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Precision probiotics lower blood sugar and cholesterol in mice

Researchers developed a precision probiotic cocktail comprising three Lactobacillus strains that improved glucose control, reduced weight gain, and lowered cholesterol levels in mice fed a high-fat diet. Metabolomic and microbiome analyses revealed host metabolic adaptations and beneficial shifts in gut bacteria, highlighting translational potential for future clinical trials.

28 Sep 2025

Scientists use blood chemistry to predict disease years before it strikes

Researchers built the largest plasma metabolome-phenome atlas using 274,241 UK Biobank participants, linking over 73,000 metabolite-trait and 52,000 metabolite-disease associations. The study shows metabolic risk scores can predict diseases years before diagnosis, with strong accuracy for diabetes and kidney complications.

22 Sep 2025

New class of antihypertensive medications may have both kidney- and cardio-protective benefits

Adding the novel medication baxdrostat to standard care may help manage high blood pressure and delay the progression of kidney disease in people with chronic kidney disease and uncontrolled high blood pressure , according to preliminary research presented at the American Heart Association's Hypertension Scientific Sessions 2025.

8 Sep 2025

Radiometer, Leica Biosystems and Cepheid to come together at IBMS Congress 2025 on Stand 109

Radiometer urgent and acute care testing specialists, will unite with Leica Biosystems and Cepheid to spotlight the breadth and scale of the Danaher Diagnostics portfolio.

5 Sep 2025

Tenofovir amibufenamide shows efficacy in chronic hepatitis B patients with normal ALT

Chronic hepatitis B virus (HBV)-infected patients may exhibit liver fibrosis and other pathological changes despite normal alanine aminotransferase (ALT).

19 Aug 2025

New 2025 guidelines focus on early intervention and lifestyle to manage high blood pressure

Preventing and managing high blood pressure with healthy lifestyle behaviors, such as following a heart-healthy diet including reducing salt intake, staying physically active, maintaining a healthy weight and managing stress—combined with early treatment with medication to lower blood pressure if necessary—are recommended to reduce the risk of heart attack, stroke, heart failure, kidney disease, cognitive decline and dementia, according to a new clinical guideline published today in the American Heart Association's peer-reviewed journals Circulation and Hypertension, and in JACC, the flagship journal of the American College of Cardiology.

14 Aug 2025

Study identifies biomarkers that could help predict and manage chronic kidney disease

Biomarkers that could help predict and manage chronic kidney disease (CKD) have been identified in a new study led by the University of Surrey.

12 Aug 2025

Vital role of physical activity in early type 2 diabetes care

New research to be presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 September) shows, among people recently diagnosed with type with type 2 diabetes and no previous cardiovascular disease, a clear association exists between a person's self-reported physical activity and their risk of all-cause mortality and major adverse cardiac events (MACE), that include heart attacks and strokes.

8 Aug 2025

Magnesium deficiency drives higher mortality in hyperlipidemia

MgDS serves as a potential biomarker for mortality risk in hyperlipidemic adults, emphasizing the need for targeted approaches to manage cardiovascular health.

6 Aug 2025

New blood markers predict kidney disease and mortality in diabetes

Kidney complications in diabetes often progress silently, putting patients at risk of life-threatening outcomes long before any symptoms appear. Identifying individuals with diabetes who are at risk of rapid kidney function decline or early death has challenged doctors for decades, with traditional markers like serum creatinine and urinary albumin falling short of accurately predicting these risks.

29 Jul 2025

Boosting gut-friendly foods may slow biological aging, large US study finds

Higher scores on a dietary index linked to gut microbiota health are associated with slower biological aging in US adults, according to a large cross-sectional NHANES study. The findings suggest that improving diet quality for gut microbial diversity may help reduce age-related disease risk.

20 Jul 2025

New study identifies factors linked to successful weight loss using GLP-1RAs

A study in Diabetes, Obesity and Metabolism has identified certain characteristics that might influence people's weight loss after taking prescription drugs called glucagon-like peptide-1 receptor agonists (GLP-1RAs), such as semaglutide (sold under the brand names Ozempic and Wegovy).

9 Jul 2025

Assisted reproductive technology raises pregnancy risks in women with kidney transplants

Women with kidney transplants who use assisted reproductive technology (ART) to conceive might face higher risks of complications during pregnancy, according to new research from the University of Cincinnati College of Medicine.

7 Jul 2025

Can salt substitutes lower blood pressure in diabetes? A new Cochrane review aims to find out

Researchers will systematically review whether replacing regular sodium salt with alternatives like potassium or magnesium salts helps lower blood pressure in adults with diabetes. The protocol outlines a rigorous plan to evaluate blood pressure effects, safety, and adherence using data from RCTs and quasi-RCTs.

18 Jun 2025

Popular painkiller use linked to gut microbiome shifts

New insights into gout management strategies and cardiovascular outcomes

The European Alliance of Associations for Rheumatology - recommends that serum urate should be maintained at <6 mg/dL (360 µmol/L) and <5 mg/dL (300 µmol/L) in those with severe gout.

15 Jun 2025

Vaccination linked to better kidney outcomes in hospitalized COVID-19 patients

Vaccinated patients hospitalized with COVID-19 who developed acute kidney injury had better outcomes than unvaccinated patients with the same condition, new research suggests.

14 Jun 2025

Nanoplastics reshape gut microbiome, weakening gut defenses

Polystyrene nanoplastics impact gut health by modifying microbiota interactions via extracellular vesicles, raising concerns about environmental nanoplastics.

12 Jun 2025

Study: Deceased-donor kidney transplants do not benefit all patients equally

A major international study, being presented today at the 62nd ERA Congress, reveals that the long-accepted survival advantage of deceased-donor kidney transplantation does not extend equally to every patient and every donor organ.

5 Jun 2025

Nicotinamide riboside shows promise in treating Werner syndrome symptoms

Werner syndrome (WS) is a rare genetic disorder that causes premature aging and serious complications. In the first clinical trial of its kind, researchers from Japan with the company Niagen Bioscience, investigated the effects of nicotinamide riboside (NR), a vitamin B3 derivative, in patients with WS.

5 Jun 2025