Metabolism News and Research

Latest Metabolism News and Research

Gut bacteria and diet found to affect cancer treatment outcomes

A Ludwig Cancer Research study has uncovered a surprising link between diet, intestinal microbes and the efficacy of cancer therapy.

22 May 2025

Cysteine depletion triggers rapid weight loss in mice

Mice genetically engineered to lack the ability to make the amino acid cysteine, and fed a cysteine-free diet, lost 30 percent of their body weight in just one week, a new study shows.

22 May 2025

Blood and urine tests reveal how much ultra-processed food you really eat, study finds

Researchers developed and validated blood and urine metabolite scores that objectively measure ultra-processed food (UPF) intake in adults. These biomarker profiles accurately distinguished between high- and low-UPF diets and may transform nutrition research and public health monitoring.

21 May 2025

Vitamin D supplements help preserve telomere length in aging adults

Results from the VITAL randomized controlled trial reveal that vitamin D supplementation helps maintain telomeres, protective caps at the ends of chromosomes that shorten during aging and are linked to the development of certain diseases.

21 May 2025

Microplastics in ultra-processed foods may fuel mental health risks, experts warn

New research highlights a possible link between microplastics in ultra-processed foods and rising rates of depression, anxiety, and sleep problems. Experts call for urgent investigation as microplastic accumulation in the human brain increases alongside ultra-processed food intake.

21 May 2025

Exploring the link between microbial balance and aging mechanisms

Aging is a multifaceted process driven by interconnected biological mechanisms, among which genomic instability and telomere attrition stand as primary hallmarks.

20 May 2025

Gut bacteria and genes jointly shape obesity risk, review reveals hidden links

Researchers examined the heritability of body mass index (BMI), highlighting that genetics and the gut microbiome both play major roles in obesity risk. The review emphasizes that maternal microbiome transmission and family environment may help explain “missing heritability” beyond known genetic factors.

20 May 2025

Cell Painting technology uncovers flavonoids with potential to treat bladder cancer

A team led by researchers at Baylor College of Medicine has identified flavonoids, natural compounds found in plants, that are toxic to bladder cancer cells cultured in the lab.

20 May 2025

NIH researchers develop poly-metabolite score to measure ultra-processed food intake

For the first time, researchers at the National Institutes of Health (NIH) identified patterns of metabolites in blood and urine that can be used as an objective measure of an individual's consumption of energy from ultra-processed foods.

20 May 2025

Personalized gene editing corrects fatal infant metabolic disorder in world-first treatment

Researchers have used a personalised base-editing gene therapy to successfully treat an infant with carbamoyl-phosphate synthetase 1 (CPS1) deficiency, a rare and life-threatening inborn error of metabolism. This pioneering approach chemically corrects the underlying mutation without cutting DNA, showing promise for precision treatment of ultrarare genetic disorders.

20 May 2025

Nanozymes offer promise for treating inflammation during pregnancy

Special care must be taken with illnesses during pregnancy, as not all drugs are compatible for mother and child.

20 May 2025

Age-related immune decline reduces CAR-T cell therapy efficacy

As people age, their immune systems become less efficient, posing a challenge for cancer therapies that rely on harnessing immune cells.

20 May 2025

Combination of two drugs shows promise in treating B-cell acute lymphoblastic leukemia

A combination of two drugs could improve outcomes and reduce the need for toxic chemotherapy for B-cell acute lymphoblastic leukemia (B-ALL), the commonest cancer in childhood and one that can be particularly difficult to treat in older patients, according to Cambridge scientists.

20 May 2025

Diabetes drug shows potential in slowing prostate cancer progression

A drug used to treat type 2 diabetes may also be effective in slowing the progression of prostate cancer.

20 May 2025

NELL2 identified as a key regulator of bone formation and fat suppression

A recent study identifies Neural EGFL-like 2 (NELL2), a secreted protein, as a key regulator of bone homeostasis, offering potential therapeutic applications for osteoporosis.

19 May 2025

Sucralose disrupts male fertility by damaging sperm and altering hormones in animal study

Researchers found that chronic sucralose exposure in male rats disrupted reproductive hormones, damaged sperm, and impaired testicular function through oxidative stress and autophagy dysregulation. These findings raise concerns about the reproductive risks of high sucralose intake and its persistent presence in the environment.

19 May 2025

Metabolism News and Research

Latest Metabolism News and Research

Gut bacteria and diet found to affect cancer treatment outcomes

Cysteine depletion triggers rapid weight loss in mice

Blood and urine tests reveal how much ultra-processed food you really eat, study finds

Vitamin D supplements help preserve telomere length in aging adults

Microplastics in ultra-processed foods may fuel mental health risks, experts warn

Exploring the link between microbial balance and aging mechanisms

Gut bacteria and genes jointly shape obesity risk, review reveals hidden links

Cell Painting technology uncovers flavonoids with potential to treat bladder cancer

NIH researchers develop poly-metabolite score to measure ultra-processed food intake

Personalized gene editing corrects fatal infant metabolic disorder in world-first treatment

Nanozymes offer promise for treating inflammation during pregnancy

Age-related immune decline reduces CAR-T cell therapy efficacy

Combination of two drugs shows promise in treating B-cell acute lymphoblastic leukemia

Diabetes drug shows potential in slowing prostate cancer progression

NELL2 identified as a key regulator of bone formation and fat suppression

Sucralose disrupts male fertility by damaging sperm and altering hormones in animal study

Mayo Clinic discovery may help preserve donor hearts longer

Acetate and gut bacteria work together to reduce obesity in mice

Zebrafish study reveals hidden dangers of environmental toxins from tires

Single gene found to play a big role in how the liver stores energy

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh