Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Machine learning unlocks blood test secrets for spinal cord injury

Routine blood samples, such as those taken daily at any hospital and tracked over time, could help predict the severity of an injury and even provide insights into mortality after spinal cord damage, according to a recent University of Waterloo study.

23 Sep 2025

Researchers call for consistent biomarker scoring

More than 1500 persons in Norway have had a liver transplantation. But how can doctors know which patients need extra follow-up or additional treatment so that as many as possible can live a long life afterwards?

23 Sep 2025

New framework proposes lactate clearance as key marker for managing cardiogenic shock

A new initiative by The Society for Cardiovascular Angiography & Interventions (SCAI) proposes a new framework and call to action for managing cardiogenic shock (CS), establishing lactate clearance potentially as the standardized, time-based marker of patient trajectory to improve outcomes in one of the deadliest cardiovascular emergencies.

19 Sep 2025

New findings support low-dose ATG to delay progression of type 1 diabetes

New research presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 September) and published simultaneously in The Lancet shows that a much lower dose than previously thought of the old immunomodulatory drug anti-thymocyte globulin (ATG) is safe and effective in preventing progression of type 1 diabetes (T1D) in young people.

19 Sep 2025

AI model maps lifetime disease risks to transform future healthcare planning

Researchers developed Delphi-2M, a transformer-based AI trained on UK Biobank and Danish health data to predict and simulate lifetime trajectories for 1,256 diseases. It accurately forecasted long-term multimorbidity risks, generated synthetic health records, and highlighted comorbidity patterns while exposing key biases.

18 Sep 2025

PANoptosis emerges as a promising strategy against liver cancer

Liver cancer, particularly hepatocellular carcinoma (HCC), remains one of the deadliest cancers, driven by high recurrence and resistance to therapy.

18 Sep 2025

Daily orforglipron GLP-1 pill achieves over 11% weight loss in global obesity trial

In a phase 3 trial, once-daily oral orforglipron induced significant, dose-dependent weight loss over 72 weeks in adults with obesity but no diabetes. It also improved multiple cardiometabolic markers with a safety profile similar to other GLP-1 receptor agonists.

18 Sep 2025

Muscle hormone FGF21 linked to longer survival in ALS

A new research paper was published in Volume 17, Issue 8 of Aging-US on August 9, 2025, titled "The myokine FGF21 associates with enhanced survival in ALS and mitigates stress-induced cytotoxicity."

18 Sep 2025

electronRx to launch pDx app for remote chronic respiratory disease management

electronRx, a leading digital medicine and biomarker company driving healthcare through pulmonary innovation, today announced that it will launch pDx at HLTH 2025.

18 Sep 2025

Mediterranean diet may protect gums by reducing severe periodontitis

This study reveals that the Mediterranean diet may protect against periodontitis, highlighting its benefits for oral health and inflammation reduction.

18 Sep 2025

Younger adults and men with type 2 diabetes face higher risk of sepsis

Living with type 2 diabetes (T2D) may double the risk of developing sepsis-with those aged younger than 60 years and men particularly susceptible, according to a long-term community-based study in Australia, being presented at this year's Annual Meeting of The European Association for the Study of Diabetes (EASD), Vienna (15-19 Sept).

16 Sep 2025

Hair cortisol levels signal mental health risks in children with chronic illness

Long-term stress levels, measured through hair samples, may provide important clues about mental health risks in children with chronic physical illnesses (CPI), according to new research from the University of Waterloo.

15 Sep 2025

Genetic study shows dual GIPR/GLP1R action curbs binge alcohol use

Researchers used drug-target Mendelian randomization to test whether genetically proxied activation of GLP1R and GIPR influences alcohol-related behaviors. They found that GIPR, especially when combined with GLP1R, was linked to lower binge and heavy drinking, healthier food preferences, improved liver markers, and reduced coronary artery disease risk.

15 Sep 2025

UCL launches landmark trial of Alzheimer’s blood test

A major UCL-led clinical trial, aiming to transform the diagnosis of Alzheimer's disease through a simple blood test, is now welcoming its first participants who will be recruited via memory clinics across the UK.

11 Sep 2025

Study identifies C1orf122 as prognostic marker in liver cancer

Primary liver cancer is the third leading cause of cancer-related deaths, of which hepatocellular carcinoma (HCC) accounts for approximately 90% of all liver cancer cases.

11 Sep 2025

Compact bNIRS technology could become a diagnostic toolkit for dementia

Early and accurate diagnosis of dementia remains a major challenge. Standard approaches such as MRI and PET scans can provide valuable information about brain structure and function, but they are expensive, not always accessible, and often too expensive for repeated use.

11 Sep 2025