Cannabinoid

Cannabinoids are a group of terpenophenolic compounds present in Cannabis (''Cannabis sativa'') and occur naturally in the nervous and immune systems of animals.

What are Cannabinoids?

Cannabinoids are naturally occurring compounds found in the Cannabis sativa plant. Of over 480 different compounds present in the plant, only around 66 are termed cannabinoids.

Synthetic and Patented Cannabinoids

Pharmacology of Cannabinoid Receptors

The Immunological Effects of Cannabinoids

Crystal Structure of the Human Cannabinoid Receptor CB2

A Failed Cannabis Hair Test - How Topical Application Results in Cannabinoid Incorporation

Does CBD Oil Work for Arthritis Pain?

Latest Cannabinoid News and Research

FDA approved drugs active against COVID-19

With the rapid spread of the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) throughout the world, causing the current COVID-19 pandemic, there is an urgent need for new antivirals and vaccines to combat its spread. The current study published on the preprint server bioRxiv in June 2020 shows some of the results of the extensive repurposing of already FDA-approved drugs.

23 Jun 2020

Advance your analysis of cannabis with Restek’s new Cannabidivarinic Acid standard

Cannabidivarinic Acid is a non-psychoactive cannabinoid reported to have anti-inflammatory properties.

From Restek Corporation 19 Jun 2020

Determining Cannabinoids in Marijuana-Infused Edibles

Marijuana-infused edibles or medibles have increased immensely over the last 10 years. With products such as brownies and gummy bears infused with marijuana, it is more important now than ever to test these cannabis-related products.

From Pittcon 12 Jun 2020

Study assesses the acute impact of cannabis among real-world users

Smoking high-potency marijuana concentrates boosts blood levels of THC more than twice as much as smoking conventional weed, but it doesn't necessarily get you higher, according to a new study of regular users published today by University of Colorado Boulder researchers.

10 Jun 2020

GMU researchers studying effect of cannabidiol on exosome release

Fatah Kashanchi, Professor, Laboratory of Molecular Virology, School of Systems Biology, and Lance Liotta, Co-Director, Applied Proteomics and Molecular Medicine, are working to mitigate virally driven HIV pathenogenesis in the central nervous system.

5 Jun 2020

Study explores impact of simultaneous alcohol and cannabis usage on unborn children

An unforeseen consequence of normalization of marijuana use is that adolescents and adults of childbearing age are increasingly engaged in a practice of Simultaneous Alcohol and Cannabinoid (SAC) use, or co-ingestion.

28 Apr 2020

Teen marijuana use associated with insomnia later on

Smoke a lot of weed as a teenager, and when you reach adulthood you'll be more likely to have trouble falling or staying asleep, according to a new University of Colorado Boulder study of more than 2,000 twins.

31 Mar 2020

Accurate and informative labeling of CBD products is a critical public health issue

The need for accurate and informative labeling of hemp and hemp-derived cannabidiol (CBD) products is a critical public health issue.

25 Mar 2020

Mapping the cannabis genome to improve agriculture and human health

Unlocking the full potential of cannabis for agriculture and human health will require a co-ordinated scientific effort to assemble and map the cannabis genome, says a just-published international study led by University of Saskatchewan researchers.

25 Mar 2020

Cannabidiol helps fight antibiotic-resistant bacteria

Since the discovery of penicillin in 1928 by Sir Alexander Fleming, antibiotics have saved millions of lives from fatal infections world-wide. However, with time bacteria have developed mechanisms to escape the effects of antibiotics - they have become resistant.

24 Mar 2020

Using cannabinoids for management of acute pain

A new systematic review and meta-analysis showed a small but significant reduction in subjective pain scores for cannabinoid treatment compared to placebo in patients experiencing acute pain.

23 Mar 2020

Why is the tobacco industry supporting wider access to medical cannabis?

A new study published in the BMJ reveals disturbing connections between organizations and groups that are lobbying for broader access to medical cannabis and those who are fighting for the legalization of recreational cannabis. This raises questions as to the reasons behind the industry’s support for measures that will make it easier for patients to gain access to medical cannabis – is it because of the knowledge that by so doing, they will also be able to market the drug for recreational use in the UK?

18 Mar 2020

Cannabinoid 1 receptor expression displays sexually dimorphic pattern in the mouse brain

A major challenge in neuroscience lies in understanding how molecular and circuit differences in the brain synergistically contribute to sex differences in behavioral phenotypes. Sex differences in the brain may arise from the identity, distribution and relative abundance of cell types.

17 Mar 2020

How cannabis interacts with medications

A new practice guideline published in the journal CMAJ in February 2020 describes five types of drug interactions possible with the use of cannabis. Cannabis is a plant-derived drug containing the psychoactive ingredient delta-9-tetrahydrocannabinol (THC) and non-psychoactive cannabidiol (CBD). These cannabinoids are broken down by the liver enzymes cytochrome P450 C(YP)34A, and CYP2CC9.

2 Mar 2020

Five things to know about drug interactions with cannabinoids

A practice article provides 5 things to know on how drugs can interact with cannabinoids in CMAJ.

2 Mar 2020

Cases of poisoning attributed to manipulated cannabidiol liquids in e-cigarettes

The health risks of e-cigarettes have come into focus after the deaths of several “vapers” due to lung injury in the USA recently.

27 Feb 2020

McMaster researchers identify antibacterial compound made by cannabis plants

McMaster University researchers have identified an antibacterial compound made by cannabis plants that may serve as a lead for new drug development.

26 Feb 2020

Common human gene variant linked to THC reward in adolescent females

A common variation in a human gene that affects the brain's reward processing circuit increases vulnerability to the rewarding effects of the main psychoactive ingredient of cannabis in adolescent females, but not males, according to preclinical research by Weill Cornell Medicine investigators.

12 Feb 2020

Study provides important insight into the recent lung intoxication epidemic

A new study published on 24 January 2020 in the journal Toxics provides important insight into the recent lung intoxication epidemic referred to as "e-cigarette or vaping product use-associated lung injury" (EVALI).

24 Jan 2020

Early vaping illness cases linked to vaping products containing vitamin E acetate

A new study published in January 2020 in the journal Toxics reports that a complete analysis of the products used by patients who fell ill after using vaping products shows one component standing out – vitamin E acetate (VEA). This was the outstanding component found in e-cigarette liquids containing cannabis compounds, but not in the nicotine-containing vaping liquids.

23 Jan 2020