Morphine

Morphine is an extremely potent opiate analgesic psychoactive drug and is considered to be the prototypical opioid. In clinical medicine, morphine is regarded as the gold standard, or benchmark, of analgesics used to relieve severe or agonizing pain and suffering.

What is Morphine?

Morphine is the most abundant analgesic opiate found in opium and is a potent pain reliever. The drug is used in clinical pain relief but is also used illicitly for recreational purposes among drug users. It is potentially highly addictive and can cause intense physical dependence that leads to abuse of the substance.

Morphine History

Morphine Side Effects

Morphine Pharmacology

Morphine Pharmacokinetics

Morphine Chemistry

Morphine Brands

Morphine Uses

Latest Morphine News and Research

Collaborative grant program boosts health research across Tennessee

Researchers from the University of Tennessee Health Science Center College of Medicine-Knoxville; the University of Tennessee, Knoxville; and the University of Tennessee Health Science Center Office of Research understand the challenges affecting the health and wellness of Tennesseans.

19 Jul 2024

Study identifies a new way to make opioids safer

Researchers at the University of Arizona Health Sciences identified a new way to make opioids safer, increasing the pain-relieving properties of opioids while decreasing unwanted side effects through the spinal inhibition of a Heat shock protein 90 isoform.

17 Jul 2024

Marine fungus-derived aniquinazolin B could be a potential opioid alternative

Opioids have long been known as natural substances with substantial pharmacological effect. They have been used as effective painkillers.

17 Jul 2024

Breakthrough biosensors illuminate opioid dynamics in the brain

New research from a Max Planck Florida Institute for Neuroscience researcher could transform how we understand the way opioids affect the brain.

15 Jul 2024

New research aims to help lessen the risk of opioid misuse and overdose

New research aims to help reduce the quantity of unused prescription opioids after emergency department visits and lessen the risk of opioid misuse and overdose.

15 Jul 2024

UCLA study finds insomnia drug suvorexant prevents opioid addiction in mice

New research led by UCLA Health has found a drug that treats insomnia works to prevent the addictive effects of the morphine opioids in mice while still providing effective pain relief.

9 Jul 2024

Novel compound amplifies naloxone's power to reverse overdoses

In a Stanford Medicine-led study, researchers combed through billions of compounds to find one that could enhance naloxone’s ability to fend off more potent opioids, with promising results in mice.

4 Jul 2024

Researchers identify potential drugs that make naloxone more potent and longer lasting

The ongoing opioid epidemic in the U.S. kills tens of thousands of people every year. Naloxone, sold under the brand name Narcan, has saved countless lives by reversing opioid overdoses.

3 Jul 2024

Pain doesn’t belong on a scale of zero to 10

Over the past two years, a simple but baffling request has preceded most of my encounters with medical professionals: "Rate your pain on a scale of zero to 10."

2 Jul 2024

Stanford study reveals link between adaptive myelination and drug addiction

Our brains, even in adulthood, continually adapt to what we do, strengthening or weakening neural pathways as we practice new skills or abandon old habits.

5 Jun 2024

Study reveals shared brain mechanism of cocaine and morphine addiction

Mount Sinai researchers, in collaboration with scientists at The Rockefeller University, have uncovered a mechanism in the brain that allows cocaine and morphine to take over natural reward processing systems.

18 Apr 2024

Tiam1 inhibition mitigates morphine tolerance and hyperalgesia in mouse model

Morphine and other opioids are vital to treat severe and chronic pain. However, they have two problems -; prolonged use creates morphine tolerance, where ever-increasing doses are needed for the same pain relief, and paradoxically, prolonged use also can create an extreme sensitivity to pain, called hyperalgesia.

9 Apr 2024

Eating fatty food before surgery may affect memory-related cognitive function in older adults

Eating fatty food in the days leading up to surgery may prompt a heightened inflammatory response in the brain that interferes for weeks with memory-related cognitive function in older adults – and, new research in animals suggests, even in young adults.

15 Mar 2024

West Virginia city once battered by opioid overdoses confronts ‘fourth wave’

From 2006 through 2014, more than 81 million painkiller pills were shipped to this city and surrounding rural Cabell County.

13 Mar 2024

DNA aptamer-based sensors can accurately detect trace amounts of fentanyl, heroin, and cocaine

Researchers from North Carolina State University have developed a new generation of high-performance DNA aptamers and highly accurate drug sensors for cocaine and other opioids.

5 Mar 2024

Records show Publix opioid sales grew even as addiction crisis prompted other chains’ pullback

An executive at Teva Pharmaceuticals flagged Publix Super Markets in October 2015 after detecting what he called in an email "serious red flags" with the grocery chain's orders of powerful opioids.

29 Jan 2024

Morphine shows potential as effective cough therapy for pulmonary fibrosis, study finds

The efficacy of the controlled release of low-dose morphine as treatment against that of a placebo in idiopathic pulmonary fibrosis.

18 Jan 2024

New study challenges "gold standard" opioid treatment for cancer pain

Researchers examining the data on opioids for pain caused by cancer have found surprisingly large gaps in evidence regarding the true benefits of these medicines for cancer pain.

18 Dec 2023

New study casts doubt on effectiveness of opioids for cancer pain

The world's largest review on opioid medicines for cancer pain has found it is unclear whether some commonly used opioid medicines are better than a placebo and suggests that non-opioid medicines, including aspirin, may be as effective as opioids.

18 Dec 2023

Promising candidate medication for preventing and reversing fentanyl-induced overdose

Researchers assessed CSX-1004, a monoclonal antibody (mAb), for its efficacy in reversing fentanyl overdose based on its high affinity for fentanyl, positive animal model results, and safe pharmacokinetic profile, positioning it as a potential solution in the opioid crisis.

7 Dec 2023