Metabolic Disorders News and Research

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$Bone fractures often go unrecognized as early signs of osteoporosis$

Bone fractures often go unrecognized as early signs of osteoporosis

Many fractures are early-warning signs of osteoporosis. Yet in everyday clinical care they often go unrecognized and undocumented as warning signs, according to a new nationwide Austrian study by the Complexity Science Hub (CSH) and the Ludwig Boltzmann Institute for Osteology (LBI Osteology). Men are affected more often.

20 Jul 2026

Evening chronotype links later eating with higher body fat

Research shows evening chronotypes in women consume more energy later, leading to higher body fat and metabolic issues, highlighting chrono-nutrition's role.

16 Jul 2026

Insilico and Bora Pharmaceuticals forge strategic AI-driven drug discovery alliance

Insilico Medicine, a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, today announced a multi-target strategic alliance with Bora Pharmaceuticals Co., Ltd., a global leader in pharmaceutical manufacturing.

14 Jul 2026

New consensus provides updated guidance for managing prolactinoma tumors

Prolactinomas are the most common functional pituitary neuroendocrine tumors, accounting for nearly half of all hormone-secreting pituitary adenomas.

13 Jul 2026

Study reveals distinct roles of oxygen-sensing proteins in skeletal muscles

Skeletal muscles-responsible for movement, joint stabilization, and postural support-are highly metabolically active and heavily reliant on oxygen during physical activity.

13 Jul 2026

Harvard University hosts the world's largest conference dedicated to longevity biotechnology

The 13th Aging Research & Drug Discovery (ARDD) Meeting, the world's largest conference dedicated to longevity biotechnology, will take place from October 1-3, 2026, at the David Rubenstein Treehouse at Harvard University.

11 Jul 2026

Insilico Medicine founder to highlight sustainable longevity at BIO Asia-Taiwan

Dr. Alex Zhavoronkov, Founder and CEO of Insilico Medicine, has been invited to attend BIO Asia-Taiwan, which will be held from July 15 to 19 in Taiwan, China.

11 Jul 2026

Early menopause remains common among women in low and middle income countries

Early menopause affects 1 in 14 women aged 30 to 49 living in low and middle income countries, finds a pooled data analysis of its prevalence in 44 nations published in the open access journal BMJ Global Health.

7 Jul 2026

Updated ABCs framework gives clinicians a clearer path to prevent heart disease

A 2026 State-of-the-Art review updates the ABCs of cardiovascular disease prevention to help clinicians apply contemporary risk assessment, lifestyle, pharmacologic, and cardiometabolic strategies in routine care. The framework emphasizes PREVENT™ risk equations, Life’s Essential 8, CKM syndrome, obesity care, lipid lowering, blood pressure control, healthy aging, heart failure prevention, and atrial fibrillation management.

7 Jul 2026

Insilico Medicine highlights AI drug discovery progress at executive summit

Dr. Alex Aliper, Co-founder and President of Insilico Medicine, will attend the AI for Good Global Summit 2026 in Geneva, Switzerland, on July 7.

3 Jul 2026

Study reveals double burden of malnutrition among low-income urban children in India

Children growing up in a low-income urban community in Vellore are now facing two seemingly opposite forms of malnutrition simultaneously: persistent thinness and rising obesity by the time they reach primary school age.

2 Jul 2026

Insilico Medicine partners with Takeda for AI-driven drug discovery

Insilico Medicine, a leader in clinical-stage generative AI for drug discovery, today announced a strategic collaboration agreement with Takeda to use its proprietary end-to-end platform, Pharma.AI, to advance drug candidates across the company's therapeutic areas.

2 Jul 2026

Fatty liver disease fuels aggressive metastatic colorectal cancer spread

Researchers at VIB and KU Leuven, with international partners, have uncovered how fatty liver disease can fuel the most aggressive form of metastatic colorectal cancer.

1 Jul 2026

WHO urges countries to expand newborn screening for birth defects

The World Health Organization (WHO) today calls on countries to expand newborn screening for birth defects, highlighting how early detection and treatment can save lives and reduce lifelong disability for millions of children.

24 Jun 2026

Insilico and SK Biopharmaceuticals partner to develop AI-driven neuroimmune therapies

Insilico Medicine, a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, and SK Biopharmaceuticals, a Korean-based company leads the way in biotech innovation with groundbreaking drug research, development, and commercialization worldwide, announced a research and development collaboration at the BIO 2026 International Convention to discover AI-enabled innovative drug candidates in the neuroimmune area of the central nervous system.

22 Jun 2026

Gut microbes may help explain why obesity and type 2 diabetes become harder to reverse

This review describes how gut microbial messengers, including SCFAs, microbiota-modified bile acids, neuroactive metabolites, and extracellular vesicles, may shape obesity and type 2 diabetes through the microbiota-gut-brain axis.

17 Jun 2026

AI-designed drug for Parkinson's begins first human trial

Insilico Medicine ("Insilico", HKEX: 3696), a clinical-stage biotechnology company powered by generative artificial intelligence (AI), today announced it has achieved the first clinical milestone in its co-development collaboration with Hygtia Therapeutics with the completion of first-in-human dosing in the Phase I study of ISM8969.

17 Jun 2026

Researchers map rare DHDDS disease mechanism using lab-grown mini brains

Variants in the DHDDS gene cause a severe neurodegenerative condition, characterized by tremors, seizures, coordination and learning difficulties, usually manifesting in early childhood. This Parkinson's-like condition is extremely rare, and until recently, parents were told that there was nothing that could be done to slow down its progression.

15 Jun 2026

Eliminating dietary sugar may disrupt gut health and promote inflammation

Eliminating sugar from your diet may be more detrimental than previously thought, according to an animal study being presented Saturday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

14 Jun 2026

Western diet weakens the gut’s nervous system through iron-dependent damage

A JCI study found that exposure to a Western diet in mice and to palmitic acid in murine and ex vivo human enteric nervous system models triggered ferroptosis, characterized by iron loading, lipid peroxidation, mitochondrial stress, and enteric neuronal loss. Boosting Nrf2 signaling protected enteric neurons and prevented Western diet-induced delayed colonic transit in mice, pointing to a potential pathway linking dietary fat exposure to gut motility dysfunction.

10 Jun 2026