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New structural insights pave the way for drug-resistant malaria therapies

Structural insights into a potent antimalarial drug candidate's interaction with the malaria parasite Plasmodium falciparum have paved the way for drug-resistant malaria therapies, according to a new study by researchers at Weill Cornell Medicine and Van Andel Institute.

18 Jan 2024

Oxford launches LEGACY03 trial to unravel age-related vaccine mysteries

Vaccines are the most effective way to prevent infectious diseases (NHS, 2023) however, people respond to them in different ways.

18 Jan 2024

Monell study: Unraveling the brain's wiring for fat and sugar cravings

Understanding why we overeat unhealthy foods has been a long-standing mystery. While we know food's strong power influences our choices, the precise circuitry in our brains behind this is unclear.

18 Jan 2024

Exploring substance use and stress among first responders during COVID-19

Considerable attention has focused on burnout and mental health of physicians and nurses on the frontline during the COVID-19 pandemic.

18 Jan 2024

Uncovering the cellular roots of spinocerebellar ataxia type 6

Researchers from McGill University, led by Professor Alanna Watt of the Department of Biology, have identified previously unknown changes in brain cells affected by a neurological disease.

18 Jan 2024

MIT study reveals consistent oscillation patterns across brain cortex layers

Throughout the brain's cortex, neurons are arranged in six distinctive layers, which can be readily seen with a microscope.

18 Jan 2024

St. Jude announces $13 million investment to expand the understanding of G-protein coupled receptors

St. Jude Children's Research Hospital today announced a nearly $13 million investment toward a new research collaboration with scientists at Columbia University, Duke University and Stanford University to expand the understanding of G-protein coupled receptors (GPCR), which are vital proteins that impact human health and disease.

18 Jan 2024

ARCHA at Aston University secures £400,000 to recruit four PhD students for dementia research

The Aston Research Centre for Health in Ageing (ARCHA) at Aston University has received £400,000 in funding to recruit four PhD students for a dementia research programme.

18 Jan 2024

New insights into how prenatal exposure to organophosphate esters affects a child's growth

Organophosphate esters, commonly used as substitutes for brominated flame retardants, are increasingly present in various environmental media due to their use in consumer products.

18 Jan 2024

Children battling meningitis face lifelong disability, study finds

One in three children who suffer from bacterial meningitis live with permanent neurological disabilities due to the infection.

18 Jan 2024

Understanding antimicrobial resistance in hospital-acquired pneumonia

New research has been published that identifies positive steps towards a better understanding of antimicrobial resistance (AMR), specifically in hospital-acquired pneumonia (HAP).

18 Jan 2024

Morphine shows potential as effective cough therapy for pulmonary fibrosis, study finds

The efficacy of the controlled release of low-dose morphine as treatment against that of a placebo in idiopathic pulmonary fibrosis.

18 Jan 2024

How do SCFAs modulate cardiometabolic risk in normal-weight adults?

How SCFAs modulate cardiometabolic disease risk by interacting with an individual's adiposity parameters and diet.

18 Jan 2024

Combined effect of poverty and inflammation on mortality is worse than expected from separate effects, study reports

Researchers investigated whether the combination of chronic inflammation and poverty synergistically increases the 15-year risk of mortality from all causes, heart disease, and cancer in American adults aged 40 and older.

18 Jan 2024

Short strands of toxic RNAs contribute to brain cell death and DNA damage in Alzheimer's

Alzheimer's disease, which is expected to have affected about 6.7 million patients in the U.S. in 2023, results in a substantial loss of brain cells.

18 Jan 2024

Age, ethnicity, and deprivation linked to lower COVID-19 vaccination rates in the UK

The association between under-vaccination against SARS-CoV-2 and COVID-19 outcomes.

18 Jan 2024

The role of glucose in inducing tolerance to amphotericin B for fungal meningitis treatment

Researchers investigate the mechanism responsible for amphotericin B tolerance of Cryptococcus neoformans.

18 Jan 2024

Mathematical modeling demonstrates efficacy of combinational drug therapy for breast cancer treatment

Researchers use a mathematical model to assess the efficacy of a new combinational therapy of AZD9496 and palbociclib for breast cancer treatment.

18 Jan 2024

New bioengineered strategy shows potential for treating ulcerative colitis

By taking advantage of mechanisms that allow cancer cells to evade immune attack, UT Southwestern Medical Center researchers have developed a new strategy in animal models that has potential for treating ulcerative colitis.

17 Jan 2024

OCD patients may have higher risk of death from both natural and unnatural causes

People with obsessive-compulsive disorder (OCD) may have an increased risk of death from both natural and unnatural causes than those without the disorder, finds a study from Sweden published by The BMJ today.

17 Jan 2024

Medical Research News

New structural insights pave the way for drug-resistant malaria therapies

Oxford launches LEGACY03 trial to unravel age-related vaccine mysteries

Monell study: Unraveling the brain's wiring for fat and sugar cravings

Exploring substance use and stress among first responders during COVID-19

Uncovering the cellular roots of spinocerebellar ataxia type 6

MIT study reveals consistent oscillation patterns across brain cortex layers

St. Jude announces $13 million investment to expand the understanding of G-protein coupled receptors

ARCHA at Aston University secures £400,000 to recruit four PhD students for dementia research

New insights into how prenatal exposure to organophosphate esters affects a child's growth

Children battling meningitis face lifelong disability, study finds

Understanding antimicrobial resistance in hospital-acquired pneumonia

Morphine shows potential as effective cough therapy for pulmonary fibrosis, study finds

How do SCFAs modulate cardiometabolic risk in normal-weight adults?

Combined effect of poverty and inflammation on mortality is worse than expected from separate effects, study reports

Short strands of toxic RNAs contribute to brain cell death and DNA damage in Alzheimer's

Age, ethnicity, and deprivation linked to lower COVID-19 vaccination rates in the UK

The role of glucose in inducing tolerance to amphotericin B for fungal meningitis treatment

Mathematical modeling demonstrates efficacy of combinational drug therapy for breast cancer treatment

New bioengineered strategy shows potential for treating ulcerative colitis

OCD patients may have higher risk of death from both natural and unnatural causes

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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