Neurofibromatosis News and Research

Latest Neurofibromatosis News and Research

Epilepsy: A true window on the brain

Rapidly emerging technologies, novel imaging techniques, the development of new therapies and new genes, have given researchers and clinicians an extraordinary ability to explore the brain at the cellular, genetic and neural levels. While current epilepsy research may seem like it's ripped from the pages of a science fiction novel, it's real—and even pretty cool.

6 Nov 2014

Researchers explore gene expression in normal vestibular nerves, vestibular schwannomas

Researchers from the University of Toronto, directed by Drs. Gelareh Zadeh and Boris Krischek, investigated gene expression in normal vestibular nerves and vestibular schwannomas (VSs).

24 Sep 2014

Researchers find learning and memory components of neurofibromatosis using zebrafish model

Using a zebrafish model of a human genetic disease called neurofibromatosis (NF1), a team from the Perelman School of Medicine at the University of Pennsylvania has found that the learning and memory components of the disorder are distinct features that will likely need different treatment approaches.

15 Sep 2014

Scientists solve mystery of why specific signaling pathway can be linked with alcohol dependence

Scientists at The Scripps Research Institute (TSRI) have solved the mystery of why a specific signaling pathway can be associated with alcohol dependence.

28 Aug 2014

Enzyme therapy may prevent skeletal abnormalities associated with neurofibromatosis type-1

An enzyme therapy may prevent skeletal abnormalities associated with the genetic disorder neurofibromatosis type-1, Vanderbilt investigators have discovered.

15 Aug 2014

Understanding how some cells in the brain and nervous system turn cancerous

Scientists from the Sloan-Kettering Institute for Cancer Research in New York with the help of Plymouth University Peninsula Schools of Medicine and Dentistry have completed research which for the first time brings us nearer to understanding how some cells in the brain and nervous system become cancerous.

23 Jul 2014

Thomson Reuters, Children's Tumor Foundation partner to create neurofibromatosis pathway maps

The Intellectual Property & Science business of Thomson Reuters, the world's leading provider of intelligent information for businesses and professionals, today announced an expansion of its partnership with the Children's Tumor Foundation to create unique neurofibromatosis (NF) pathway maps aimed at significantly increasing the understanding of the disease and its underlying mechanisms.

4 Apr 2014

Surgeons perform first auditory brainstem implant operation in Northeast Ohio

Surgeons at University Hospitals Case Medical Center have completed the first auditory brainstem implant (ABI) operation in Northeast Ohio on a woman who has lost most of her hearing due to benign tumors on her auditory nerves.

17 Mar 2014

Children with ASD and ADHD are more likely to exhibit gender variance

John F. Strang, PsyD, a pediatric neuropsychologist at Children's National Health System, and colleagues, found that children with autism spectrum disorders (ASD) or attention deficit hyperactivity disorder (ADHD) were more likely to exhibit gender variance, the wish to be the other gender, than children with no neurodevelopmental disorder, or a medical neurodevelopmental disorder such as epilepsy or neurofibromatosis.

13 Mar 2014

Teenagers with autism spectrum disorder are more likely to wish to be another gender

Children and teenagers with an autism spectrum disorder or those who have attention deficit and hyperactivity problems are much more likely to wish to be another gender.

13 Mar 2014

Study establishes innovative approaches to improve vision of young children with brain tumor

Robert Avery, DO, MSCE, of Children's National Health System and colleagues are establishing innovative approaches with technology and medication to improve the vision of young children who have visual pathway glioma, a type of brain tumor.

3 Mar 2014

Researchers examine link between gender and genetic disorder

A genetic disorder that affects about 1 in every 2,500 births can cause a bewildering array of clinical problems, including brain tumors, impaired vision, learning disabilities, behavioral problems, heart defects and bone deformities. The symptoms and their severity vary among patients affected by this condition, known as neurofibromatosis type 1 (NF1).

9 Feb 2014

IDH1 gene mutation determines best treatment for malignant astrocytomas

Astrocytomas are the most common malignant brain tumors. While most patients' tumors prove to be quite aggressive, outcomes overall can vary widely, with some patients surviving for many years.

4 Feb 2014

Study reveals neurons in brain can combine signals of individual elements into behavioural sequence

When you learn how to play the piano, first you have to learn notes, scales and chords and only then will you be able to play a piece of music. The same principle applies to speech and to reading, where instead of scales you have to learn the alphabet and the rules of grammar.

26 Jan 2014

Scientists find inhibiting action of BRD4 protein may eradicate rare type of soft-tissue cancer

A deadly, rare type of soft-tissue cancer may be completely eradicated simply by inhibiting a key protein involved in its growth, UT Southwestern Medical Center researchers report.

27 Dec 2013

Changes to LZTR1 gene predispose people to develop schwannomas

Changes to a gene called LZTR1 predispose people to develop a rare disorder where multiple tumors called schwannomas form near nerve pathways, according to a study published today in the journal Nature Genetics and led by researchers from the University of Alabama at Birmingham.

24 Dec 2013

Standardized research approaches needed for developing new treatments for neurofibromatosis

As potentially effective new treatments for neurofibromatosis (NF) are developed, standardized research approaches—including outcome measures specific to NF—are needed. The first report from the Response Evaluation in Neurofibromatosis and Schwannomatosis (REiNS) International Collaboration has been published as a supplement to Neurology, the Official Journal of the American Academy of Neurology (AAN).

13 Dec 2013

Verastem presents positive results from VS-6063 clinical and preclinical studies at 2013 AACR-NCI-EORTC meeting

Verastem, Inc., focused on discovering and developing drugs to treat cancer by the targeted killing of cancer stem cells, announced positive results from the Phase 1 portion of its Phase 1/1b study of defactinib (VS-6063) in combination with paclitaxel in patients with ovarian cancer that were presented at the 2013 AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics in Boston.

21 Oct 2013

Scientists identify new drug for inherited form of cancer with no known cure

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have identified a new drug candidate for an inherited form of cancer with no known cure.

3 Oct 2013

Stem cell lines are ideal research tools for designing models to understand disease progression

Scientists from King's College London have announced that 16 human embryonic stem (hES) cell lines have been approved by the US National Institutes of Health (NIH) and placed on their Stem Cell Registry, making them freely available for federally-funded research in the USA.

25 Sep 2013

Neurofibromatosis News and Research

Latest Neurofibromatosis News and Research

Epilepsy: A true window on the brain

Researchers explore gene expression in normal vestibular nerves, vestibular schwannomas

Researchers find learning and memory components of neurofibromatosis using zebrafish model

Scientists solve mystery of why specific signaling pathway can be linked with alcohol dependence

Enzyme therapy may prevent skeletal abnormalities associated with neurofibromatosis type-1

Understanding how some cells in the brain and nervous system turn cancerous

Thomson Reuters, Children's Tumor Foundation partner to create neurofibromatosis pathway maps

Surgeons perform first auditory brainstem implant operation in Northeast Ohio

Children with ASD and ADHD are more likely to exhibit gender variance

Teenagers with autism spectrum disorder are more likely to wish to be another gender

Study establishes innovative approaches to improve vision of young children with brain tumor

Researchers examine link between gender and genetic disorder

IDH1 gene mutation determines best treatment for malignant astrocytomas

Study reveals neurons in brain can combine signals of individual elements into behavioural sequence

Scientists find inhibiting action of BRD4 protein may eradicate rare type of soft-tissue cancer

Changes to LZTR1 gene predispose people to develop schwannomas

Standardized research approaches needed for developing new treatments for neurofibromatosis

Verastem presents positive results from VS-6063 clinical and preclinical studies at 2013 AACR-NCI-EORTC meeting

Scientists identify new drug for inherited form of cancer with no known cure

Stem cell lines are ideal research tools for designing models to understand disease progression

Neuroscience - Second Edition eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

Neurofibromatosis News and Research

Latest Neurofibromatosis News and Research

Neuroscience - Second Edition eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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