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Integrating PGx testing for personalized prostate cancer treatment

Prostate cancer (PC) is a significant health concern, being the second leading cause of death among American men.

31 May 2024

Super-resolution microscopy offers high-resolution view of virus replication inside cells

A new, nano-scale look at how the SARS-CoV-2 virus replicates in cells may offer greater precision in drug development, a Stanford University team reports in Nature Communications.

31 May 2024

New vessel-chip deployment platform holds promise for personalized drug testing

The pharmaceutical drug development and approval process is a multi-step undertaking that requires a plethora of testing before reaching the market.

31 May 2024

Stress and pain linked to worse outcomes in HER2-positive breast cancer patients

Secondary analyses of a phase 3 clinical trial have revealed that breast cancer patients who reported high levels of pain and stress were more likely than their study peers to experience worse invasive disease-free survival (iDFS) and worse overall survival (OS).

31 May 2024

Weakening credit scores and rising delinquency may be warning signs of undiagnosed memory disorders

In the years prior to an Alzheimer's disease or other memory disorder diagnosis, credit scores begin to weaken and payment delinquency begins to increase, concludes new research led by Georgetown University.

31 May 2024

Breakthrough CAR T therapy and shorter targeted therapy durations offer hope for patients with leukemia

The novel anti-CD19 autologous chimeric antigen receptor (CAR) T cell therapy obecabtagene autoleucel (obe-cel) achieved durable remissions in 40% of patients with relapsed or refractory B-ALL without a subsequent stem cell transplant (SCT), according to results from the Phase Ib/II FELIX clinical trial presented today by Elias Jabbour, M.D., professor of Leukemia.

31 May 2024

Eye-tracking technology offers earlier, more accurate autism diagnosis

Nearly 3% of all children in the United States are diagnosed with autism, according to the Centers for Disease Control and Prevention.

31 May 2024

Polygenic risk score shows potential to predict survival outcomes in breast cancer patients

Data from a large prospective cohort study reveal that a polygenic risk score has the potential to predict survival outcomes in patients with breast cancer.

31 May 2024

Mindfulness as medicine: A powerful tool for pain and addiction

Mindfulness training has made its way into school districts, self-help and health books, and workplaces. One day soon, it could also be widely offered as a "medicine" for some physical and mental health conditions.

31 May 2024

Synthetic cartilage plugs may help heal osteochondral defects and avoid total knee replacements

Osteochondral defects (OCDs) can cause damage to cartilage and underlying bone, leading to chronic pain and loss of joint function.

31 May 2024

VUMC researchers discover potent antibody against influenza B

Researchers at Vanderbilt University Medical Center have isolated human monoclonal antibodies against influenza B, a significant public health threat that disproportionately affects children, the elderly and other immunocompromised individuals.

31 May 2024

Conscience and care: Physicians' ethical barriers to medical aid in dying

Recently published research led by the University of Colorado Anschutz Medical Campus examined the prevalence - and impact - of physicians' ethical or religious barriers to their involvement in medical aid in dying (MAiD), a multi-step process where a physician provides a terminally ill adult with decision-making capacity with a lethal dose of medication to end their life.

31 May 2024

Ketones show promise in preventing cognitive decline and neurodegeneration

Researchers at the Del Monte Institute for Neuroscience at the University of Rochester have identified mechanisms in the brain's hippocampal network that are rescued by ketones.

31 May 2024

From ancient remedies to modern medicine: Inorganic materials offer new hope for tissue regeneration

For centuries, civilizations have used naturally occurring, inorganic materials for their perceived healing properties.

31 May 2024

Study: 13% of older adults diagnosed with traumatic brain injury

Some 13% of older adults are diagnosed with traumatic brain injury (TBI), according to a study by UC San Francisco and the San Francisco VA Health Care System

31 May 2024

Non-coding gene mutation linked to monogenic neurodevelopmental disorders

Researchers at the Icahn School of Medicine at Mount Sinai and others have identified a neurodevelopmental disorder, caused by mutations in a single gene, that affects tens of thousands of people worldwide.

31 May 2024

Mediterranean diet linked to lower mortality risk in women

Investigators from Brigham and Women's Hospital identified and assessed underlying mechanisms that may explain the Mediterranean diet's 23 percent reduction in all-cause mortality risk for American women.

31 May 2024

Survey: 82.7 million Americans impacted by overdose deaths

Losing a loved one to drug overdose has been a common experience for many Americans in recent years, crossing political and socioeconomic divides and boosting the perceived importance of the overdose crisis as a policy issue, according to a new survey led by researchers at the Johns Hopkins Bloomberg School of Public Health.

31 May 2024

RNA virus hiding in common human parasite may exacerbate toxoplasmosis

An international team led by researchers at the University of Toronto has found a new RNA virus that they believe is hitching a ride with a common human parasite.

31 May 2024

Novel electromagnetic system for safer intraocular surgery

The electromagnetic driving systems are proposed for the flexible 5-DOF magnetic manipulation of a micro-robot within the posterior eye, enabling precise targeted drug delivery.

31 May 2024