Pharmacology News and Research

Latest Pharmacology News and Research

Study reveals potential therapeutic target for treating cocaine addiction

A new study explains how cocaine modifies functions in the brain revealing a potential target for therapies aimed at treating cocaine addiction.

22 Apr 2020

Study: Orujo Olive OIL reduces obesity and inflammatory complications in obese mice

Researchers from the Department of Pharmacology, Paediatrics and Radiology at the University of Seville, in collaboration with Dr. Rodriguez from the International University of Catalonia, have confirmed that Orujo Olive OIL (POCTA), when introduced into the diet, produces a significant reduction in obesity and vascular and inflammatory complications in obese mice.

22 Apr 2020

Coumarin derivatives are synthesized using green chemistry methods

Coumarin derivatives (coumarins) are a class of compounds with a wide range of biological activities, which have found their application in medicine, pharmacology, cosmetics and food industry. Coumarin is found in a number of plants such as tonka beans and vanilla grass, among others.

21 Apr 2020

Discovery could open door to the development of new anti-cancer drugs

A team of scientists led by the University of Michigan Rogel Cancer Center and Case Comprehensive Cancer Center has identified the binding site where drug compounds could activate a key braking mechanism against the runaway growth of many types of cancer.

20 Apr 2020

Using genome-wide CRISPR technology to identify leukemia's weakness

A team of researchers at University of California San Diego School of Medicine and Moores Cancer Center used CRISPR technology to identify key regulators of aggressive chronic myeloid leukemia, a type of cancer that remains difficult to treat and is marked by frequent relapse.

20 Apr 2020

Penn Medicine launches convalescent plasma therapy trial for COVID-19 patients

Convalescent plasma therapy for COVID-19 patients -- an experimental approach of giving a transfusion of plasma collected from a donor who has recovered from COVID-19 to a patient with an active infection -- is the focus of a new two-part research initiative at Penn Medicine.

20 Apr 2020

Activating a braking mechanism against cancer

A team has identified the binding site where drug compounds could activate a braking mechanism against runaway growth of cancer.

20 Apr 2020

Scientists discover anti-cancer compound in the humble willow

More than a century after giving the world aspirin, another potential drug has been found in the stem and leaves of willows – this time with anti-cancer properties.

17 Apr 2020

Regular exercise may reduce risk of deadly complication in patients with COVID-19

Regular exercise may reduce the risk of acute respiratory distress syndrome, a major cause of death in patients with the COVID-19 virus, a top exercise researcher reports.

15 Apr 2020

Researchers decode how immune sensor plays role in defending cells against intruders

Until now, the immune sensor TLR8 has remained in the shadows of science. A research team led by the University of Bonn has now discovered how this sensor plays an important role in defending human cells against intruders.

15 Apr 2020

Harnessing power of cancer gene could lead to first curative treatment for heart disease

Researchers trying to turn off a gene that allows cancers to spread have made a surprising U-turn. By making the gene overactive and functional in the hearts of mice, they have triggered heart cell regeneration.

15 Apr 2020

Temple researchers receive NIAID grant to study immunological synapse formation

Switching immune cells on is a critical step in combating infection. In the case of T cells, which are key players in immunity, this happens when dormant T cells circulating in the blood encounter a suspicious agent on the surface of specialized antigen-presenting cells.

14 Apr 2020

WVU researchers develop viable alternatives to N95 masks

The novel coronavirus pandemic has nearly exhausted stockpiles of medical gear in the United States. Personal protective equipment, like masks, serve as a first-line defense for medical professionals with a front row seat to COVID-19.

13 Apr 2020

Mechanical ventilators based on a simple modification of CPAP and BiPAP machines

As hospitals in New York City and beyond are facing a shortage of mechanical ventilators for COVID-19 patients in critical care, many are turning to readily available CPAP and BiPAP machines as a measure.

10 Apr 2020

Modifiable risk factors could play important role in Alzheimer's disease, study finds

Amyloid is a key feature of Alzheimer's disease, but the accumulation of these sticky proteins may not be the only risk factor for developing Alzheimer's disease, according to a new study published this week.

8 Apr 2020

Potential harms associated with some drugs used for treating COVID-19 patients

Chloroquine, hydroxychloroquine and azithromycin are being used to treat and prevent COVID-19 despite weak evidence for effectiveness, and physicians and patients should be aware of the drugs' potentially serious adverse events, states a review in CMAJ.

8 Apr 2020

Study compares health of pregnant and non-pregnant women with IBD

Inflammatory bowel disease--including Crohn's disease and ulcerative colitis--often affects women of childbearing age.

8 Apr 2020

A special diet can help in certain cases of asthma, study suggests

Can a special diet help in certain cases of asthma? A new study at the University of Bonn at least points to this conclusion. According to the study, mice that were switched to a so-called ketogenic diet showed significantly reduced inflammation of the respiratory tract.

7 Apr 2020

Metrion Biosciences and International Scientific Consortium publish data and new recommendations for in vitro risk assessment of the cardiac safety of new medicines

Metrion today announced it has contributed to two new peer-reviewed papers under the U.S. FDA CiPA (Comprehensive in vitro Proarrhythmia Assay) initiative.

From Metrion Biosciences Limited 7 Apr 2020

Researchers make breakthrough in unlocking genetic potential of ocean microbes

Researchers have made a breakthrough in developing gene-editing tools to improve understanding of an important ocean microbe.

6 Apr 2020

Pharmacology News and Research

Latest Pharmacology News and Research

Study reveals potential therapeutic target for treating cocaine addiction

Study: Orujo Olive OIL reduces obesity and inflammatory complications in obese mice

Coumarin derivatives are synthesized using green chemistry methods

Discovery could open door to the development of new anti-cancer drugs

Using genome-wide CRISPR technology to identify leukemia's weakness

Penn Medicine launches convalescent plasma therapy trial for COVID-19 patients

Activating a braking mechanism against cancer

Scientists discover anti-cancer compound in the humble willow

Regular exercise may reduce risk of deadly complication in patients with COVID-19

Researchers decode how immune sensor plays role in defending cells against intruders

Harnessing power of cancer gene could lead to first curative treatment for heart disease

Temple researchers receive NIAID grant to study immunological synapse formation

WVU researchers develop viable alternatives to N95 masks

Mechanical ventilators based on a simple modification of CPAP and BiPAP machines

Modifiable risk factors could play important role in Alzheimer's disease, study finds

Potential harms associated with some drugs used for treating COVID-19 patients

Study compares health of pregnant and non-pregnant women with IBD

A special diet can help in certain cases of asthma, study suggests

Metrion Biosciences and International Scientific Consortium publish data and new recommendations for in vitro risk assessment of the cardiac safety of new medicines

Researchers make breakthrough in unlocking genetic potential of ocean microbes

Pittcon Highlights: Pharmaceutical & Biologic eBook

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

Pharmacology News and Research

Latest Pharmacology News and Research

Pittcon Highlights: Pharmaceutical & Biologic eBook

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

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