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Researchers develop novel exosome-based therapeutic agent for treating traumatic CNS injuries

Traumatic injuries of the central nervous system (CNS)-such as traumatic brain injury (TBI) and traumatic spinal cord injury (SCI)-are characterized by oxidative damage and neuroinflammation.

28 Aug 2025

Probiotic enhances cholesterol drug efficacy but raises safety concerns at high doses

A recent study published in Engineering has shed light on the complex interactions between probiotics and drugs, particularly focusing on the effects of the probiotic Lacticaseibacillus paracasei Zhang (LCZ) on the cholesterol-lowering drug lovastatin.

28 Aug 2025

Most alternative treatments for autism lack reliable evidence

The most comprehensive quantitative review of research into complementary and alternative treatments for autism has found no strong evidence to support their use, and that the safety of these treatments was rarely assessed.

28 Aug 2025

Longitudinal study reveals how GLP-2 analog therapy transforms the intestinal environment

Researchers from Japan discover that glucagon-like peptide-2 (GLP-2) analogs can deeply and beneficially reshape the intestinal environment.

27 Aug 2025

Online cognitive behavioral therapy shows promise for treating bulimia nervosa

Bulimia nervosa (BN), or bulimia, is a mental health disorder characterized by binge eating and a fear of gaining weight, which drives people to try and avoid weight gain, usually by compensatory (vomiting etc.).

27 Aug 2025

New trial will test if a low-plastic lifestyle improves your health

A new protocol published in BMJ Open outlines the PERTH trial, a randomized controlled study testing whether a four-week low-plastic lifestyle can reduce exposure to plastic-derived endocrine-disrupting chemicals.

27 Aug 2025

Transcutaneous vagal nerve stimulation shows promise for gastrointestinal disorders

Imbalanced autonomic function, characterized by reduced vagal activity and sympathetic dominance, is increasingly recognized in various gastrointestinal (GI) disorders.

27 Aug 2025

Qureight's AI 3D imaging platform to support Calluna Pharma's Phase 2 AURORA study of CAL101 in idiopathic pulmonary fibrosis (IPF)

Qureight, a techbio company advancing the understanding of lung and heart disease through application of its AI-powered imaging and clinical data curation platform, today announced that it has been selected by Calluna Pharma to support its Phase 2 AURORA study.

27 Aug 2025

New class of insecticide offers yearlong protection against mosquito-borne diseases

A relatively new class of insecticide that can be disseminated on something the size of a sheet of paper offers protection for up to a year against mosquitoes that spread malaria, as well as dengue, West Nile, yellow fever, and Zika, UC San Francisco researchers have found.

26 Aug 2025

Genetic variants mimicking IL-6 inhibition linked to lower cardiovascular risk

People with lower interleukin-6 activity have a reduced risk of cardiovascular diseases, a new LMU study reveals.

26 Aug 2025

Novel monoclonal antibodies show promise in preventing severe mpox disease

A team from the Microbiology Department at the Icahn School of Medicine at Mount Sinai has discovered three powerful monoclonal antibodies from a person who had previously been infected with mpox (formerly known as monkeypox).

26 Aug 2025

Research uncovers key role of the brain's blood flow dynamics in Alzheimer’s disease

Over seven million Americans are living with Alzheimer's disease (AD) and the heartbreaking day-to-day battle with the effects of cognitive decline.

25 Aug 2025

Strategic tips for early-stage animal health companies facing regulatory challenges

Karen Greenwood shares practical advice for early-stage animal health companies navigating FDA CVM processes.

From DSI, a PLG Company 25 Aug 2025

How a single gene reshapes pain perception through polyamine signaling

Researchers have identified SLC45A4 as a neuronal polyamine transporter genetically linked to human chronic pain. Loss of this gene in mice disrupts polyamine balance, alters spinal GABA levels, and reduces heat and tonic pain sensitivity.

24 Aug 2025

SOX2 drives progression and therapy resistance in advanced prostate cancer

Prostate cancer remains a global health challenge, ranking as the second most common malignancy among men.

22 Aug 2025

CHI3L1 emerges as a powerful biomarker for liver disease diagnosis and management

The identification of Chitinase-3-like protein 1 (CHI3L1) as a crucial biomarker in liver disease is revolutionizing how clinicians approach the diagnosis, monitoring, and treatment of various liver conditions.

22 Aug 2025

Natural products offer promising solutions in prosthodontics and oral implantology

Infection control is paramount in prosthodontics and oral implantology to prevent complications like denture stomatitis and peri-implantitis.

22 Aug 2025

Evidence review questions ketamine’s role in chronic pain treatment

A Cochrane review assessed ketamine and other NMDA receptor antagonists for chronic non-cancer pain. The evidence was low to very low certainty, showing no clear pain relief and potential adverse effects with intravenous ketamine.

21 Aug 2025

Can AI help you eat healthier?

Researchers developed and validated an AI-based nutrition recommendation system (AINR) that generates weekly Mediterranean meal plans tailored to individual needs and dietary restrictions. Tested on 4,000 simulated users, the system achieved high accuracy in calorie and nutrient targets but struggled with profiles involving milk and nut allergies.

21 Aug 2025

COVID-19 vaccine successes boosted hesitancy - can trust and equity restore immunization?

Researchers show that countries with higher initial COVID-19 vaccine acceptance also achieved stronger booster uptake, but trust and access remain decisive. The commentary warns that vaccine successes also fueled hesitancy, demanding structural reforms, clear communication, and proactive strategies to protect immunization.

21 Aug 2025

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Efficacy News and Research

Researchers develop novel exosome-based therapeutic agent for treating traumatic CNS injuries

Probiotic enhances cholesterol drug efficacy but raises safety concerns at high doses

Most alternative treatments for autism lack reliable evidence

Longitudinal study reveals how GLP-2 analog therapy transforms the intestinal environment

Online cognitive behavioral therapy shows promise for treating bulimia nervosa

New trial will test if a low-plastic lifestyle improves your health

Transcutaneous vagal nerve stimulation shows promise for gastrointestinal disorders

Qureight's AI 3D imaging platform to support Calluna Pharma's Phase 2 AURORA study of CAL101 in idiopathic pulmonary fibrosis (IPF)

New class of insecticide offers yearlong protection against mosquito-borne diseases

Genetic variants mimicking IL-6 inhibition linked to lower cardiovascular risk

Novel monoclonal antibodies show promise in preventing severe mpox disease

Research uncovers key role of the brain's blood flow dynamics in Alzheimer’s disease

Strategic tips for early-stage animal health companies facing regulatory challenges

How a single gene reshapes pain perception through polyamine signaling

SOX2 drives progression and therapy resistance in advanced prostate cancer

CHI3L1 emerges as a powerful biomarker for liver disease diagnosis and management

Natural products offer promising solutions in prosthodontics and oral implantology

Evidence review questions ketamine’s role in chronic pain treatment

Can AI help you eat healthier?

COVID-19 vaccine successes boosted hesitancy - can trust and equity restore immunization?

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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