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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Study provides insight into how low-dose ketamine alleviates symptoms of major depression

University at Buffalo neuroscientists have identified the binding site of low-dose ketamine, providing critical insight into how the medication, often described as a wonder drug, alleviates symptoms of major depression in as little as a few hours with effects lasting for several days.

19 Nov 2024

Study reveals the power of sleep in enhancing motor learning for individuals with brain injury

New research published by scientists at Kessler Foundation provides critical insights into the role of sleep in motor learning for individuals recovering from traumatic brain injury (TBI).

19 Nov 2024

Athletes show better working memory performance than non-athletes

In cognitive science, there has recently been increasing attention to the relationship between sports expertise and working memory.

19 Nov 2024

Adding high-dose IV vitamin C to chemotherapy can boost survival for pancreatic cancer patients

Results from a randomized phase 2 clinical trial show that adding high-dose, intravenous (IV) vitamin C to chemotherapy doubles the overall survival of patients with late-stage metastatic pancreatic cancer from eight months to 16 months.

19 Nov 2024

Small Solutions for Big Problems in Drug Discovery and Delivery

Ijeoma Uchegbu discusses nanomedicine's role in improving medication adherence and developing non-addictive pain relief solutions at ELRIG Drug Discovery 2024.

19 Nov 2024

Stress, diet, and vascular health: Can cocoa flavonols help?

Incorporating flavonol-rich foods may counteract stress-induced vascular impairments, offering a dietary strategy for improved cardiovascular health.

19 Nov 2024

Impact of glucagon-like peptide-1 receptor agonists on alcohol consumption

The impact of GLP-1 RAs on alcohol use is explored, showing potential benefits in reducing intake and cravings, but with mixed results from clinical trials.

19 Nov 2024

Study defines three subtypes of Chiari type-1 malformation to guide treatment

Roughly 4% of the population is affected by a congenital brain malformation that has eluded researchers' efforts to find causes and treatments.

19 Nov 2024

Multiple sclerosis drug could help individuals with reduced working memory

Fampridine is currently used to improve walking ability in multiple sclerosis. A new study shows that it could also help individuals with reduced working memory, as seen in mental health conditions like schizophrenia or depression.

19 Nov 2024

How alcohol impacts male health

This research explores how alcohol consumption disrupts metabolism, damages the liver, and impairs male reproductive health, emphasizing the complex mechanisms and public health implications.

18 Nov 2024

Parkinson's study reveals dopamine's unexpected link to tremor

Researchers from the Champalimaud Foundation shed light on the puzzling relationship between dopamine and rest tremor in Parkinson's disease, finding that preserved dopamine in certain brain regions may actually contribute to tremor symptoms, challenging common beliefs.

18 Nov 2024

Cocoa flavanols can protect the vascular system from stress

New research has found that a flavanol-rich cocoa drink can protect the body's vasculature against stress even after eating high-fat food.

18 Nov 2024

New insights into pain signaling could lead to better chronic pain treatment

When pain signals are passed along the nervous system, proteins called calcium channels play a key role. Researchers at Linköping University, Sweden, have now pinpointed the exact location of a specific calcium channel fine-tuning the strength of pain signals.

18 Nov 2024

Anticoagulants fail to reduce cognitive decline in younger adults with AFib

Prescribing anti-clotting medications to adults younger than age 65 who have atrial fibrillation (AFib) but no other risk factors for stroke did not reduce the risk of cognitive decline, stroke or transient ischemic attack (TIA), according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2024.

18 Nov 2024

SGLT2 inhibitor canagliflozin shown to improve kidney oxygenation in diabetes patients

Type 2 diabetes can lead to diabetic kidney disease, but a class of drugs that cause the kidneys to remove glucose through urine has been gaining attention.

18 Nov 2024

NSAIDs raise bleeding risk in patients taking blood thinners

People who take an anticoagulant medicine double their risk of an internal bleed if they take a type of painkiller called a non-steroidal anti-inflammatory drug (NSAID) such as ibuprofen, diclofenac or naproxen, according to research published in the European Heart Journal [1] today (Monday).

18 Nov 2024

New oral painkiller developed for chronic abdominal pain

University of Queensland researchers have developed a new class of oral painkillers to suppress chronic abdominal pain that is based on the peptide hormone oxytocin that drives childbirth contractions.

18 Nov 2024

Pulses of light show promise in controlling seizures

In what could one day become a new treatment for epilepsy, researchers at UC San Francisco, UC Santa Cruz and UC Berkeley have used pulses of light to prevent seizure-like activity in neurons.

15 Nov 2024

Specific redox protein identified as a critical regulator of ferroptosis

Researchers at Helmholtz Munich, in collaboration with colleagues at Tohoku University, have identified a specific redox protein as a critical regulator of ferroptosis - a form of regulated oxidative cell death.

15 Nov 2024

Vanderbilt receives $3.3 million grant to develop medications for preventing preterm birth

Vanderbilt University Medical Center is receiving $3.3 million over two years through the Advanced Research Projects Agency for Health's (ARPA-H) Sprint for Women's Health for its early-stage research efforts to develop medications designed to suppress premature uterine contractions during pregnancy.

15 Nov 2024