Metabolism News and Research

Latest Metabolism News and Research

Unveiling the metabolic pathways of Fusobacterium nucleatum in OSCC

A recent study has made significant strides in uncovering how the oral microbiome, particularly the bacterium Fusobacterium nucleatum, plays a crucial role in the progression of oral squamous cell carcinoma (OSCC). By identifying key interactions between this common oral bacterium and host cells, the research has unveiled important metabolic pathways and mechanisms that may serve as potential therapeutic targets.

17 Jan 2025

Immune cells orchestrate glucagon production during fasting

When we think about the immune system, we usually associate it with fighting infections. However, a study published in Science by the Champalimaud Foundation reveals a surprising new role.

17 Jan 2025

AstraZeneca's Pioneering Research in Heart Failure and ATTR-CM

Mina Makar highlights AstraZeneca's commitment to advancing heart failure research and innovative therapies, addressing critical needs in cardiovascular health.

16 Jan 2025

Could mulberry extract be the key to fighting obesity-induced reproductive dysfunction?

Research indicates mulberry extract's efficacy in addressing obesity-related male infertility, enhancing reproductive outcomes through bioactive compounds.

16 Jan 2025

Unlocking the neural basis of overeating

Can memory influence what and how much we eat? A groundbreaking Monell Chemical Senses Center study, which links food memory to overeating, answered that question with a resounding "Yes." Led by Monell Associate Member Guillaume de Lartigue, PhD, the research team identified, for the first time, the brain's food-specific memory system and its direct role in overeating and diet-induced obesity.

16 Jan 2025

Antihistamine shows promise for treating rare genetic liver disease

A common antihistamine may offer hope for patients with a rare genetic disease that can lead to severe liver damage and ultimately require transplantation, according to new research from Rutgers Health.

16 Jan 2025

Exercise offers hope in the Alzheimer's battle

Regular aerobic exercise could significantly reduce disease markers associated with Alzheimer's, new research led by scientists at the University of Bristol (UK) and the Federal University of São Paulo (Brazil) has found. The findings provide new hope in the battle against this devastating disorder.

16 Jan 2025

Hormonal shifts in menopause redefine women’s microbiome and risks

Research explores how menopause-induced hormonal shifts affect the microbiome, influencing oral, gut, and urogenital health, and highlights the potential of personalized interventions to enhance well-being.

15 Jan 2025

Study identifies molecular mechanisms behind gestational diabetes progression

Among those who have had gestational diabetes, about 35% will develop type 2 diabetes within a decade.

15 Jan 2025

Study unravels the links between obesity and cancer

Obesity, recognized as a complex and growing health issue, is associated with an increased risk of various cancers. A comprehensive review provides insights into the mechanisms linking obesity to cancer risk and discusses potential clinical implications.

15 Jan 2025

A new strategy for enhancing the production of protein-based drugs

An international team of researchers led by the University of California San Diego has developed a new strategy to enhance pharmaceutical production in Chinese hamster ovary (CHO) cells, which are commonly used to manufacture protein-based drugs for treating cancer, autoimmune diseases and much more.

15 Jan 2025

Proteomic mapping identifies biomarkers driving healthy aging and preventing chronic diseases

Scientists mapped the serum proteome longitudinally to uncover biomarkers linked to healthy aging and cardiometabolic diseases, revealing potential therapeutic targets.

14 Jan 2025

High-fat diet linked to impulsive behaviors and brain changes

Researchers examines how a high-fat diet modifies inhibitory control.

14 Jan 2025

Gut microbiome dynamics reveal key factors influencing Enterobacteriaceae colonization

Analysis of gut microbiomes reveals co-colonization patterns and potential therapeutic targets against Enterobacteriaceae, addressing global health challenges.

14 Jan 2025

Morning coffee cuts health risks, but all-day sipping doesn’t

Moderate morning coffee consumption may lower all-cause and cardiovascular mortality risks, but coffee consumed throughout the day offers no similar benefits.

13 Jan 2025

Scientists uncover genetic secrets of Staphylococcus aureus survival in humans

The most detailed study to date on the mechanisms by which a common type of bacterium, Staphylococcus aureus, adapts to living on the human body could help improve the prevention, diagnosis, and treatment of certain infections.

13 Jan 2025

Discovery of key protein for burning fat may lead to obesity treatments

Obesity, which affects 650 million people worldwide, influences the development of cardiometabolic diseases and increases the risk of cancer.

13 Jan 2025

Gut bacterium associated with reduced dietary sugar intake

This study links Ffar4, gut microbiota, and sugar preference, highlighting potential strategies for managing diabetes and obesity through dietary interventions.

13 Jan 2025

Short-chain fatty acids propionate and butyrate directly modify chromatin to regulate gene expression

Short-chain fatty acids influence gene regulation and chromatin accessibility, highlighting their role in colorectal cancer and normal cellular processes.

13 Jan 2025

New guidelines for correct use of biochemical indices of bone statuss published

The Joint International Osteoporosis Foundation (IOF) Working Group and the International Federation of Clinical Chemistry (IFCC) Committee on Bone Metabolism have published important updated guidelines for the correct use of biochemical indices of bone status.

10 Jan 2025