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Monocytic tRNA fragments play key role in poststroke immune reactions

Sebastian Lobentanzer of Goethe University, Frankfurt, has been studying small RNA dynamics in various contexts using bioinformatic methods. Recently, small RNAs have become more and more interesting for researchers, primarily because of their extensive regulatory functions.

11 Dec 2020

High expression of VRK1 protein can reduce survival in neuroblastoma patients

Researchers from the Departments of Cell Biology and Medical Physiology at the University of Seville have identified that a high expression of the human protein VRK1 is associated with tumour aggressiveness and low survival among neuroblastoma patients.

11 Dec 2020

Scientists use human stem cells and bioengineered scaffold to build whole functioning thymus

Researchers at the Francis Crick Institute and University College London have rebuilt a human thymus, an essential organ in the immune system, using human stem cells and a bioengineered scaffold.

11 Dec 2020

New analysis method could pave the way for important breakthroughs in immunotherapy

In a new study, researchers at Uppsala University have been able to show differences in how Rituximab, a monoclonal antibody drug, interacts with the blood of healthy individuals compared to patients with chronic lymphatic leukemia. This has awakened hopes that this analysis method could pave the way for important breakthroughs in immunotherapy research and treatment.

11 Dec 2020

COVID-19 lockdown causes record drop in CO2 emissions for 2020

Carbon dioxide emissions fell by a record 2.4 billion in 2020, according to researchers at the UEA, University of Exeter, and the Global Carbon Project.

11 Dec 2020

Genetic differences play a vital role in early diagnosis of Alzheimer's disease

The two clinically used methods for detecting amyloid pathology in Alzheimer's disease do not give unambiguous results, with the risk of incorrect or delayed care interventions.

11 Dec 2020

SARS-CoV-2 genetic material can be reliably detected in self-collected saliva samples

Researchers at Memorial Sloan Kettering Cancer Center (MSK) have found that SARS-CoV-2 genetic material can be reliably detected in self-collected saliva samples at a rate similar to that of nasopharyngeal and oropharyngeal swabs.

11 Dec 2020

Detailed simulations reveal new information on sickle cell disease

Although there has yet to be a cure for sickle cell disease, researchers recently created detailed simulations on the Comet system at the San Diego Supercomputer Center (SDSC) showing how these stiff red blood cells flow through blood vessels, deforming and colliding along the way.

11 Dec 2020

Study shows how coronavirus uses spike proteins to infiltrate cells of different animals

Humans, followed by ferrets and to a lesser extent cats, civets and dogs are the most susceptible animals to SARS-CoV-2 infection, according to an analysis of ten different species carried out by researchers at the Centre for Genomic Regulation (CRG), based in Barcelona.

11 Dec 2020

Rapid lateral flow immunoassay enables fluorescence detection of SARS-Cov-2 RNA

The COVID-19 pandemic has highlighted the need for rapid and accurate nucleic acid detection at the point of care. To meet this need, scientists from the Suzhou Institute of Biomedical Engineering and Technology have developed a novel amplification-free rapid SARS-CoV-2 nucleic acid detection platform based on hybrid capture fluorescence immunoassay (HC-FIA).

11 Dec 2020

Scientist pinpoints genes that promote the growth of prostate cancer cells

Research by a University of Georgia scientist sheds light on how two genes factor into prostate cancer cells becoming resistant to treatment, providing a potential new target for therapeutics.

11 Dec 2020

Study sheds new light on reflexive behaviors

When you touch a hot stove, your hand reflexively pulls away; if you miss a rung on a ladder, you instinctively catch yourself.

10 Dec 2020

Researchers find new method for safe and effective delivery of medicines to the lungs

Investigators at Rutgers Cancer Institute of New Jersey and Rutgers New Jersey Medical School recently identified a new method for safe and effective delivery of medicines to the lungs that can be used for multiple clinical applications, potentially including aerosol vaccination.

10 Dec 2020

Melatonin and its metabolites promote the formation of long-term memories

Researchers at Tokyo Medical and Dental University in Japan show that melatonin and its metabolites promote the formation of long-term memories in mice and protect against cognitive decline.

10 Dec 2020

A new model for assessing kidney function in cancer patients

Cold Spring Harbor Laboratory scientists have developed a new model for assessing kidney function in cancer patients as part of an international collaboration that involved contributions from the United Kingdom and Sweden.

10 Dec 2020

Study connects specific foods to later-in-life cognitive acuity

The foods we eat may have a direct impact on our cognitive acuity in our later years. This is the key finding of an Iowa State University research study spotlighted in an article published in the November 2020 issue of the Journal of Alzheimer's Disease.

10 Dec 2020

MUSC cancer researcher named as a 2020 fellow of National Academy of Innovators

In recognition of her spirit of innovation and the lasting impact of her work on cancer patients, MUSC Hollings Cancer Center researcher Nancy Klauber-DeMore, M.D., has been named as a 2020 fellow of the National Academy of Innovators, the organization announced Dec. 8.

10 Dec 2020

New computer algorithm could end misidentification of cancer cells in laboratories

Researchers from the University of Kent have developed a computer algorithm that can identify differences in cancer cell lines based on microscopic images, a unique development towards ending misidentification of cells in laboratories.

10 Dec 2020

Antiepileptic drug reduces early signs of clinical dysfunction in people with ALS

The antiepileptic drug ezogabine reduced pathologic excitability of cortical and spinal motor neuron cells that are early signs of clinical dysfunction in people with amyotrophic lateral sclerosis (ALS), according to a study conducted by the Neurological Clinical Research Institute of Massachusetts General Hospital.

10 Dec 2020

Longer nocturnal respiratory events in OSA patients have an effect on the heart

Longer nocturnal respiratory events in patients with obstructive sleep apnoea (OSA) cause higher immediate heart rate variability, and greater changes in beat-to-beat intervals are associated with reduced daytime alertness, according to new research from the University of Eastern Finland.

10 Dec 2020