Crohn's Disease News and Research

Latest Crohn's Disease News and Research

People with IBD accumulate more fecal microplastics, study finds

Microplastics -; tiny pieces of plastic less than 5 mm in length –– are everywhere, from bottled water to food to air. According to recent estimates, people consume tens of thousands of these particles each year, with unknown health consequences.

22 Dec 2021

A new approach for drugs to be more effective against inflammatory bowel disease

Biomedical scientists at the University of California, Riverside, propose a way for drugs to be more effective against inflammatory bowel disease, or IBD, in which the intestine undergoes inflammation.

18 Dec 2021

Researchers mapping the extent of IBD in the UK are seeking people's help

Scientists mapping the extent of Inflammatory Bowel Disease (IBD) in the UK are asking the public to help. Crohn's Disease and Ulcerative Colitis are the two main forms of IBD and affect more than 500,000people in theUK.

1 Dec 2021

People taking immunosuppressant produce weaker, shorter-lived antibodies after COVID-19 vaccination

People who received two doses of the Pfizer COVID-19 vaccine while on TNF inhibitors -; a class of immunosuppressants used to treat rheumatoid arthritis and other autoimmune conditions -; generated less powerful and shorter-lived antibodies against the virus that causes COVID-19 than healthy people and those on other kinds of immunosuppressants, according to a study by researchers at Washington University School of Medicine in St. Louis.

21 Nov 2021

Study identifies possible link between psychological stress and Crohn's disease flare-ups

A possible link between psychological stress and Crohn's disease flare-ups has been identified by a McMaster University-led study.

18 Nov 2021

Research shows how inflammatory reactions can be resolved by changes to metabolism of macrophages

New data from a research team at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) shows how inflammatory reactions can be resolved by changes to the metabolism of macrophages.

7 Nov 2021

Study identifies serotonin as a possible trigger of flare-ups in Crohn's disease

A new treatment may be on the horizon for people with a major form of inflammatory bowel disease (IBD) called Crohn's disease, after a McMaster University-led study identified serotonin as a possible trigger of flare-ups.

6 Nov 2021

IBD patients produce a strong antibody response to COVID-19 vaccination, finds study

Researchers at Cedars-Sinai found that patients with inflammatory bowel disease (IBD)─whose treatment can weaken the immune system─produced a strong antibody response to COVID-19 vaccination.

2 Nov 2021

Novel drug improves management of ulcerative colitis

A new drug improved management of ulcerative colitis, according to a study published in the New England Journal of Medicine.

2 Nov 2021

Can targeting autophagy become a new approach to COVID-19 treatment?

In a recent review, the author discusses autophagy as a contributing mechanism of selected drugs that are currently being evaluated to treat COVID‐19.

25 Oct 2021

Biosimilar drugs are cheaper than biologics. Are they similar enough to switch?

It took years for Elle Moxley to get a diagnosis that explained her crippling gastrointestinal pain, digestion problems, fatigue, and hot, red rashes.

23 Sep 2021

Researchers uncover a molecular mechanism to inhibit aggravation of colitis

The intestinal microbial ecosystem includes diverse species of bacteria. These bacteria can produce bioactive metabolites that directly affect the host's immune system.

21 Sep 2021

Humoral and cellular response to COVID-19 vaccines in patients with IBD

A new study published in the preprint server medRxiv* aimed to evaluate the humoral and cellular response to COVID-19 vaccine in patients with IBD undergoing biologic or immunomodulatory therapy.

17 Sep 2021

Unique imaging technique sheds light on how cells related to IBD affect intestinal tissues

New "maps" of hundreds of thousands of cells related to inflammatory bowel disease shed greater light on their effects on intestinal tissues through a newly utilized imaging technique called "imaging mass cytometry."

16 Sep 2021

UTSW researchers discover how vitamin A enters immune cells in the intestines

Immunologists and geneticists at UT Southwestern Medical Center have discovered how vitamin A enters immune cells in the intestines – findings that could offer insight to treat digestive diseases and perhaps help improve the efficacy of some vaccines.

16 Sep 2021

Highly extensive Gut Cell Atlas will transform research into intestinal diseases

Many diseases have their origin in early human development, and today (8th September), two publications in Nature reveal how researchers from the Human Cell Atlas (HCA) consortium are advancing understanding of this.

9 Sep 2021

Georgia State researcher receives award to investigate the influence of environment on IBD

Dr. Michal Kuczma, a research assistant professor in the Institute for Biomedical Sciences at Georgia State University, has received a three-year, $270,000 Career Development Award from the Crohn's and Colitis Foundation to study environmental influences on gut microbiota, immunity and inflammation.

4 Sep 2021

$1.3 million in NIH funding to enable drug delivery technology research

Two National Institute of Health grants totaling over $1.3 million will enable research into antibody-mediated drug delivery technology for the treatment of cancer and autoimmune disorders. L. Nathan Tumey, assistant professor of pharmaceutical sciences at Binghamton University, State University of New York, is the Principal Investigator on both grants -; $1.2 million from the National Institute of General Medical Sciences and $150,000 from the National Institute of Allergy and Infectious Diseases.

31 Aug 2021

Hidradenitis suppurativa: Discontinuation of adalimumab prior to surgery is not necessary

Hidradenitis suppurativa (Syn. Acneinversa) is one of the most troublesome and complicated skin diseases. The anti-inflammatory drug adalimumab can improve symptoms; however, patients also often have to undergo surgery.

19 Aug 2021

Newly identified genetic mutation causes rare, early onset inflammatory bowel disease

Johns Hopkins Medicine researchers, in collaboration with national and international researchers, have identified a genetic mutation in a small number of children with a rare type of inflammatory bowel disease.

30 Jul 2021

Crohn's Disease News and Research

Latest Crohn's Disease News and Research

People with IBD accumulate more fecal microplastics, study finds

A new approach for drugs to be more effective against inflammatory bowel disease

Researchers mapping the extent of IBD in the UK are seeking people's help

People taking immunosuppressant produce weaker, shorter-lived antibodies after COVID-19 vaccination

Study identifies possible link between psychological stress and Crohn's disease flare-ups

Research shows how inflammatory reactions can be resolved by changes to metabolism of macrophages

Study identifies serotonin as a possible trigger of flare-ups in Crohn's disease

IBD patients produce a strong antibody response to COVID-19 vaccination, finds study

Novel drug improves management of ulcerative colitis

Can targeting autophagy become a new approach to COVID-19 treatment?

Biosimilar drugs are cheaper than biologics. Are they similar enough to switch?

Researchers uncover a molecular mechanism to inhibit aggravation of colitis

Humoral and cellular response to COVID-19 vaccines in patients with IBD

Unique imaging technique sheds light on how cells related to IBD affect intestinal tissues

UTSW researchers discover how vitamin A enters immune cells in the intestines

Highly extensive Gut Cell Atlas will transform research into intestinal diseases

Georgia State researcher receives award to investigate the influence of environment on IBD

$1.3 million in NIH funding to enable drug delivery technology research

Hidradenitis suppurativa: Discontinuation of adalimumab prior to surgery is not necessary

Newly identified genetic mutation causes rare, early onset inflammatory bowel disease

Arrayed CRISPR Screening for Revolutionizing Target Discovery

Innovations in baculovirus–insect cell expression systems

Compound Management and its Crucial Role in Early Pharmaceutical Research

Crohn's Disease News and Research

Latest Crohn's Disease News and Research

Arrayed CRISPR Screening for Revolutionizing Target Discovery

Innovations in baculovirus–insect cell expression systems

Compound Management and its Crucial Role in Early Pharmaceutical Research

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