Study finds pleasurable music and 'chills' predict music-induced hypoalgesia

In a study published in Frontiers in Pain Research, researchers showed that emotional responses to relaxing and favorite music predict hypoalgesia.

Study: Emotional responses to favorite and relaxing music predict music-induced hypoalgesia. Image Credit: Stokkete/
Study: Emotional responses to favorite and relaxing music predict music-induced hypoalgesia. Image Credit: Stokkete/

Music can reduce anxiety and pain in patients, albeit the underlying mechanisms remain poorly defined. Pain remains a significant individual and societal burden, warranting alternatives without heavily relying on pharmacological analgesics. As such, music may represent a viable non-pharmacological intervention.

Further, subject-preferred music appears to induce a superior effect in relieving pain. This can be approached by allowing participants to select the most pleasant music from a prespecified list of songs or listen to their favorite music during the study. Nevertheless, the richness of emotions, meanings, and associations involved when listening to favorite music is poorly understood, especially regarding pain relief.

About the study

In the present study, researchers evaluated which subjective aspects of listening to relaxing and favorite music were crucial for hypoalgesia. Sixty-three healthy individuals, aged 21.3, on average, participated in this study. A thermal contact probe was used to induce painful thermal stimuli on the inner forearm surface.

Music tracks for the study were participants’ two favorite songs, each running at least three minutes and twenty seconds. Participants selected songs that would represent their all-time favorite music and were chosen by asking which tracks they would bring to a desert island. Additionally, relaxing music provided by a company was used. The experiment paired thermal stimulations with music excerpts.

The procedure included a series of seven-minute blocks, each representing different conditions, such as favorite music, relaxing music, scrambled versions, and silence. Each block comprised eight 50-second cycles of music and stimulation. During each cycle, music, silence, or scrambled music was played for 35 seconds, followed by stimulation for 15 seconds.

Participants rated the unpleasantness and intensity of the pain after each stimulation. Likewise, they indicated the number of chills, frissons, or thrills, emotional arousal, and pleasantness of the music. Participants were asked questions about their favorite songs/music at the end of the session. A thematic content analysis was performed to examine whether the absence or presence of specific themes moderated the effects of favorite music on pain ratings.

Favorite songs can reduce pain

The researchers noted that favorite music reduced the intensity and unpleasantness of the pain compared to scrambled music and silence. Relaxing music caused no significant reduction in pain intensity; however, the effect on unpleasantness approached significance. Further, favorite music significantly decreased pain relative to relaxing music. There were no significant differences between scrambled music and silence.

Music was perceived as more pleasant, producing more chills than scrambled versions. Besides, favorite music had higher average ratings on these measures than relaxing tracks. The incidence of chills influenced the unpleasantness and intensity of the pain. Meanwhile, the pleasantness of the music had no significant effect on pain intensity. Emotional arousal ratings did not affect pain.

The team performed mediation analyses to test whether emotion could explain the difference in effect between relaxing and favorite music. They observed a significant indirect effect on pain intensity and unpleasantness through chills. However, there was no significant effect of music pleasantness on pain unpleasantness. Theme analysis revealed 17 themes centered on listening time (4 themes), activities (3), emotion (4), musical aspects (2), or associations (4).

Further analyses were focused on the four emotion themes – calming/relaxing, energizing/activating, moving/bittersweet, and happy/cheerful. Happiness was the most frequent emotion theme, with subjects frequently reporting that music made them happy. Moving/bittersweet music did not have a concrete purpose, like reducing anxiety, improving mood, or increasing energy.

There was a near-significant effect of moving/bittersweet music on pain unpleasantness ratings, whereas calming/relaxing music had no significant impact. Other themes had no apparent effect. In addition, a second mediation analysis investigated whether the impact of emotional themes could be explained by subjective emotions (chills, pleasantness, and emotional arousal).

The moving/bittersweet theme significantly predicted subjective emotions. On the other hand, there was a negative association between chills and happy/cheerful, energizing/activating, and relaxing/calming themes, and no association between emotional arousal or music pleasantness and these three themes.


Taken together, favorite music significantly reduced pain, unpleasantness, and intensity relative to silence and scrambled music, while relaxing music was less effective. The incidence of chills was a significant mediator of pain unpleasantness and intensity. Thus, a neuropsychological process underlying chills may exist, which might preferentially activate during favorite music. Moreover, moving/bittersweet music may have a superior effect in decreasing pain. Nevertheless, further research is needed to corroborate the findings.

Journal reference:
Tarun Sai Lomte

Written by

Tarun Sai Lomte

Tarun is a writer based in Hyderabad, India. He has a Master’s degree in Biotechnology from the University of Hyderabad and is enthusiastic about scientific research. He enjoys reading research papers and literature reviews and is passionate about writing.


Please use one of the following formats to cite this article in your essay, paper or report:

  • APA

    Sai Lomte, Tarun. (2023, October 31). Study finds pleasurable music and 'chills' predict music-induced hypoalgesia. News-Medical. Retrieved on February 29, 2024 from

  • MLA

    Sai Lomte, Tarun. "Study finds pleasurable music and 'chills' predict music-induced hypoalgesia". News-Medical. 29 February 2024. <>.

  • Chicago

    Sai Lomte, Tarun. "Study finds pleasurable music and 'chills' predict music-induced hypoalgesia". News-Medical. (accessed February 29, 2024).

  • Harvard

    Sai Lomte, Tarun. 2023. Study finds pleasurable music and 'chills' predict music-induced hypoalgesia. News-Medical, viewed 29 February 2024,


  1. Jeremy Beckman Jeremy Beckman United States says:

    I found it very interesting how much more prevalent chills are in the literature... As a young teen I'd experience them listening to some epic or moving music that really resonated with my emotional state, or by watching an epic scene in a movie. But it was rare to find others experiencing the same thing searching online or by asking friends. Maybe it's what others might describe as a profound or religious experience. All the hair on my arms stand up and I feel connected to a surge of energy from all around me... As if the inside of my body is vibrating with energy and emotion. A brief connection with the divine if you will.

  2. Susan Jacintho Susan Jacintho United States says:

    I read the whole article and still didn't know what it was until I web searched.  I would have listened more to what was written, but I was too busy looking for what hypoalgesia was, so the actual content was lost on me.  I even performed a document word search, in case it was defined and I'd missed it in, but there are 6 occurrences and no definitions.   Wikipedia told me this: Hypoalgesia or hypalgesia denotes a decreased sensitivity to painful stimuli...   of course I could glean this as implied from the many paragraphs in the article, but the burden for finding such things shouldn't be placed on the reader unless it's a mystery or a puzzle and intentionally obscure.

    Sincerely, a disappointed curmudgeon.

  3. Stephanie Last Stephanie Last United States says:

    I experience chills from music and it is usually coupled with euphoria.  It's not the same as what you get from opiates but I can see it working for pain a little.  I use music for anxiety but for it to work no one can talk to me and expect an answer because I gotta get lost in it.  Which would bring me back to why I can see it working for pain because if you aren't thinking about it it's not as intense.

The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News Medical.
Post a new comment
You might also like...
Breaking through new research barriers with iPSC technology