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Decades of research push cytomegalovirus vaccine closer to reality

Researchers review decades of progress in human cytomegalovirus (HCMV) vaccine development, emphasizing challenges, innovative platforms, and the critical need for effective prevention strategies.

6 Jan 2025

POCUS reduces emergency visits and improves pregnancy care

Published in Annals of Family Medicine, a University of Minnesota Medical School research team found that implementing point-of-care ultrasounds (POCUS) to assess the viability and gestational age of pregnancies in the first trimester enhanced care for pregnant patients and cut emergency visits by 81% for non-miscarrying patients.

6 Jan 2025

Newly identified genes may hold the key to understanding brain's response to PFAS

Per- and polyfluorinated alkyl substances (PFAS) earn their "forever chemical" moniker by persisting in water, soil and even the human brain.

6 Jan 2025

AI-based SCORPIO tool offers better cancer immunotherapy predictions

Doctors around the world may soon have access to a new tool that could better predict whether individual cancer patients will benefit from immune checkpoint inhibitors - a type of immunotherapy - using only routine blood tests and clinical data.

6 Jan 2025

Research highlights how a ketone body can enhance blood flow to the heart

Matthew Nystoriak, Ph.D., associate professor of biomedical research and translational medicine at Masonic Medical Research Institute (MMRI), has uncovered groundbreaking insights into heart health in a recent study titled, Myocardial Hyperemia via Cardiomyocyte Catabolism of β-Hydroxybutyrate.

6 Jan 2025

Early results of doxy PEP rollout show mixed impact on STIs

As health care services begin offering doxycycline to prevent bacterial sexually transmitted infections (STIs), real-world evidence demonstrates that the postexposure strategy, called doxy PEP, is reducing the rate of syphilis and chlamydia, but has had little to no effect on gonorrhea and needs close monitoring for signals of antibiotic resistance.

6 Jan 2025

NIH funding supports research into chronic pain following surgery

After surgery, pain is expected and often subsides within a few weeks. But for around 20% of patients, persistent pain may continue for months or even years after a procedure, impacting quality of life and putting patients at risk for opioid overuse.

6 Jan 2025

Glucarpidase shows promise in treating kidney toxicity from methotrexate

An FDA-approved medication called glucarpidase could serve as an antidote to kidney toxicity in patients receiving the chemotherapy drug methotrexate (MTX), according to a new study by investigators at Mass General Brigham.

6 Jan 2025

Study identifies how zinc deficiency can make drug-resistant bacteria vulnerable

Researchers at McMaster University have discovered a critical vulnerability in drug-resistant bacteria: zinc - or a lack thereof.

6 Jan 2025

Addressing loneliness in borderline personality disorder treatment

Loneliness is a key driver in the maintenance of borderline personality disorder (BPD), Harvard researchers argue. Thus, many patients cite increased social connection as a primary treatment goal.

6 Jan 2025

New biomarkers may offer a more sensitive approach for monitoring kidney health

Drug-induced kidney injury, or nephrotoxicity, is a common complication in clinical medicine that happens when drugs damage the kidneys.

6 Jan 2025

Anhedonia: The hidden psychological toll of deep endometriosis

Nearly 30% of women with deep endometriosis experience reduced pleasure sensitivity (anhedonia), linked to chronic pelvic pain, highlighting overlooked psychological consequences of this condition.

6 Jan 2025

Australian study warns of growing drug resistance in canine hookworms

Canine hookworms are becoming increasingly resistant to drugs across Australia, according to new research.

6 Jan 2025

Study unveils novel pathway triggering immune response to DNA damage

A research team from the University of California, Irvine has revealed a previously unknown mechanism that triggers an inflammatory immune response in cells when their DNA is damaged.

6 Jan 2025

Non-opioid pain relief proven more effective after wisdom teeth removal

A combination of acetaminophen (Tylenol) and ibuprofen (Advil, Motrin) controls pain after wisdom tooth removal better than opioids, according to a Rutgers Health study that could change how dentists treat post-surgical pain.

6 Jan 2025

Diet plays key role in shaping gut microbiome and health

A varied diet rich in vegetables is known to be healthy for one's well-being. Excessive consumption of meat, especially red meat, can lead to chronic and cardiovascular diseases.

6 Jan 2025

Puberty blockers and gender-affirming hormones rarely prescribed to transgender youth

Puberty blockers and gender-affirming hormones are rarely prescribed to U.S. transgender and gender diverse (TGD) adolescents, according to a new study from researchers at Harvard T.H. Chan School of Public Health, Harvard Pilgrim Health Care Institute, and FOLX Health.

6 Jan 2025

Investigating the impact of CircRNAs on cancer progression and drug resistance

The researcher has given an overview on the regulatory network of extracellular circRNAs in cancer and their impact on cancer drug resistance.

6 Jan 2025

Sugary beverages contribute to millions of diabetes and heart disease cases

A new study from researchers at the Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy at Tufts University, which published in Nature Medicine on January 6, estimates that 2.2 million new cases of type 2 diabetes and 1.2 million new cases of cardiovascular disease occur each year globally due to consumption of sugar-sweetened beverages.

6 Jan 2025

DoxyPEP reduces chlamydia and syphilis rates in routine care

A new study has found that rates of chlamydia and syphilis plummet among people prescribed doxycycline for sexually transmitted infection prevention in routine clinical care.

6 Jan 2025