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New gene editing tool enables precise control of mitochondrial mutation load

Mitochondrial diseases affect approximately 1 in 5,000 people worldwide, causing debilitating symptoms ranging from muscle weakness to stroke-like episodes.

3 May 2025

RNA editing enzyme found to trigger neuroinflammation in Parkinson's

Parkinson's disease (PD) is a neurodegenerative disorder in which the α-synuclein protein abnormally aggregates within brain cells, causing neuronal damage.

3 May 2025

Medicaid enrollment drops linked to disrupted care for young people

Children and young adults with depression, schizophrenia, ADHD, asthma and epilepsy can get great relief from medications to control their symptoms, helping them stay in school or work and prepare for their futures.

3 May 2025

New three-part antivenom cocktail protects against the world’s deadliest snakes

Scientists developed a groundbreaking antivenom cocktail using antibodies from a hyperimmune human donor and a small-molecule inhibitor that protected mice from deadly bites of 19 diverse snakes. This approach could lead to a universal antivenom for the world’s most dangerous snakes, overcoming the limitations of current species-specific treatments.

2 May 2025

Are one-year-olds in Australia eating right? New study reveals nutrient gaps

A study from the ORIGINS cohort in Western Australia assessed the diets of one-year-old children, comparing intake to national guidelines. While most nutrient targets were met, key shortfalls in iodine and excessive sodium intake raised concerns, especially for breastfed infants.

2 May 2025

Study shows brain estrogen directly regulates appetite in mice

Researchers in Japan found that estrogen produced within the brain, called neuroestrogen, suppresses appetite and reduces body weight in mice by enhancing MC4R expression. The study also showed that neuroestrogen boosts leptin sensitivity, suggesting new targets for obesity treatment.

2 May 2025

MRI technique reveals the heart's functional age

Scientists at the University of East Anglia (UEA) have developed a revolutionary new way of uncovering the 'true age' of your heart using MRI.

2 May 2025

Stenting improves long term outcomes in CTO PCI patients

In patients undergoing chronic total occlusion (CTO) percutaneous coronary intervention (PCI), stenting demonstrated improved long-term survival and fewer cardiac arrests at one year.

2 May 2025

Heat triggers sperm activation for fertilization in mammals

In mammals - including us humans - sperm are surprisingly picky about temperature, thriving best in conditions a few degrees cooler than normal body temperature.

2 May 2025

New imaging technique reveals live neural activity in deep brain regions

The communication between the brain and bodily organs is fundamental to emotion regulation and overall mental health.

2 May 2025

Early TAVR shows greatest stroke reduction in patients aged 65 to 70

New analysis from the EARLY TAVR trial showed patients between the age of 65 and 70 years old derived the most benefits of a strategy of early intervention with transcatheter aortic valve replacement (TAVR) compared to other age groups, especially in regards to stroke risk, and in regards to the composite of death, stroke, and heart failure hospitalization.

2 May 2025

HO-1 regulates liver fibrosis in NAFLD through the SIRT1 TGF-β Smad3 pathway

Heme oxygenase 1 (HO-1) has an influential yet insufficiently investigated effect on Sirtuin 1 (SIRT1), a histone deacetylase activated by nicotinamide adenine dinucleotide, which may impact the transforming growth factor-β (TGF-ß)/Smad3 pathway in nonalcoholic fatty liver disease (NAFLD)-related liver fibrosis.

2 May 2025

Hairlike electrodes offer a new era for comfortable EEG monitoring

The future of electroencephalography (EEG) monitoring may soon look like a strand of hair. In place of the traditional metal electrodes, a web of wires and sticky adhesives, a team of researchers from Penn State created a hairlike device for long-term, non-invasive monitoring of the brain's electrical activity.

2 May 2025

New albumin-based vaccine shows promise for mucosal immunity

Vaccines save millions of lives every year, but there is still an urgent need for more efficient vaccines. Strategies to combat serious outbreaks of viral infections are particularly important.

2 May 2025

Medicaid rollbacks could deepen health inequities

A new analysis provides evidence that reductions in access to Medicaid could increase deaths and cause financial hardship to people currently covered under an expansion of Medicaid that was implemented under the Affordable Care Act (ACA).

2 May 2025

New insights into facial bacteria may improve acne treatment strategies

The composition of bacterial populations living on our faces plays a significant role in the development of acne and other skin conditions such as eczema.

2 May 2025

Single antiplatelet therapy after TAVR linked to lower mortality and bleeding

Findings from the Transfusion Requirements in Transcatheter Aortic Valve Implantation (TRITAVI) registry demonstrate that single antiplatelet therapy (SAPT) after transcatheter aortic valve replacement (TAVR) is associated with a significantly lower incidence of six-month mortality and major bleeding risk compared to dual antiplatelet therapy (DAPT).

2 May 2025

Study shows safe outcomes for PCI performed in ambulatory surgery centers

The first study evaluating Medicare patients undergoing percutaneous coronary intervention (PCI) in ambulatory surgery centers (ASCs) demonstrated good safety outcomes, such as mortality and adverse event rates at 30 days, compared to outpatient hospital departments, but were less likely to use certain technologies.

2 May 2025

Study uncovers how a mobile genetic element hijacks human cells

Viruses are known to use the genetic machinery of the human cells they invade to make copies of themselves. As part of the process, viruses leave behind remnants throughout the genetic material (genomes) of humans.

2 May 2025

Addressing the urgent health and environmental threat from endocrine disrupting chemicals

Taking place on 14 May 2025, in Copenhagen and online, the event will bring together leading European scientists, policymakers and civil society to address the urgent health and environmental threat from endocrine disrupting chemicals (EDCs).

2 May 2025