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New antibody-toxin conjugate designed to stimulate immune-mediated eradication of tumors

Researchers at The University of Texas MD Anderson Cancer Center have developed a novel antibody-toxin conjugate (ATC) designed to stimulate immune-mediated eradication of tumors.

25 Feb 2025

Using quorum sensing inhibitors as a novel approach to address antibiotic resistance

Pseudomonas aeruginosa is notorious for its role in food spoilage and infections, posing a significant threat to both food safety and human health.

25 Feb 2025

Why life expectancy gains in Europe stalled—and how some countries stayed ahead

Life expectancy gains in Europe slowed after 2011, with the COVID-19 pandemic further accelerating declines—while some countries maintained progress through sustained public health policies.

25 Feb 2025

Can coffee push back Parkinson’s? New study uncovers key genetic link

Higher coffee consumption is causally linked to delayed onset of Parkinson’s disease but does not affect disease risk or progression, according to a Mendelian randomization study.

25 Feb 2025

Water-only fasting boosts human growth hormone without weight loss

Fasting for 24 hours increases human growth hormone (HGH) levels independently of weight loss, with individuals with lower baseline HGH experiencing the most significant increases. The study suggests metabolic benefits from fasting, particularly for those with lower HGH levels.

25 Feb 2025

Breast cancer cases and deaths set to surge by 2050—are we prepared?

A global study finds that breast cancer cases will rise by 38% and deaths by 68% by 2050, with the highest incidence in Australia and New Zealand and worsening mortality in low-income countries.

25 Feb 2025

Discovery of new bat flu strain with potential to infect other species

Scientists have identified a novel influenza A virus (H18N12) in fishing bats in the Colombian Caribbean, revealing genetic reassortment events that impact viral adaptability and host transmission.

25 Feb 2025

Cooling treatment shows no benefits for preterm infants with hypoxic ischemic encephalopathy

Lowering the body temperature of preterm infants (born at 33 to 35 weeks of pregnancy) with hypoxic ischemic encephalopathy (HIE)-a type of brain damage caused by oxygen loss-offers no benefits over standard care, according to a study funded by the National Institutes of Health (NIH).

25 Feb 2025

Researchers identify key gut cells involved in diarrhea response

Researchers from the Organoid group at the Hubrecht Institute have found that specific gut cells, BEST4/CA7+ cells, regulate electrolyte and water balance in response to bacterial toxins that cause diarrhea.

25 Feb 2025

Researchers discover key signaling pathway involved in atherosclerotic plaques

CD8+ T cells accumulate in atherosclerotic plaques. LMU researchers identify a crucial signaling pathway - with therapeutic potential.

25 Feb 2025

Study reveals ferulic acid's potential in preventing colon cancer

Colon cancer continues to be one of the leading causes of cancer-related deaths worldwide, with poor dietary habits identified as a major risk factor.

25 Feb 2025

FGF21 hormone drives protein-specific appetite and reward in the brain

When faced with multiple food options and ultimately choosing one, the factors of that decision-making process may be more physiological than previously assumed.

25 Feb 2025

Using bioengineered materials to treat chemotherapy-induced oral lesions

A new research paper was published in Oncotarget, Volume 16, on February 18, 2025, titled "Leukopenia, weight loss and oral mucositis induced by 5-Fluorouracil in hamsters' model: A regenerative approach using electrospun poly(Lactic-co-Glycolic Acid) membrane."

25 Feb 2025

New research reveals how cell state affects leukemia progression

Myeloid leukaemias are among the most aggressive blood cancers and have low survival rates. Today, leukaemia patients undergo genetic analysis to identify mutations and select the most appropriate treatment.

25 Feb 2025

Advanced MRI uncovers lung abnormalities in children and teens with long COVID

An advanced type of MRI uncovers significant lung abnormalities in children and adolescents with long COVID, according to a new study published today in Radiology, a journal of the Radiological Society of North America .

25 Feb 2025

Women experience perimenopause symptoms much earlier than expected

More than half of women ages 30 to 35 are already suffering moderate to severe symptoms associated with menopause, yet most women are waiting decades before seeking treatment, new research from UVA Health and the Flo women's health app reveals.

25 Feb 2025

Researchers challenge previous understanding of tumor growth in NF-1

Despite what was previously thought, new research has shown that genetic changes alone cannot explain why and where tumors grow in those with genetic condition neurofibromatosis type 1 (NF-1).

25 Feb 2025

New mechanism uncovered to combat therapy-resistant cancer cells

One particular challenge in the treatment of cancer is therapy resistance. An international research team has now discovered a mechanism that opens up new treatment strategies for tumors in which conventional chemotherapeutic agents have reached their limits.

25 Feb 2025

Mass General Brigham study uncovers 16 novel Alzheimer's risk genes

Investigators from Mass General Brigham have conducted a multi-ancestry, whole genome sequencing association study of Alzheimer's disease and found evidence for 16 new susceptibility genes, expanding the study of Alzheimer's disease in underrepresented groups.

25 Feb 2025

Early pregnancy nutrition impacts child's motor development at age 5-6

A healthy diet in early pregnancy supports the child's motor development at the age of 5-6 years. Higher maternal body fat mass, on the other hand, has an adverse effect on the child's motor development.

25 Feb 2025