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Breakthrough technology enables mRNA delivery across the blood-brain barrier

Scientists at the Icahn School of Medicine at Mount Sinai have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a challenge that has long been limited by the protective nature of the blood-brain barrier.

17 Feb 2025

ICHOM develops standard dataset that defines heart valve disease outcomes

The International Consortium for Health Outcomes Measurement (ICHOM) has developed a globally inclusive standard dataset of 16 patient-centered outcome measures for people with heart valve disease, regardless of treatment (surgical or transcatheter procedure), according to a new report published today in the American Heart Association's journal Circulation: Cardiovascular Quality & Outcomes.

17 Feb 2025

Therapy dogs help first-year students cope with stress, depression, and anxiety

Therapy dog programs show promise in supporting university students' mental health, reducing anxiety and depression during their first semester adjustments.

17 Feb 2025

Can AI be your therapist? Study shows ChatGPT outperforms professionals in key areas

AI-assisted mental health care is evolving, with ChatGPT-4 outperforming therapists in empathy and cultural competence, raising implications for psychotherapy.

17 Feb 2025

Can changing how we think about being alone reduce loneliness?

Researchers found that negative media portrayals of being alone increase loneliness by shaping harmful beliefs, while positive portrayals reduce loneliness, a pattern observed across nine countries.

16 Feb 2025

Obesity and cognition: Surprising study links higher BMI to better memory

Higher BMI in early adulthood and midlife is linked to better memory performance, particularly in men and Black Americans, challenging traditional views on obesity and cognition.

16 Feb 2025

Diabetes drugs may boost brain health but experts warn of risks

Researchers reviewed 374 studies to explore how GLP-1RAs, originally for diabetes, may impact brain health, finding potential benefits for dementia and addiction but inconsistent results for mood disorders.

16 Feb 2025

Vaping and gum health: How does it compare to smoking?

A systematic review found that e-cigarette users show increased plaque and inflammation markers compared to non-smokers, though their gum health fares better than traditional smokers. However, the certainty of these findings is low due to study bias.

16 Feb 2025

ADHD symptoms increase risk of e-cigarette and tobacco use in U.S. youths

A new study finds that U.S. youths with symptomatic ADHD are significantly more likely to initiate e-cigarette and tobacco use over time, highlighting the need for early intervention and effective ADHD management.

16 Feb 2025

Novel method for generating antibodies could revolutionize Alzheimer's and Parkinson's research

In diseases like Parkinson's and Alzheimer's, specific proteins misfold and clump together, forming toxic aggregates that damage brain cells.

16 Feb 2025

New research sheds light on brain inflammation in Alzheimer's

Brain inflammation, while a crucial part of the body's immune response, takes on a detrimental role in Alzheimer's disease.

16 Feb 2025

Gene therapy shows promise in treating SCN1B-linked epileptic encephalopathies

Dravet syndrome and other developmental epileptic encephalopathies are rare but devastating conditions that cause a host of symptoms in children, including seizures, intellectual disability, and even sudden death.

14 Feb 2025

Prozac's surprising immune-boosting effects could lead to new treatments for sepsis

Antidepressants like Prozac are commonly prescribed to treat mental health disorders, but new research suggests they could also protect against serious infections and life-threatening sepsis.

14 Feb 2025

Study reveals key role of opsin 3 in regulating food intake and energy balance

Scientists discovered years ago that the hypothalamus - which helps to manage body temperature, hunger, sex drive, sleep and more - includes neurons that express the protein opsin 3 (OPN3).

14 Feb 2025

Innovative blood test shows potential to replace spinal tap for Alzheimer's diagnosis

Up to half of all people living with Alzheimer's Disease in Ireland remain undiagnosed. Now, a new blood test may have the potential to transform patient care, allowing for better diagnosis, earlier interventions and more targeted treatments.

14 Feb 2025

Sotagliflozin could be used to reduce the risk of deadly cardiovascular events, trial shows

Sotagliflozin, a drug recently approved by the Food and Drug Administration to treat type 2 diabetes and kidney disease with additional cardiovascular risk factors, can significantly reduce heart attack and stroke among these patients, according to results from an international clinical trial led by a Mount Sinai researcher.

14 Feb 2025

New global guideline for Candida infections sets standards for diagnosis and treatment

Together with a team of international clinical researchers, Professor Dr Oliver A. Cornely and Dr Rosanne Sprute from University Hospital Cologne have published the new global guideline for the diagnosis and treatment of Candida infections.

14 Feb 2025

2024 CSCO Breast Cancer guidelines revolutionize treatment approaches in China

Breast cancer remains a major global health challenge, with treatment strategies varying widely across regions.

14 Feb 2025

UVA receives $9.3 million NIH grant for ketamine seizure treatment trial

University of Virginia Brain Institute and School of Medicine researchers have received an initial $9.3 million award from the National Institutes of Health for a $30 million clinical trial to determine if the powerful anesthetic ketamine can save patients from prolonged, life-threatening grand mal seizures that won't respond to other treatments.

14 Feb 2025

Duke and Duke-NUS collaborate to fund innovative climate health research projects

Duke University and Duke-NUS Medical School are proud to announce the recipients of their latest Research Collaboration Pilot Project grants, totalling more than S$1 million.

14 Feb 2025

Medical News

Breakthrough technology enables mRNA delivery across the blood-brain barrier

ICHOM develops standard dataset that defines heart valve disease outcomes

Therapy dogs help first-year students cope with stress, depression, and anxiety

Can AI be your therapist? Study shows ChatGPT outperforms professionals in key areas

Can changing how we think about being alone reduce loneliness?

Obesity and cognition: Surprising study links higher BMI to better memory

Diabetes drugs may boost brain health but experts warn of risks

Vaping and gum health: How does it compare to smoking?

ADHD symptoms increase risk of e-cigarette and tobacco use in U.S. youths

Novel method for generating antibodies could revolutionize Alzheimer's and Parkinson's research

New research sheds light on brain inflammation in Alzheimer's

Gene therapy shows promise in treating SCN1B-linked epileptic encephalopathies

Prozac's surprising immune-boosting effects could lead to new treatments for sepsis

Study reveals key role of opsin 3 in regulating food intake and energy balance

Innovative blood test shows potential to replace spinal tap for Alzheimer's diagnosis

Sotagliflozin could be used to reduce the risk of deadly cardiovascular events, trial shows

New global guideline for Candida infections sets standards for diagnosis and treatment

2024 CSCO Breast Cancer guidelines revolutionize treatment approaches in China

UVA receives $9.3 million NIH grant for ketamine seizure treatment trial

Duke and Duke-NUS collaborate to fund innovative climate health research projects

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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