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Novel global cooperative phenomena of cell interactions discovered in cervical cancer cells

A Japanese research team has discovered a novel global cooperative phenomena of cell interactions in cervical cancer cells. Their findings suggest that the cells are metabolically connected in a functional network.

25 Mar 2025

Targeting PCSK9 and APOA4 for the treatment of TMAO-induced cholelithiasis

Cholesterol synthesis and gallstone formation are promoted by trimethylamine-N-oxide (TMAO), a derivative of trimethylamine, which is a metabolite of gut microbiota.

25 Mar 2025

Cryptotanshinone could be a promising therapeutic option for Kawasaki disease

Announcing a new publication for Acta Materia Medica journal. Kawasaki disease (KD) is a form of vasculitis that affects primarily children and can lead to severe cardiovascular complications.

25 Mar 2025

Simple changes in eating habits could help fight obesity

Obesity is linked to numerous health complications, including diabetes, cardiovascular disease, and fatty liver disease.

25 Mar 2025

CDC study identifies leading culprits of foodborne illness

Researchers from the CDC and Colorado School of Public Health estimate that seven major pathogens caused 9.9 million foodborne illnesses in the US in 2019. Norovirus led illness and hospitalization counts, while Salmonella caused the most deaths.

25 Mar 2025

Blocking an inflammatory receptor in the retinas of aging mice improves retinal health

A new research paper was published in Aging (Aging-US) on January 31, 2025, in Volume 17, Issue 2, titled "Cysteinyl leukotriene receptor 1 modulates retinal immune cells, vascularity and proteolytic activity in aged mice."

25 Mar 2025

New brain metabolism model reveals key targets for reversing aging

The most comprehensive model of the brain’s metabolism, incorporating more than 16,800 biochemical interactions, has identified key targets to reverse the age-related decline in brain function.

25 Mar 2025

New insights into therapy resistance in breast cancer

A new review was published in Oncotarget, Volume 16, on March 13, 2025, titled "Signaling pathway dysregulation in breast cancer."

25 Mar 2025

Scientists develop universal vaccine targeting multiple coronaviruses

Sugar coatings aren't only for candies; they also help viruses, like the ones that cause COVID-19, hide from their hosts' immune system.

25 Mar 2025

High-salt diet induces depression-like symptoms in mice

A new study published in The Journal of Immunology found that a high-salt diet (HSD) induces depression-like symptoms in mice by driving the production of a protein called IL-17A.

25 Mar 2025

Study links kynurenine pathway to adolescent depression

Depression is a mental health condition that affects 280 million people worldwide. It is twice as common in women than men and this pattern starts to develop during adolescence.

25 Mar 2025

Research identifies pressure-sensing protein behind gut motility

After every meal, the intestines perform an action called peristalsis - moving food through their hollow interiors with coordinated contractions and relaxations of the smooth muscle.

25 Mar 2025

Understanding the role of iron-dependent ferroptosis in immune suppression

Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression.

24 Mar 2025

Sperm viability boosted in IVF with glycan technology

The success of in vitro fertilization depends on many factors, one of which is sperm viability. A recent study from the University of Illinois Urbana-Champaign documents a new way to select viable sperm and prolong their viability in the laboratory, reducing one source of variability during the process.

24 Mar 2025

New brain circuit involved in motion sickness could help improve metabolic health

Motion sickness is a very common condition that affects about 1 in 3 people, but the brain circuits involved are largely unknown. In the current study published in Nature Metabolism, researchers at Baylor College of Medicine, the University of Texas Health Science Center at Houston and the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital describe a new brain circuit involved in motion sickness that also contributes to regulating body temperature and metabolic balance.

24 Mar 2025

Study links type 2 diabetes to weakened reward signals in the brain

The high comorbidity of type 2 diabetes (T2D) with psychiatric or neurodegenerative disorders points to a need for understanding what links these diseases.

24 Mar 2025

Scientists uncover role of m6A in prostate cancer progression

Scientists at the UCLA Health Jonsson Comprehensive Cancer Center and the University of Toronto have revealed how a tiny chemical modification in RNA, known as m6A, plays a critical role in the progression of prostate cancer, including driving some of its most dangerous forms of the disease.

24 Mar 2025

Researchers develop TIM-3 decoy to enhance CAR-T therapy effectiveness for B-ALL tumors

B-cell Acute Lymphoblastic Leukemia (B-ALL) is a life-threatening and highly aggressive form of blood cancer. It is the most common childhood cancer, making up 35% of pediatric cancer cases, but it can affect people of any age.

24 Mar 2025

Smell-based test taken at home could predict cognitive impairment in older adults

When it comes to early detection of cognitive impairment, a new study suggests that the nose knows. Researchers from Mass General Brigham developed olfactory tests-in which participants sniff odor labels that have been placed on a card-to assess people's ability to discriminate, identify and remember odors.

24 Mar 2025

New insights into how sleep reorganizes neuronal activity for better memory

Why is sleep so important for learning and memory? Neuroscientists from the Csicsvari group at the Institute of Science and Technology Austria (ISTA) provided new insight into this essential function by monitoring neuronal activity in rat brains for up to 20 hours of sleep following spatial learning.

24 Mar 2025