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Mount Sinai study provides a mechanistic explanation for variations in individual responses to drugs

Mount Sinai researchers have shown for the first time that a person's beliefs related to drugs can influence their own brain activity and behavioral responses in a way comparable to the dose-dependent effects of pharmacology.

3 Jan 2024

Existing beta blocker investigated as novel sickle cell therapy

A beta blocker typically used to treat heart problems, hemangioma, migraines and anxiety could be a new therapeutic for patients with sickle cell disease. Researchers led by Ankit A. Desai, MD, associate professor of medicine at the Krannert Cardiovascular Research Center (KCVRC) at Indiana University School of Medicine, have been awarded a $3 million grant by the U.S. Department of Defense to evaluate the efficacy of this drug.

3 Jan 2024

Hybrid immunity's role in curbing COVID-19: Canadian study sheds light on vaccine-infection synergy

Study evaluates the impact of hybrid immunity on SARS-CoV-2 antibody levels in Canadian adults, revealing that hybrid immunity, combining vaccination and recovery from infection, significantly reduces COVID-19 morbidity and mortality.

2 Jan 2024

New Pfizer/BioNTech vaccine variant shows enhanced protection against COVID-19 hospitalization

Study demonstrates that the BNT162b2 SARS-CoV-2 XBB1.5 variant-modified vaccine significantly reduces the risk of COVID-19-related hospitalizations and ambulatory visits, outperforming previous vaccine versions in the face of evolving virus strains.

2 Jan 2024

Microbial decoration enhances drug delivery specificity and safety

Announcing a new publication for Acta Materia Medica journal. Microorganisms are mostly distributed on the surface of our skin and intestines and have crucial roles in physiologic and metabolic processes, such as digestion and immunity, which are closely related to diseases.

29 Dec 2023

MHRA provides 5 festive top tips for people taking medicines or using medical devices

Christmas and New Year is a time when we particularly want to keep well and stay safe. The Medicines and Healthcare products Regulatory Agency (MHRA) has set out 5 festive top tips for people taking medicines or using medical devices.

21 Dec 2023

The year in opioid settlements: 5 things you need to know

This year, about $1.5 billion has landed in state and local government coffers from court settlements made with more than a dozen companies that manufactured, sold, or distributed prescription painkillers and were sued for their role in fueling the opioid crisis.

21 Dec 2023

Deep learning unlocks new antibiotic classes, revolutionizing the fight against resistance

A Nature journal study employs deep learning to analyze chemical sub-structures, leading to the discovery of new structural classes of antibiotics, showcasing the potential of AI in accelerating antibiotic development.

20 Dec 2023

Diabetes drug may help women avoid weight gain after quitting smoking

The diabetes drug dulaglutide (Trulicity) may significantly lower a woman's risk of substantial weight gain after she has given up smoking, finds a secondary analysis of clinical trial data, published in the open access journal BMJ Nutrition Prevention & Health.

19 Dec 2023

New study challenges "gold standard" opioid treatment for cancer pain

Researchers examining the data on opioids for pain caused by cancer have found surprisingly large gaps in evidence regarding the true benefits of these medicines for cancer pain.

18 Dec 2023

New vaccine strategy targets SARS-CoV-2's stable S2 subunit, offering broad protection against evolving variants

Study presents a new SARS-CoV-2 S2 subunit vaccine that elicits strong antibody responses against various sarbecovirus strains, including challenging variants like XBB.1.5, demonstrating its potential as a broadly effective and stable vaccine option.

18 Dec 2023

New study casts doubt on effectiveness of opioids for cancer pain

The world's largest review on opioid medicines for cancer pain has found it is unclear whether some commonly used opioid medicines are better than a placebo and suggests that non-opioid medicines, including aspirin, may be as effective as opioids.

18 Dec 2023

‘They see a cash cow’: Corporations could consume $50 billion of opioid settlements

The marketing pitches are bold and arriving fast: Invest opioid settlement dollars in a lasso-like device to help police detain people without Tasers or pepper spray.

18 Dec 2023

New study shows XBB.1.5 COVID-19 vaccine significantly reduces hospitalizations and ICU admissions in older adults

Study evaluates the effectiveness of the XBB.1.5 COVID-19 vaccine in reducing hospitalizations and ICU admissions among vaccinated adults aged 60 and over in the Netherlands, showing a 70.7% effectiveness against hospitalization and 73.3% against ICU admission.

17 Dec 2023

New AI framework can rapidly identify new use cases for existing therapeutics

Scientists at Klick Applied Sciences have created an artificial intelligence framework that can rapidly identify new use cases for existing therapeutics, according to findings presented Friday at the NeurIPS conference that could greatly improve the drug repurposing process and transform the pharmaceutical industry.

15 Dec 2023

Blueprint Medicines announces approval of AYVAKYT for treatment of ISM patients in Europe

Blueprint Medicines Corporation today announced the European Commission has approved AYVAKYT® (avapritinib) for the treatment of adult patients with indolent systemic mastocytosis (ISM) with moderate to severe symptoms inadequately controlled on symptomatic treatment. AYVAKYT is the first and only approved therapy for people living with ISM in Europe.

15 Dec 2023

New dry powder aerosol COVID-19 vaccine shows promise against multiple virus strains

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Pharmaceutical News

Mount Sinai study provides a mechanistic explanation for variations in individual responses to drugs

Existing beta blocker investigated as novel sickle cell therapy

Hybrid immunity's role in curbing COVID-19: Canadian study sheds light on vaccine-infection synergy

New Pfizer/BioNTech vaccine variant shows enhanced protection against COVID-19 hospitalization

Microbial decoration enhances drug delivery specificity and safety

MHRA provides 5 festive top tips for people taking medicines or using medical devices

The year in opioid settlements: 5 things you need to know

Deep learning unlocks new antibiotic classes, revolutionizing the fight against resistance

Diabetes drug may help women avoid weight gain after quitting smoking

New study challenges "gold standard" opioid treatment for cancer pain

New vaccine strategy targets SARS-CoV-2's stable S2 subunit, offering broad protection against evolving variants

New study casts doubt on effectiveness of opioids for cancer pain

‘They see a cash cow’: Corporations could consume $50 billion of opioid settlements

New study shows XBB.1.5 COVID-19 vaccine significantly reduces hospitalizations and ICU admissions in older adults

New AI framework can rapidly identify new use cases for existing therapeutics

Blueprint Medicines announces approval of AYVAKYT for treatment of ISM patients in Europe

New dry powder aerosol COVID-19 vaccine shows promise against multiple virus strains

Intranasal COVID-19 vaccine shows promise in reducing severe symptoms

UH researchers secure NIH grant to tackle buprenorphine's dental side effects

How safe are GLP-1R agonists in early pregnancy?

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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