Inflammatory Bowel Disease News and Research

Latest Inflammatory Bowel Disease News and Research

Research links intestinal inflammation with systemic chromosome damage

UCLA scientists have linked for the first time intestinal inflammation with systemic chromosome damage in mice, a finding that may lead to the early identification and treatment of human inflammatory disorders, some of which increase risk for several types of cancer.

1 Jun 2009

Stem cell focus for inflammatory bowel disease wound healing

Scientists at The University of Nottingham are investigating whether stem cell markers could have a role to play in speeding up wound healing in patients suffering from inflammatory bowel disease (IBD).

30 Apr 2009

MR enterography eliminates unnecessary radiation exposure in patients with small bowel disease

MR enterography is an effective tool to evaluate and guide treatment of patients with Crohn's Disease (a common form of inflammatory bowel disease that typically affects young people) without exposing them to radiation, according to a study performed at the Warren Alpert School of Medicine/Brown University in Providence, RI.

23 Apr 2009

Colon cancer shuts down receptor that could shut it down

Though a high-fiber diet has long been considered good for you and beneficial in staving off colon cancer, Medical College of Georgia researchers have discovered a reason why: roughage activates a receptor with cancer-killing potential.

13 Apr 2009

Research sheds new light on inflammatory disease

Scientists at the University of Liverpool have found that understanding the precise timing of communication between cells that coordinate the body's response to disease could be key to new drug developments.

12 Apr 2009

Scientists discover the secrets of NF-kappaB

A study published in Science examines a key player in conditions such as cancer, inflammatory bowel disease, rheumatoid arthritis and asthma and has shown that cells use a sophisticated communication system to coordinate responses to infection and maintain inflammation in the body.

12 Apr 2009

Colonoscopy versus virtual colonoscopy

Today, patients have a wide selection of colorectal cancer screening exams from which to choose, unlike with other types of cancers.

2 Apr 2009

Colon cancer screenings recommended at 45 for African Americans

According to the American Cancer Society, there were about 108,070 new cases of colon cancer and 40,740 new cases of rectal cancer in 2008. Overall, the two cancers caused nearly 50,000 deaths last year.

16 Mar 2009

Small molecules block cancer gene

Finding molecules that block the activity of the oncogene Stat 3 (signal transducer and activator of transcription) required screening literally millions of compounds, using computers that compared the structure of the cancer-causing gene to those of the small molecules, said a Baylor College of Medicine researcher in a report that appears in the current online issue of the journal PLoS One (Public Library of Science ONE).

11 Mar 2009

Colonoscopy and virtual colonoscopy, either way get screened!

Today, patients have a wide selection of colorectal cancer screening exams from which to choose, unlike with other types of cancers.

3 Mar 2009

Novel approach to gene hunting uncovers possible new targets for Crohn's disease drugs

Discovering the different genes that contribute to a complex disease is like searching in the proverbial haystack for an unknown number of needles--some much smaller than others, often blending into the background, and many of them widely separated from each other.

26 Feb 2009

Investing in personalized medicine will benefit Canada

Canada has the opportunity to be an international leader in personalized medicine and needs to invest in this area for the health of Canadians and to reap the benefits of job creation, writes Dr. Thomas Hudson in a commentary http://www.cmaj.ca/cgi/rapidpdf/cmaj.1090199 released online today in CMAJ ( Canadian Medical Association Journal ).

20 Feb 2009

New understanding on how inflammatory disease causes fatigue

New animal research in the February 18 issue of The Journal of Neuroscience may indicate how certain diseases make people feel so tired and listless.

18 Feb 2009

Researchers identify mutation that causes inflammatory bowel disease

A team of scientists at The Scripps Research Institute has linked a mouse mutation to an increased susceptibility for developing inflammatory bowel disease -- represented in humans as Crohn's disease and ulcerative colitis, which together are estimated to affect more than a million people in the United States.

10 Feb 2009

New potential targets for colitis-associated cancer

Recent research from the laboratory of Michael Karin, PhD, at the University of California, San Diego School of Medicine - the first researcher to demonstrate a molecular link between inflammation and cancer - has identified two potential targets for the prevention and treatment of colitis-associated cancer (CAC), the most serious complication of inflammatory bowel disease.

2 Feb 2009

Unexpected finding opens up new way to stop autoimmune diseases and transplant rejection

After several years of battling recurring infections, the last thing a patient and her doctors ever expected was that the cause of her problems might actually help millions live longer, more active lives.

23 Jan 2009

Epigenetics may account for some inherited traits and diseases

Embargoed Until January 18, 2009 at 18:00 Greenwich Mean Time / 13:00 Eastern Standard Time (TORONTO): Scientists at the Centre for Addiction and Mental Health (CAMH) have detected evidence that DNA may not be the only carrier of heritable information; a secondary molecular mechanism called epigenetics may also account for some inherited traits and diseases.

19 Jan 2009

New genetic markers for ulcerative colitis could lead to treatment

An international consortium of researchers, including major contribution from a team led by Dr. John D. Rioux, a professor of medicine at the Université de Montréal and the Montreal Heart Institute, has identified genetic markers associated with risk for ulcerative colitis.

8 Jan 2009

Discovery of more efficient way to create induced Pluripotent Stem (iPS) cells

A Boston University School of Medicine-led research team has discovered a more efficient way to create induced Pluripotent Stem (iPS) cells, derived from mouse fibroblasts, by using a single virus vector instead of multiple viruses in the reprogramming process.

7 Jan 2009

Discovery of new genetic markers for ulcerative colitis

An international team led by University of Pittsburgh School of Medicine researchers has identified genetic markers associated with risk for ulcerative colitis.

5 Jan 2009