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Scientists uncover new obesity genes that reshape understanding of weight and disease risk

Researchers identified five previously unknown genes linked to obesity by analyzing rare protein-truncating variants across six ancestries. The study reveals how rare and common genetic factors combine to influence BMI and related diseases like diabetes and heart failure.

2 Nov 2025

Columbia researchers report first successful pregnancy using AI-guided sperm recovery method

Researchers at the Columbia University Fertility Center reported the first successful pregnancy using an AI-guided method they developed to recover sperm in men with azoospermia, in which ejaculate contains little or no sperm.

31 Oct 2025

Life expectancy gains are slowing

Research shows life expectancy growth is slowing, with significant implications for health policies and individual planning in high-income nations.

31 Oct 2025

Massive cross-ancestry study explains why obesity risks differ around the world

A massive cross-ancestry genetic study involving over 839,000 adults identified 13 genes linked to obesity, including five never before associated with the condition. The findings highlight how global genetic diversity can uncover new biological pathways and potential treatment targets for obesity.

31 Oct 2025

Common viruses sharply raise heart attack and stroke risk, major global review shows

In the largest synthesis to date, researchers reviewed 155 studies linking viral infections, including influenza, SARS-CoV-2, HIV, hepatitis C, and shingles, to increased risks of coronary heart disease, stroke, and heart failure. The findings highlight viral infection prevention and vaccination as underappreciated strategies for cardiovascular protection.

30 Oct 2025

Study confirms PSA screening improves survival and safety

After 23 years of follow-up, the European Randomized Study of Screening for Prostate Cancer (ERSPC) confirmed a 13% lower prostate cancer mortality with PSA testing and an improved harm–benefit ratio over time. Risk-based screening could sustain mortality gains while reducing overdiagnosis and unnecessary treatment.

30 Oct 2025

Football hits leave lasting brain changes

Recent MRI research reveals how repeated football head impacts reshape brain structures, offering insights into chronic traumatic encephalopathy (CTE) risk.

30 Oct 2025

Diabetes remission possible with GLP-1 drugs, Italian study confirms

In a large real-world Italian cohort, GLP-1 receptor agonist therapy led to measurable rates of type 2 diabetes remission, depending on how remission was defined. The most pragmatic definition (Remission 3) was linked to improved glycemia, weight, and a lower risk of microvascular and cardiovascular events.

29 Oct 2025

Eating habits tied to Parkinson’s risk: sweets and processed meats raise odds, fruit lowers them

In a large Italian case-control study, researchers identified data-driven dietary patterns linked to Parkinson’s disease risk. Diets rich in sweets, red and cured meats were associated with higher odds of PD, while fruit, especially citrus, was protective.

29 Oct 2025

Aligning your body clock may protect your heart and metabolism, says AHA

A new American Heart Association scientific statement highlights how maintaining circadian health through regular sleep, light exposure, meal timing, and exercise may reduce cardiometabolic disease risk. Disrupting these daily rhythms can impair glucose regulation, blood pressure, and cardiovascular function.

29 Oct 2025

Retaining gonad function could be a potent strategy to fight late-life frailty

Frailty threatens older individuals because it increases their vulnerability to detrimental health outcomes, such as falling, longer hospitalization, or even shortened life expectancy.

29 Oct 2025

Hydroxytyrosol from olives shows new promise as a brain-protective compound

This review highlights hydroxytyrosol's role as a neuroprotective agent, activating key pathways for mental and vascular health through olive-derived compounds.

29 Oct 2025

Women gain stronger heart protection from exercise than men, study reveals

Researchers analyzing over 85,000 UK Biobank participants found that women gain greater cardiovascular benefits from physical activity than men, needing only half the exercise to achieve similar reductions in coronary heart disease and mortality risk. The study underscores the importance of sex-specific guidelines for CHD prevention.

28 Oct 2025

AI-powered LifeClock forecasts diseases years before symptoms appear

Researchers have developed LifeClock, an AI-driven biological clock trained on over 24 million electronic health records to estimate biological age across the human lifespan. The model accurately predicts disease risk years in advance, revealing distinct developmental and aging processes.

28 Oct 2025

E. coli in retail meat linked to thousands of urinary infections

Research reveals a significant link between E. coli in meat and urinary tract infections, particularly in vulnerable communities in Southern California.

28 Oct 2025

Obesity’s health risks shift with age and sex, new genetic study reveals

Using a new time-resolved Mendelian randomization approach in over 360,000 UK Biobank participants, Karlsson et al. revealed that the causal impact of obesity changes across life, with distinct age- and sex-specific risk patterns for diabetes, heart disease, atrial fibrillation, and osteoarthritis.

27 Oct 2025

Can cheese help prevent dementia? Japanese researchers say it might

Older Japanese adults who ate cheese at least once a week had a 21–24% lower risk of developing dementia over three years. The association remained significant even after adjusting for lifestyle and socioeconomic factors, suggesting a modest but meaningful protective effect.

27 Oct 2025

Study finds bright nights raise risk for stroke and heart failure in adults over 40

A large UK Biobank study found that higher night-time light exposure is linked to significantly greater risks of coronary artery disease, stroke, heart failure, and other cardiovascular conditions. The findings suggest maintaining darker nights and adequate daytime light could support heart health.

26 Oct 2025

What Britain’s post-war sugar rationing teaches us about long-term heart health

A BMJ study found that individuals exposed to sugar rationing during their first 1,000 days of life had significantly lower risks of heart attack, stroke, and heart failure in adulthood. Early-life sugar restriction was linked to a 2.5-year delay in cardiovascular disease onset, suggesting long-term benefits for heart health.

26 Oct 2025

Breakthrough combo therapy lowers death risk in recurrent prostate cancer

Men whose prostate cancer returns after surgery or radiation therapy may now benefit from a new drug combination shown in clinical trials to cut the risk of death by more than 40%.

23 Oct 2025