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Restoring youthful TERT levels reverses aging phenotypes in preclinical models

Researchers at The University of Texas MD Anderson Cancer Center have demonstrated that therapeutically restoring 'youthful' levels of a specific subunit of the telomerase enzyme can significantly reduce the signs and symptoms of aging in preclinical models.

21 Jun 2024

Transforming drug discovery with AI

A new AI-powered program will allow researchers to level up their drug discovery efforts.

21 Jun 2024

Insilico Medicine leadership team shares insights on AI-powered healthcare innovation

Insilico Medicine ("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, announces that the co-CEOs of the company – Alex Zhavoronkov, PhD, and Feng Ren, PhD – will be attending the 15th Annual Meeting of the New Champions, also known as Summer Davos hosted by the World Economic Forum, in Dalian, China, from 25 to 27 June 2024.

21 Jun 2024

ALS: Newly discovered subtypes and sex differences create new approaches for drugs

Amyotrophic lateral sclerosis, ALS for short, is a mysterious neurodegenerative disease that is almost always fatal.

21 Jun 2024

UCF researcher further explores nanotech to improve cancer and disease detection

Early discovery of debilitating diseases such as cancer or dementia is critical in determining treatment and saving lives.

21 Jun 2024

Study reveals critical role of ADGRF5 in maintaining glomerular filtration barrier integrity

Glomerulus, the fundamental filtering unit of the kidney, is an intricate network of capillaries - small blood vessels that regulate the movement of ions, water, and metabolites while maintaining impermeability to essential macromolecules such as proteins.

21 Jun 2024

Regular IgG monitoring and replacement therapy reduce severe infections in CLL and NHL patients

Patients with chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphomas (NHLs) who received frequent tests for immunoglobulin G (IgG) were less likely to experience severe infections compared with those who didn't, according to a study published in Blood Advances.

21 Jun 2024

High-resolution structures of SSTR5 reveal key interactions with neuropeptide and drug agonists

Somatostatin receptors (SSTRs) constitute a crucial family of G protein-coupled receptors (GPCRs) that play pivotal roles in regulating hormone secretion and inhibiting tumor growth.

21 Jun 2024

New insights into signaling pathways and resistance mechanisms in colorectal cancer

Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. The complexity of its pathogenesis, involving genetic mutations, dysregulated signaling pathways, and compromised immune surveillance, presents significant challenges for effective treatment.

21 Jun 2024

Anakinra shows promise in reducing symptoms in patients with Sanfilippo syndrome

As a neurodegenerative disease characterized by childhood onset dementia, Sanfilippo syndrome causes immense suffering in many ways, including pain, loss of speech, extreme agitation, and distress, gastrointestinal symptoms, and profound sleep disturbance.

21 Jun 2024

Bariatric surgery lowers heart risks and death rates in obese patients with sleep apnea

A Cleveland Clinic study shows that bariatric surgery performed in patients with obesity and moderate to severe obstructive sleep apnea is associated with a significantly lower risk of death and major adverse cardiovascular events, compared with patients who did not have the surgery.

21 Jun 2024

Repurposing anti-retroviral medications for brain tumor treatment: The RETREAT trial

Drugs developed to combat HIV and AIDS are being trialed for the first time in patients with multiple brain tumors.

21 Jun 2024

Expert consensus and guidance for integrating discussions of racism in pediatric care

Extensive research shows the link between exposure to racism during childhood and adolescence and increased risks of depression and metabolic health issues, such as obesity, diabetes and heart disease.

21 Jun 2024

Study links lifetime cannabis use with substance use, mood disorders, celiac, and infectious diseases

Researchers identify genetic loci associated with lifetime and frequency of cannabis use.

21 Jun 2024

Super Bowl parade shooting survivors await promised donations while bills pile up

Abigail Arellano keeps her son Samuel's medical bills in a blue folder in a cabinet above the microwave. Even now, four months after the 11-year-old was shot at the Kansas City Chiefs Super Bowl parade, the bills keep coming.

21 Jun 2024

How micro- and nanoplastics may worsen non-communicable diseases

Researchers review and assess the potential exacerbation of non-communicable diseases by micro- and nanoplastics.

21 Jun 2024

Can cocoa lower your heart disease risk?

Researchers review the effects of cocoa consumption on the risk of cardiovascular disease.

21 Jun 2024

Semaglutide weight loss results linked to diabetes severity

Researchers investigate the weight loss outcomes of semaglutide treatment in obese patients with type 2 diabetes.

21 Jun 2024

SuperAnimal: A deep learning model for automated animal behavior analysis

Behavioral analysis can provide a lot of information about the health status or motivations of a living being.

21 Jun 2024

Using deep learning to design synthetic soluble versions of cell membrane proteins

Many drug and antibody discovery pathways focus on intricately folded cell membrane proteins: when molecules of a drug candidate bind to these proteins, like a key going into a lock, they trigger chemical cascades that alter cellular behavior.

21 Jun 2024

Medical News

Restoring youthful TERT levels reverses aging phenotypes in preclinical models

Transforming drug discovery with AI

Insilico Medicine leadership team shares insights on AI-powered healthcare innovation

ALS: Newly discovered subtypes and sex differences create new approaches for drugs

UCF researcher further explores nanotech to improve cancer and disease detection

Study reveals critical role of ADGRF5 in maintaining glomerular filtration barrier integrity

Regular IgG monitoring and replacement therapy reduce severe infections in CLL and NHL patients

High-resolution structures of SSTR5 reveal key interactions with neuropeptide and drug agonists

New insights into signaling pathways and resistance mechanisms in colorectal cancer

Anakinra shows promise in reducing symptoms in patients with Sanfilippo syndrome

Bariatric surgery lowers heart risks and death rates in obese patients with sleep apnea

Repurposing anti-retroviral medications for brain tumor treatment: The RETREAT trial

Expert consensus and guidance for integrating discussions of racism in pediatric care

Study links lifetime cannabis use with substance use, mood disorders, celiac, and infectious diseases

Super Bowl parade shooting survivors await promised donations while bills pile up

How micro- and nanoplastics may worsen non-communicable diseases

Can cocoa lower your heart disease risk?

Semaglutide weight loss results linked to diabetes severity

SuperAnimal: A deep learning model for automated animal behavior analysis

Using deep learning to design synthetic soluble versions of cell membrane proteins

How can super-resolution technology help study neurotransmission?

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

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