Dendritic Cell News and Research

Latest Dendritic Cell News and Research

Transient cell-in-cell formation by tumor cells found to build resistance to immunotherapy

Researchers demonstrated that tumor cells evade immunotherapy by generating unique transient cell-in-cell structures, resistant to chemotherapy and destruction by T cells.

5 Oct 2022

What are the unique traits of Long COVID?

In a new study, researchers identified distinctive characteristics of post-acute sequelae of COVID-19 (PASC) via immune profiling.

12 Aug 2022

Persistent viral infections within hosts cause post-acute sequelae of COVID-19, research shows

A research team, comprised of Associate Professor Tomonari Sumi of the Research Institute for Interdisciplinary Science at Okayama University and Associate Professor Kouji Harada of the Center for IT-based Education at Toyohashi University of Technology, has developed a mathematical model of the immune response within infected hosts that considers systemic infection of a novel coronavirus (SARS-CoV-2), and demonstrated by conducting experimental computer simulations that persistent viral infections within hosts potentially cause long COVID or post-acute sequelae of COVID-19.

3 Aug 2022

Research could pave the way for therapeutic strategies targeting DCIR to treat colorectal tumors

Colorectal tumors are a common adverse effect of chronic inflammation of the intestine. In a new study, researchers from Japan and China demonstrate that mice models with dendritic cell immunoreceptor (DCIR) protein deficiency are resistant to colonic tumors induced by dextran sodium sulfate and azoxymethane.

2 Aug 2022

Novel mechanism to turn on cancer-killing T cells identified

Over the past decade, researchers have made great strides in the development and administration of cancer immunotherapies, which use the body's own immune system to treat disease.

25 May 2022

An atlas of human immune cells across tissues

In a recent article published in the Science journal, researchers demonstrated tissue-specific immune cell characteristics in humans by performing cross-tissue immune cell evaluation.

16 May 2022

Single-cell RNA sequencing reveals characteristics of myeloid immune cells in coronary plaque

Through single-cell RNA sequencing, a research group has successfully illuminated the characteristics of Myeloid immune cells in coronary plaque, which causes acute coronary syndrome (this term includes conditions such as unstable angina and acute myocardial infarction (heart attack)).

6 May 2022

Nanocell COVID-19 vaccine elicits potent neutralizing response

A new study describes the high level of neutralizing antibodies elicited by a nanocell vaccine against SARS-CoV-2 in vitro, in vivo, and human studies.

11 Apr 2022

Study explores molecular mechanisms underlying SARS-CoV-2 infection of macrophages and the induction of pro-inflammatory cytokines

Researchers examined the role of sialic acid-binding immunoglobulin-type lectins-1, a myeloid cell-specific receptor, in facilitating SARS-CoV-2 infection of ACE2-deficient macrophages and its effect on pro-inflammatory cytokine expression.

1 Apr 2022

Role of SARS-CoV-2 S1 subunit in severe COVID-19

A new study aimed to determine whether portions of the SARS-CoV-2 spike protein are capable of activating innate immune cells like Gal-3.

30 Mar 2022

Mathematical model of host immune response to SARS-CoV-2 demonstrates that age-related risk factors increased viral load

Researchers evaluated the host immune responses to SARS-CoV-2 and its prolonged symptoms.

21 Feb 2022

Similarities and dissimilarities in immune responses and metabolism in SARS-CoV-2 and HIV-1 infections

A new study, posted to the bioRxiv* preprint server, has developed a single-cell atlas that presents the shared and distinct immune responses and metabolism following SARS-CoV-2 and HIV-1 infections.

13 Jan 2022

Role of leptin in immune modulation and pathophysiology of COVID-19

A recent review paper in the journal Frontiers in Physiology discusses the role of leptins in infection with SARS-CoV-2 that triggered the ongoing COVID-19 pandemic.

13 Jan 2022

Nanovaccines and their immunomodulatory effect against human viruses

A review ]presented the primary progress of nanovaccines against the main viral illnesses.

13 Jan 2022

Omicron infection induces cross-reactive immune responses

New research revealed that vaccine-breakthrough infections might elicit cross-reactive bNAbs against all variants of concern.

31 Dec 2021

Impact of a pan-sarbecovirus dendritic-cell targeting vaccine on SARS-CoV-2 variants

A new study used in silico approaches for designing a next-generation CD40-targeting vaccine, CD40.

31 Dec 2021

Protein-based nanoparticle vaccines for protection against SARS-CoV-2

A recent review article discusses recent advances in protein-based nanoparticle vaccines against SARS-CoV-2.

22 Dec 2021

Measuring airway inflammation when diagnosing and treating asthma patients

In this interview, Carol Stonham, the head of a Locality Based FeNO referral service, talks to NewsMed about measuring airway inflammation when diagnosing and treating asthma patients.

From Bedfont® Scientific Ltd 21 Dec 2021

Immune cells play a much larger role in the onset of allergies than previously thought

A ground-breaking discovery from the Malaghan Institute has shone a light on immune cells in the skin, suggesting they play a much larger role in the onset of allergies than first thought.

2 Dec 2021

Immunogenicity of modified microparticle-adjuvanted SARS-CoV-2 vaccine

Researchers investigated the immunogenicity of a novel adjuvant comprised of a modified porous silicon microparticle for the SARS-CoV-2 S protein RBD subunit vaccine.

29 Nov 2021

Dendritic Cell News and Research

Latest Dendritic Cell News and Research

Transient cell-in-cell formation by tumor cells found to build resistance to immunotherapy

What are the unique traits of Long COVID?

Persistent viral infections within hosts cause post-acute sequelae of COVID-19, research shows

Research could pave the way for therapeutic strategies targeting DCIR to treat colorectal tumors

Novel mechanism to turn on cancer-killing T cells identified

An atlas of human immune cells across tissues

Single-cell RNA sequencing reveals characteristics of myeloid immune cells in coronary plaque

Nanocell COVID-19 vaccine elicits potent neutralizing response

Study explores molecular mechanisms underlying SARS-CoV-2 infection of macrophages and the induction of pro-inflammatory cytokines

Role of SARS-CoV-2 S1 subunit in severe COVID-19

Mathematical model of host immune response to SARS-CoV-2 demonstrates that age-related risk factors increased viral load

Similarities and dissimilarities in immune responses and metabolism in SARS-CoV-2 and HIV-1 infections

Role of leptin in immune modulation and pathophysiology of COVID-19

Nanovaccines and their immunomodulatory effect against human viruses

Omicron infection induces cross-reactive immune responses

Impact of a pan-sarbecovirus dendritic-cell targeting vaccine on SARS-CoV-2 variants

Protein-based nanoparticle vaccines for protection against SARS-CoV-2

Measuring airway inflammation when diagnosing and treating asthma patients

Immune cells play a much larger role in the onset of allergies than previously thought

Immunogenicity of modified microparticle-adjuvanted SARS-CoV-2 vaccine

Immunology eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

Dendritic Cell News and Research

Latest Dendritic Cell News and Research

Immunology eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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