Simulations Plus, Inc. (Nasdaq: SLP), the leading provider of simulation 
      and modeling software for pharmaceutical discovery and development, 
      announced today that its board of directors has authorized a renewed 
      share repurchase program effective Monday, February 15, 2010.
    
    
      Ms. Momoko Beran, chief financial officer of Simulations Plus, said: 
      “The board of directors has decided to restart our share repurchase 
      program, enabling the buyback of up to one million shares during a 
      12-month period beginning Monday, February 15, 2010. Repurchases may be 
      made in the open market, through a broker, or through privately 
      negotiated transactions, subject to market conditions, applicable legal 
      requirements and other factors. Simulations Plus has no obligation to 
      repurchase shares under the repurchase program and the timing, actual 
      number, and price of shares to be purchased will depend on the 
      performance of Simulations Plus' stock price, general market conditions, 
      and various other factors. Such purchases, if any, will be made in 
      accordance with applicable insider trading and other securities laws and 
      regulations within the discretion of management.”
    
    
      Walt Woltosz, chairman and chief executive officer of Simulations Plus, 
      added: “At this time, the board believes that the continued 
      undervaluation of our stock and the continued growth of our cash, 
      warrants continuing the share repurchase program we had during December 
      2008 to December 2009, subject to management’s discretion and market 
      conditions as Ms. Beran has described. Authorizing this amount is not 
      expected to interfere with potential acquisitions or with meeting 
      operating requirements, which the board believes are of utmost priority.”