival rate of only 30.5%.

23 Jan 2025

Researchers identify ferroptosis as driver of osteocyte death in melanoma metastasis

Melanoma, one of the most aggressive forms of skin cancer, often metastasizes to bones, causing severe bone loss, an increased risk of fractures, and significant pain.

23 Jan 2025

Uncertainty surrounds effects of puberty blockers and hormone therapy for gender dysphoria

Major uncertainties remain about the impact of puberty blockers and gender affirming hormone therapy on children and young people with gender related distress (gender dysphoria), making it impossible to determine conclusively whether they help or harm, find two pooled data analyses of the available evidence, published online in the Archives of Disease in Childhood.

23 Jan 2025

USF study: Pulmonary fibrosis after COVID-19 tends to get better

Pulmonary fibrosis is a rare, chronic disease that causes scarring in the lungs, making breathing difficult for people who suffer with it.

23 Jan 2025

Understanding the long-term effects of repetitive head hits in athletes

The impact makes us cringe-the sound of two helmets making contact during a football game, a player down on the field.

23 Jan 2025

Parental divorce in childhood tied to 61% higher stroke risk in older adults

Experiencing parental divorce in childhood is associated with a significantly higher risk of stroke in older adulthood, even after accounting for key risk factors such as income, depression, and diabetes.

23 Jan 2025

Research shows sharp growth in sedative and anxiety medication use disorders in youth

The prevalence of diagnosed disorders from recurrent use of sedative, hypnotic and antianxiety medications in adolescents and young adults has increased sharply since 2001, according to Rutgers Health researchers.

23 Jan 2025

Two-thirds of people with post-COVID-19 syndrome experience long-term effects

Two-thirds of people with post-COVID-19 syndrome have persistent, objective symptoms – including reduced physical exercise capacity and reduced cognitive test performances – for a year or more, with no major changes in symptom clusters during the second year of their illness, according to a new study published January 23rd in the open-access journal PLOS Medicine by Winfried Kern of Freiburg University, Germany, and colleagues.

23 Jan 2025

Non-industrialized diet improves health and reduces disease risk

Researchers have found that a newly developed diet inspired by the eating habits of non-industrialised societies can significantly reduce the risk of a number of chronic diseases – and are to share recipes with the public.

23 Jan 2025

Pomalidomide shows promise in enhancing immune responses in myeloma

A new editorial was published in Oncoscience's Volume 12 on January 14, 2025, titled "Pomalidomide improved immune profiles in myeloma."

23 Jan 2025

Study reveals abelacimab’s potential to improve anticoagulation safety for AFib patients

Abelacimab, a factor XI inhibitor, demonstrated a 62–69% reduction in major bleeding compared to rivaroxaban in atrial fibrillation patients at moderate-to-high stroke risk, with comparable safety and efficacy. While ischemic stroke rates were slightly higher, they were not statistically significant, warranting further phase 3 trials for confirmation.

23 Jan 2025

Metronomic chemotherapy offers hope for children with neuroblastoma

Neuroblastoma is the most common extracranial solid tumor in children, with nearly 50% of cases diagnosed at an advanced stage, often with metastatic disease.

23 Jan 2025