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Gut bacteria patterns help predict insulin resistance in type 2 diabetes, study finds

Researchers used 16S rRNA sequencing and machine learning to identify gut microbiome patterns associated with insulin resistance severity in people with type 2 diabetes. XGBoost models showed that specific bacterial genera, including Bacteroides and Faecalibacterium, help distinguish individuals with higher insulin resistance from healthy controls.

19 Feb 2026

Intermittent calorie restriction proves as effective as daily calorie cuts for type 2 diabetes

A post-hoc analysis of two clinical trials compared continuous calorie restriction with early time-restricted eating in adults with type 2 diabetes and overweight or obesity over three months. Both approaches improved weight, body composition, and metabolic health, with no clear superiority except for lower dropout with intermittent restriction.

18 Feb 2026

Undiagnosed diabetes and kidney disease raise heart risk

Diabetes and kidney disease are major risk factors for heart disease, yet many cases are undiagnosed. In addition, a consumer survey done last fall suggests that most people don't realize that their heart, kidney and metabolic health (how the body creates, uses and stores energy) are connected.

18 Feb 2026

Does intermittent fasting help you lose more weight? Evidence review finds no clear advantage

A Cochrane systematic review of 22 randomized trials involving 1,995 adults with overweight or obesity found intermittent fasting produces weight loss comparable to traditional calorie restriction. Evidence suggests little additional benefit for quality of life or adverse effects, with overall certainty ranging from low to moderate and long-term effects still unclear.

17 Feb 2026

Study links microbe-rich diets with better insulin and cholesterol markers

This exploratory Australian study developed a database to estimate live microbe content in foods and examined associations with cardiometabolic health indicators in adults. Higher intake of foods estimated to contain live microbes was linked with favourable markers such as higher HDL cholesterol and lower BMI, insulin, and waist circumference, although causality cannot be inferred.

16 Feb 2026

Intermittent fasting does not seem to work for overweight or obese adults

Intermittent fasting is unlikely to lead to greater weight loss in overweight or obese adults than traditional dietary advice or doing nothing, a new Cochrane review finds.

16 Feb 2026

Big breakfast study reveals protein curbs appetite but fiber delivers stronger gut microbiome benefits

A randomized crossover weight loss trial in adults with overweight or obesity found that higher protein big breakfasts improved satiety, while higher fibre breakfasts produced slightly greater weight loss and more favourable gut microbiota markers. Both diets improved metabolic biomarkers, but microbiota changes reflected surrogate gut health indicators rather than direct clinical outcomes.

15 Feb 2026

Higher red meat intake links to greater diabetes odds in large US study

Higher intakes of total, processed, and unprocessed red meat were associated with greater odds of diabetes in a nationally representative sample of US adults. Statistical substitution models suggest replacing red meat with plant proteins, poultry, dairy, or whole grains may be linked to lower diabetes odds, though causality cannot be inferred.

15 Feb 2026

Diabetic nephropathy shows severe biochemical abnormalities

Chronic diabetes mellitus is marked by hyperglycemia and metabolic dysfunction, increasing the risk of complications such as nephropathy.

13 Feb 2026

Magnesium lower fasting blood sugar in older adults

Magnesium boosts fasting glucose control in older adults with deficiency, but preventing diabetes progression may need more than just mineral correction.

13 Feb 2026

Aligning overnight fasting with sleep improves heart health

A new Northwestern Medicine study has personalized overnight fasting by aligning it with individuals' circadian sleep-wake rhythm - an important regulator of cardiovascular and metabolic function - without changing their caloric intake.

12 Feb 2026

South Asian adults in the U.S. have higher prevalence of risk factors for heart disease

South Asian adults in the U.S. report doing many of the right things for heart health, yet they show significantly higher rates of prediabetes, diabetes and hypertension than white and Chinese adults, and higher than or roughly similar rates to Black and Hispanic patients, according to a new study led by Northwestern Medicine.

11 Feb 2026

Study reveals DNA methylation score that better detects alcohol intake than standard biomarkers

A Mediterranean cohort study evaluated a DNA methylation biomarker of alcohol intake and compared it with conventional indicators such as GGT. The epigenomic score correlated with alcohol exposure, linked to telomere shortening and epigenetic aging markers, but findings remain observational and population-specific.

9 Feb 2026

Tirzepatide shows dual benefits in sleep apnea trial improving metabolism and reducing inflammation

Tirzepatide significantly improved cardiometabolic risk markers in adults with obesity and moderate to severe obstructive sleep apnea in the SURMOUNT-OSA phase 3 trials. Mediation analyses suggest both weight loss and reduced sleep-disordered breathing contributed to improvements in inflammation, insulin resistance, lipids, and blood pressure.

9 Feb 2026

Time-restricted feeding reduces disease activity and inflammation in Crohn's patients

A new randomized controlled study funded by the Crohn's & Colitis Foundation found that time-restricted feeding-a form of intermittent fasting-significantly reduced symptomatic disease activity and systematic inflammation in adults with Crohn's disease and overweight or obesity.

9 Feb 2026

Unprocessed beef does not worsen metabolic health in prediabetes

Short-term unprocessed beef intake shows no adverse effects on glucose regulation or metabolic health compared to poultry in individuals with prediabetes.

2 Feb 2026

Eating melatonin-rich foods is linked to lower obesity and depression rates

This cross-sectional analysis of 8,320 Brazilian adults quantified melatonin intake from habitual diets and examined associations with multiple chronic health outcomes. Higher dietary melatonin intake was inversely associated with obesity and depression in a non-linear pattern, with no significant associations observed for other conditions.

28 Jan 2026

New trial tests strategies to protect heart health during prostate cancer therapy

City of Hope, one of the largest and most advanced cancer research and treatment organizations in the United States with its National Medical Center ranked among the nation's top cancer centers by U.S. News & World Report, has opened a phase 2 clinical trial comparing three different strategies for protecting heart health in prostate cancer patients who receive androgen deprivation therapy (ADT), a potentially lifesaving hormone therapy.

26 Jan 2026

Three daily servings of full-fat dairy do not worsen weight or blood markers

This randomized 12-week trial examined whether adding three daily servings of full-fat dairy to diets aligned with Canada’s Food Guide affects body weight, cardiometabolic markers, and nutrient intake in adults with overweight or obesity. Full-fat dairy intake did not adversely affect weight, body composition, or metabolic health and increased calcium and protein intake, supporting dietary compatibility rather than therapeutic benefit.

26 Jan 2026

When you eat matters: early time-restricted eating improves metabolic health

Time-restricted eating improves several metabolic outcomes compared with usual diets, with benefits observed for body weight, adiposity, blood pressure, insulin, glucose, and triglycerides. Early eating windows consistently outperform late eating, while the optimal duration of food intake remains uncertain.

22 Jan 2026

Fasting News and Research

Gut bacteria patterns help predict insulin resistance in type 2 diabetes, study finds

Intermittent calorie restriction proves as effective as daily calorie cuts for type 2 diabetes

Undiagnosed diabetes and kidney disease raise heart risk

Does intermittent fasting help you lose more weight? Evidence review finds no clear advantage

Study links microbe-rich diets with better insulin and cholesterol markers

Intermittent fasting does not seem to work for overweight or obese adults

Big breakfast study reveals protein curbs appetite but fiber delivers stronger gut microbiome benefits

Higher red meat intake links to greater diabetes odds in large US study

Diabetic nephropathy shows severe biochemical abnormalities

Magnesium lower fasting blood sugar in older adults

Aligning overnight fasting with sleep improves heart health

South Asian adults in the U.S. have higher prevalence of risk factors for heart disease

Study reveals DNA methylation score that better detects alcohol intake than standard biomarkers

Tirzepatide shows dual benefits in sleep apnea trial improving metabolism and reducing inflammation

Time-restricted feeding reduces disease activity and inflammation in Crohn's patients

Unprocessed beef does not worsen metabolic health in prediabetes

Eating melatonin-rich foods is linked to lower obesity and depression rates

New trial tests strategies to protect heart health during prostate cancer therapy

Three daily servings of full-fat dairy do not worsen weight or blood markers

When you eat matters: early time-restricted eating improves metabolic health

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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