Metabolism News and Research

Latest Metabolism News and Research

UT Health San Antonio achieves top global ranking for research and clinical medicine

The race to draw the best and brightest students has become an international one, with candidates weighing options not only in their state or country, but also across the globe.

15 Nov 2024

CAR T cell therapy breakthroughs bring new hope for treating solid tumors

Researchers advance CAR T cell therapy for solid tumors by innovating ways to overcome the unique barriers of solid tumor environments, with promising clinical results.

13 Nov 2024

New study links circadian gene variants to winter depression

Variants of the PER3 gene disrupt adrenal adaptation to winter light, leading to serotonin disruption and depression-like behaviors in humanized mice models.

13 Nov 2024

The synergy of nutrition and traditional medicine for holistic health and wellbeing

Researchers explore how nutrition and traditional medicine can support holistic health.

13 Nov 2024

Vitamin D receptor activation slows cell overgrowth in pulmonary hypertension

The study demonstrates that activating the vitamin D receptor (VDR) with calcitriol suppresses cell proliferation in pulmonary arterial smooth muscle cells, potentially reducing disease severity in pulmonary arterial hypertension (PAH).

12 Nov 2024

Western diet accelerates endometriosis growth and disrupts gut health

This study found that a Western diet doubles the growth of endometriotic lesions in mice and depletes the gut microbiome's beneficial bacterium, Akkermansia muciniphila, which may exacerbate endometriosis symptoms.

12 Nov 2024

Novel compound BHB-Phe could offer new approach to weight loss

Researchers at Baylor College of Medicine, Stanford University School of Medicine and collaborating institutions report in the journal Cell the discovery of BHB-Phe, a novel compound produced by the body that regulates appetite and body weight through interactions with neurons in the brain.

12 Nov 2024

Mitochondria’s division of labor sheds light on how cancer cells survive harsh conditions

Research shows mitochondria form distinct subpopulations under nutrient stress, revealing survival mechanisms in cancer cells and potential therapeutic targets.

12 Nov 2024

Cannabinol enhances sleep in rats, study shows

Research by scientists at the University of Sydney has identified a constituent in the cannabis plant that improves sleep.

11 Nov 2024

Gut microbiome changes linked to onset of rheumatoid arthritis among at-risk individuals

Findings indicate gut microbiome diversity changes precede rheumatoid arthritis, offering insights into microbial indicators for early disease detection.

11 Nov 2024

Studies link gut dysbiosis to pancreatic cancer, offering pathways for early detection

The gut microbiome's impact on pancreatic cancer highlights potential for early screening and fecal microbiota transplantation in improving treatment efficacy.

11 Nov 2024

Heat exposure significantly heightens risks for maternal and newborn health

The study reveals that heat exposure increases health risks for pregnant women and their babies, impacting outcomes like preterm birth, low birth weight, and hypertensive disorders.

10 Nov 2024

How gut bacteria regulate stress and sleep cycles

This study reveals that gut microbiota, particularly Lactobacillus species, regulate the daily rhythm of stress hormones like corticosterone, influencing stress responses and brain function at different times of the day. Disruptions in gut bacteria lead to altered stress responses and increased susceptibility to disorders like depression.

10 Nov 2024

New approach reinvigorates exhausted T cells to improve tumor control

As cancer cells grow, they pump out metabolic byproducts such as lactic acid into the tumor microenvironment. Exhausted T cells - which have lost their cancer-fighting oomph - consume this lactic acid, which further saps their energy, according to new research from the University of Pittsburgh and UPMC Hillman Cancer Center.

8 Nov 2024

Exploring the protective effects of HSD17B13 in hepatic steatosis

Chronic liver disease (CLD) is a growing global health challenge, accounting for millions of deaths each year. Its major contributors include metabolic dysfunction-associated steatohepatitis (MASH), alcoholic liver disease (ALD), and hepatitis C virus infection.

8 Nov 2024