Estrogen News and Research

Latest Estrogen News and Research

Examining the effect of hormone replacement therapy on postmenopausal heart disease and cognitive decline

Many are aware of the short-term symptoms often associated with menopause, such as hot flashes, which are attributed to changes in reproductive hormones.

9 Mar 2023

Cedars-Sinai study reveals new insights into the effects of hormonal treatment for transgender men

New insights into the effects of a hormonal treatment for transgender men, discovered by Cedars-Sinai investigators, could have implications for the treatment of breast cancer.

8 Mar 2023

Study paves the way to new sex-specific anti-obesity drugs

Sex differences exist in the regulation of energy homeostasis, the organism's mechanism to keep a stable body weight. Current studies indicate for instance that female mammals, including humans, are better protected against metabolic diseases during reproductive age.

7 Mar 2023

Aggression neurons activate while watching fights

A recent study discusses the processes and changes in the brain that arise while fighting and watching intense fights.

6 Mar 2023

Tumors' response to hormone therapy may be a biomarker for personalization of breast radiotherapy

How estrogen receptor-positive (ER+) breast cancer responds to hormone therapy may hold keys to understanding how it will respond to radiation therapy, and an experimental drug that increases the effectiveness of hormone therapy also overcomes radiation resistance in breast cancer, a study by UT Southwestern Medical Center researchers shows.

6 Mar 2023

Women’s heart disease pioneer receives the 2023 Master of the ACC Award

Noel Bairey Merz, MD, professor of cardiology and the director of the Barbra Streisand Women's Heart Center in the Smidt Heart Institute, will receive the 2023 Master of the ACC Award from the American College of Cardiology in honor of her pioneering contributions to the cardiovascular profession.

3 Mar 2023

Multi-organ scRNA-seq reveals targeting pro- or anti-inflammatory regulators may be exploited for personalized treatment of immune diseases

Researchers performed multi-organ single-cell RNA sequencing of collagen-induced arthritis murine model to evaluate immune-mediated inflammatory disease alterations by characterizing the genome, organizing the organome, and prioritizing pathways in the multi-organ data.

3 Mar 2023

Study reveals synergistic impact of estrogen and intestinal dysbiosis on pulmonary fibrosis

In a recent study published in Cells, researchers evaluated idiopathic pulmonary fibrosis (IPF) pathophysiological differences by sex and intestinal microbiome.

1 Mar 2023

What is the role of B cells in breast cancer pathology?

In a recent study published in Cancers, researchers comprehensively summarized all available information about B cells in the context of breast cancer.

1 Mar 2023

Hormone replacement therapy for gender dysphoria may increase risk of serious cardiac events

People with gender dysphoria taking hormone replacements as part of gender affirmation therapy face a substantially increased risk of serious cardiac events, including stroke, heart attack and pulmonary embolism, according to a study presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

23 Feb 2023

Effects of nanoparticles on gouty arthritis in animal models of gout

Researchers performed a systematic review and meta-analysis to explore the effects of nanoparticles on gouty arthritis using animal models.

23 Feb 2023

Men who regularly lift heavy objects at work have higher sperm counts, study suggests

A new study from researchers from Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, suggests that men who regularly lift heavy objects at work have higher sperm counts.

22 Feb 2023

Income level impacts tumor recurrence and survival in women with ER-positive breast cancer

Patients with early-stage estrogen receptor-positive breast cancer who live in low-income neighborhoods are likelier to have more-aggressive tumors and significantly lower overall survival (OS) than those in higher-income neighborhoods, according to research led by Roswell Park Comprehensive Cancer Center.

21 Feb 2023

FDA approves first drug for ESR1-mutated breast cancer

Dr. Rajkumar Lakshmanaswamy, Ph.D., Chair of the Department of Molecular and Translational Medicine, Center of Emphasis in Cancer and Dean of the L. Frederick Francis Graduate School of Biomedical Sciences at Texas Tech University Health Sciences Center El Paso is available to speak on the Federal Drug Administration's approval of the selective estrogen receptor (ER) degrader elacestrant (Orserdu).

9 Feb 2023

UT Southwestern research could lead to new ways of controlling gene regulation

UT Southwestern Medical Center researchers have discovered a method cells use to turn genes on and off that involves portions of proteins whose function has long been a mystery.

3 Feb 2023

Deletion of a tumor suppressor gene promotes luminal breast cancer development and resistance to endocrine therapy

A research team from LKS Faculty of Medicine, the University of Hong Kong (HKUMed) discovered that somatic deletion of a tumor suppressor gene AKTIP promotes luminal breast cancer development and resistance to endocrine therapy.

3 Feb 2023

Mays Cancer Center leads a study evaluating Phase I and Phase III clinical trials for breast cancer drug

The Mays Cancer Center, home to UT Health San Antonio MD Anderson Cancer Center, was the lead site for a study evaluating Phase I and Phase III clinical trials for elacestrant, a treatment for postmenopausal women and adult men with ER+/HER2- advanced or metastatic breast cancer.

1 Feb 2023

Adding veliparib to chemotherapy can extend progression-free survival in patients with “BRCA-like” breast cancer

Results from the SWOG S1416 clinical trial show that adding veliparib to chemotherapy can significantly extend progression-free survival (PFS) times in patients with triple-negative breast cancer (TNBC) that has a "BRCA-like" phenotype.

31 Jan 2023

UK oncologists and cardiologists collaborate to prevent chemo-induced cardiomyopathy in cancer patients

Ever since she was 12 years old, Barbie Johnson has been a Kentucky girl at heart. Raised in the bluegrass, Barbie has worked at UK HealthCare for 18 years, first in gynecologic oncology and now in surgery scheduling.

26 Jan 2023

New therapy-relevant marker may help identify ER+ breast cancer patients who may benefit from immunotherapies

A multi-institutional team led by scientists from the Medical College of Wisconsin Cancer Center has discovered PD-L2 as a therapy-relevant marker to identify patients with estrogen receptor-positive breast cancer who may benefit from new immunotherapies.

26 Jan 2023

Estrogen News and Research

Latest Estrogen News and Research

Examining the effect of hormone replacement therapy on postmenopausal heart disease and cognitive decline

Cedars-Sinai study reveals new insights into the effects of hormonal treatment for transgender men

Study paves the way to new sex-specific anti-obesity drugs

Aggression neurons activate while watching fights

Tumors' response to hormone therapy may be a biomarker for personalization of breast radiotherapy

Women’s heart disease pioneer receives the 2023 Master of the ACC Award

Multi-organ scRNA-seq reveals targeting pro- or anti-inflammatory regulators may be exploited for personalized treatment of immune diseases

Study reveals synergistic impact of estrogen and intestinal dysbiosis on pulmonary fibrosis

What is the role of B cells in breast cancer pathology?

Hormone replacement therapy for gender dysphoria may increase risk of serious cardiac events

Effects of nanoparticles on gouty arthritis in animal models of gout

Men who regularly lift heavy objects at work have higher sperm counts, study suggests

Income level impacts tumor recurrence and survival in women with ER-positive breast cancer

FDA approves first drug for ESR1-mutated breast cancer

UT Southwestern research could lead to new ways of controlling gene regulation

Deletion of a tumor suppressor gene promotes luminal breast cancer development and resistance to endocrine therapy

Mays Cancer Center leads a study evaluating Phase I and Phase III clinical trials for breast cancer drug

Adding veliparib to chemotherapy can extend progression-free survival in patients with “BRCA-like” breast cancer

UK oncologists and cardiologists collaborate to prevent chemo-induced cardiomyopathy in cancer patients

New therapy-relevant marker may help identify ER+ breast cancer patients who may benefit from immunotherapies

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Estrogen News and Research

Latest Estrogen News and Research

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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