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Deep learning model predicts adverse drug reactions from chemical structure

Adverse drug reactions (ADRs) are a significant cause of hospital admissions and treatment discontinuation worldwide. Conventional approaches often fail to detect rare or delayed effects of medicinal products.

7 Aug 2025

New pH-responsive nanomaterials enhance precision drug delivery to tumors

Cancer remains one of the leading causes of death worldwide, and despite advancements in diagnosis and treatment, it continues to impose a significant health burden globally.

7 Aug 2025

Breakthrough in nanoparticle technology could expand access to biologic medicines

In a discovery that could broaden access to next-generation biologic medicines and vaccines, researchers at the University of Chicago Pritzker School of Molecular Engineering (UChicago PME) have engineered polymer-based nanoparticles that form with a simple temperature shift-no harsh chemicals, no specialized equipment, and no processing needed.

7 Aug 2025

Cherokee Nation Behavioral Health and Emory team up to prevent youth substance use

While overdose deaths in the U.S. sharply declined in 2024, they remain high. Almost 90,000 Americans died from drug overdoses between October 2023 and September 2024.

6 Aug 2025

RAND study highlights patterns of GLP-1 medication use and side effects

Nearly 12% of Americans have used GLP-1 drugs for weight loss, including about one-fifth of women aged 50 to 64, according to a new RAND report.

6 Aug 2025

Adolescents show lower rates of nonmedical ADHD drug use

Despite concerns about increased stimulant prescribing, nonmedical use of ADHD drugs among adolescents has declined in the last 20 years, a University of Michigan study shows.

6 Aug 2025

Targeted microglia replacement shows promise against fatal neurodegenerative conditions

Tay-Sachs and Sandhoff diseases, genetic disorders affecting the brain, have no effective treatment and are typically fatal within the first years of life.

6 Aug 2025

Many patients with high-risk myelodysplastic syndromes do not receive guideline-recommended treatment

Most patients with high-risk myelodysplastic syndromes (MDS) do not receive guideline-recommended treatment with hypomethylating agents (HMAs), according to results published in Blood Neoplasia.

6 Aug 2025

Alzheimer’s risk factors look different for men and women

Research on Alzheimer's risk factors shows significant sex differences, with implications for diagnosis and treatment in early-onset and late-onset cases.

6 Aug 2025

Nanoparticles could slow rheumatoid arthritis progression and reduce flare severity

As a chronic condition, rheumatoid arthritis (RA) can't be cured, so treatment focuses on managing the disease and controlling its progression. Although current treatments help control RA symptoms in most people, they cannot prevent the onset of RA or painful flare-ups.

6 Aug 2025

Gut microbiota and short chain fatty acids influence bone health in postmenopausal osteoporosis

Postmenopausal osteoporosis (PMOP) is framed as a systemic bone disease driven by estrogen withdrawal, but emerging evidence positions gut dysbiosis and its fermentation products—short-chain fatty acids (SCFAs)—as equally influential regulators of skeletal fate.

6 Aug 2025

New tool offers a more precise way to assess stroke risk in people with atrial fibrillation

Researchers at the University of Vermont have developed a more precise way to assess stroke risk in people with atrial fibrillation (A-Fib), a condition that affects 10.5 million Americans and is a leading cause of stroke.

6 Aug 2025

Low oxygen environment protects brain and restores movement in mice with Parkinson's

Researchers from the Broad Institute and Mass General Brigham have shown that a low-oxygen environment - similar to the thin air found at Mount Everest base camp - can protect the brain and restore movement in mice with Parkinson's-like disease.

6 Aug 2025

As California’s behavioral health workforce buckles, help is years away

This spring, the Good News Rescue Mission, which runs the only emergency homeless shelter in Shasta County, received a game-changing $17.8 million state grant to build a 75-bed residential treatment facility in a region where thousands struggle with drug and alcohol addiction.

6 Aug 2025

Magnesium deficiency drives higher mortality in hyperlipidemia

MgDS serves as a potential biomarker for mortality risk in hyperlipidemic adults, emphasizing the need for targeted approaches to manage cardiovascular health.

6 Aug 2025

Researchers question the historical basis of ancient psychedelic rituals

A new article in the peer-reviewed journal Psychedelic Medicine takes aim at one of the most influential, and controversial, narratives in comparative psychedelic culture: the idea that ancient Greek mystery rites at Eleusis were fueled by psychedelic drugs.

5 Aug 2025

Lupus Research Alliance awards early career scientists for innovative research

Today, the Lupus Research Alliance (LRA), the world's largest private funder of lupus research, announced the recipients of the 2025 Empowering Lupus Research (ELR) Career Development Award and Postdoctoral Award.

5 Aug 2025

Research offers hope for weight loss without gastrointestinal distress

Weight loss and diabetes drugs on the market often do not achieve long-term weight loss for patients. GLP-1 drugs target brain neurons that control appetite but frequently cause side effects.

5 Aug 2025

Weight loss with ozempic may weaken muscles even when size remains stable

As use of the popular anti-diabetic and weight-loss drug Ozempic skyrockets, so have concerns about the medication's side effects.

5 Aug 2025

KAIST scientists achieve first total synthesis of herpotrichone with neuroprotective properties

"Herpotrichone" is a natural substance that has been evaluated highly for its excellent ability to suppress inflammation in the brain and protect nerve cells, displaying significant potential to be developed as a therapeutic agent for neurodegenerative brain diseases such as Alzheimer's disease and Parkinson's disease.

5 Aug 2025

Drugs News and Research

Deep learning model predicts adverse drug reactions from chemical structure

New pH-responsive nanomaterials enhance precision drug delivery to tumors

Breakthrough in nanoparticle technology could expand access to biologic medicines

Cherokee Nation Behavioral Health and Emory team up to prevent youth substance use

RAND study highlights patterns of GLP-1 medication use and side effects

Adolescents show lower rates of nonmedical ADHD drug use

Targeted microglia replacement shows promise against fatal neurodegenerative conditions

Many patients with high-risk myelodysplastic syndromes do not receive guideline-recommended treatment

Alzheimer’s risk factors look different for men and women

Nanoparticles could slow rheumatoid arthritis progression and reduce flare severity

Gut microbiota and short chain fatty acids influence bone health in postmenopausal osteoporosis

New tool offers a more precise way to assess stroke risk in people with atrial fibrillation

Low oxygen environment protects brain and restores movement in mice with Parkinson's

As California’s behavioral health workforce buckles, help is years away

Magnesium deficiency drives higher mortality in hyperlipidemia

Researchers question the historical basis of ancient psychedelic rituals

Lupus Research Alliance awards early career scientists for innovative research

Research offers hope for weight loss without gastrointestinal distress

Weight loss with ozempic may weaken muscles even when size remains stable

KAIST scientists achieve first total synthesis of herpotrichone with neuroprotective properties

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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