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SigRM offers breakthrough in single-cell epitranscriptomics analysis

Researchers have developed a new tool that will help scientists study how genes are expressed in our cells.

6 Dec 2024

New method detects unrecognized chemicals in the human body

From the 1960s to the 1980s, the use of lead in fuel, paints, and pipes caused widespread contamination.

6 Dec 2024

Reimagining axons with the pearls-on-a-string model

In a provocative new study, scientists challenge a fundamental tenet in neuroscience about the shape of axons -- the long, thin filaments radiating from nerve cells that transmit electrical signals from cell to cell – and propose a new model for understanding how information is transmitted in the brain.

6 Dec 2024

Breakthrough in HWE reaction offers pathway for anti-cancer drug development

The Horner–Wadsworth–Emmons (HWE) reaction is a fundamental reaction in organic chemistry, widely used to create conjugated carbonyl compounds.

6 Dec 2024

Researchers map the circadian clock in the fly brain

All animals including humans are subject to daily rhythms in their activity and sleep, hunger, metabolism, and reproduction.

6 Dec 2024

Extracellular vesicle DNA regulates immune responses and suppresses liver metastasis

The study highlights how EV-DNA packaging influences immune responses and its promise as a biomarker for assessing colorectal cancer metastasis risk.

6 Dec 2024

New computational pipeline identifies key biomarkers for Alzheimer's disease

Researchers at Columbia University Mailman School of Public Health have developed a novel computational pipeline designed to identify protein biomarkers associated with complex diseases, including Alzheimer's disease (AD).

6 Dec 2024

Study sheds light on Kif23's role in embryonic brain development and microcephaly

A team of researchers from Tohoku University, the National Center of Neurology and Psychiatry, and National Yang Ming Chiao Tung University has uncovered a novel molecular mechanism through which Kif23 (a motor protein belonging to the kinesin family) plays a vital role in embryonic brain development.

5 Dec 2024

New framework enhances genetic prediction of drug response and side effects

A UCLA study has outlined a new framework that researchers say would improve predictive power of genetics to determine how well a patient would respond to commonly prescribed medications as well as the severity of any side effects.

5 Dec 2024

PAGER technology unlocks new potential for controlling cellular activity

A basic function of cells is that they act in response to their environments. It makes sense, then, that a goal of scientists is to control that process, making cells respond how they want to what they want.

5 Dec 2024

Study uncovers dangerous side effects of AZD7648 in gene editing

Genome editing with various CRISPR-Cas molecule complexes has progressed rapidly in recent years.

5 Dec 2024

Discovery of leptin-responsive neurons offers new hope for obesity treatment

Obesity affects a staggering 40 percent of adults and 20 percent of children in the United States. While some new popular therapies are helping to tackle the epidemic of obesity, there is still so much that researchers do not understand about the brain-body connection that regulates appetite.

5 Dec 2024

MGI Tech’s Innovative Sequencing Technology Drives Mangrove Conservation Efforts in Thailand

MGI Tech partners with NOC to leverage advanced sequencing for mangrove conservation, addressing environmental challenges and enhancing ecosystem resilience.

From MGI 5 Dec 2024

Gut microbiome and brain evolution: New insights into energy allocation

Gut microbiota from primates with larger brains promotes glucose production and energy allocation for brain function, shedding light on metabolic strategies in evolution.

4 Dec 2024

Alzheimer's genetic risk studies undermined by systemic biases

Recent research in Nature Genetics reveals pervasive biases in GWAX studies using parental history of Alzheimer’s, highlighting potential misdirection in genetic associations and disease risk predictions. A novel GSUB method identifies false signals stemming from confounding factors like survival bias and socioeconomic status.

4 Dec 2024

Immune cells play a key role in movement control and metabolic balance

Immune cells have a surprising and critical role in controlling movement and bridging neural activity with metabolic demands, concludes a groundbreaking study published in Nature by researchers at the University of Copenhagen and Imperial College London.

4 Dec 2024