Organoids News and Research

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Organoids are three-dimensional cell cultures from embryonic stem cells or induced pluripotent stem cells that model important features of whole organs.

Engineered vessels boost retinal organoid function, enabling advanced disease modeling

Until now, it has been difficult to maintain retinal ganglion cells deep inside organoids over extended periods. The supply of nutrients and oxygen in the densely packed tissues is limited, leading to cell death.

14 Jan 2026

Magnetic torque boosts cardiac organoid maturation, mimicking heart development

Heart disease remains the leading cause of death worldwide, yet progress in understanding and treating cardiac disorders is limited by the shortcomings of existing experimental models.

13 Jan 2026

SPINECRAFT: Engineering a 4D human spinal cord for disease research

Zaida Álvarez Pinto, Principal Investigator at the Institute for Bioengineering of Catalonia (IBEC), has been awarded an ERC Consolidator Grant, one of the most prestigious and competitive sources of funding in the European Union.

9 Jan 2026

Pancreatic organoid study reveals key factors shaping complex lumen formation

Organs often have fluid-filled spaces called lumens, which are crucial for organ function and serve as transport and delivery networks.

9 Jan 2026

Novel antisense oligonucleotide shows promise against aggressive pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is the most lethal form of pancreas cancer. It's also the most common form of the disease.

8 Jan 2026

Pitavastatin shows pomise in overcoming chemotherapy resistance in triple-negative breast cancer

Triple-negative breast cancer (TNBC) is among the most aggressive types of breast cancer, lacking estrogen, progesterone, and HER2 receptors and thus relying primarily on cytotoxic chemotherapy.

7 Jan 2026

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

In our latest interview, News-Medical speaks with Rosanna Zhang from ACROBiosystems about utilizing organoids for disease modeling in the field of neuroscience research.

From ACROBiosystems 6 Jan 2026

Novel method can generate functional organoids from human adult adipose tissue

A recent study published in Engineering has unveiled a novel approach to generating functional organoids from human adult adipose tissue.

30 Dec 2025

New grant supports research into drug-induced brain toxicity

Important FDA-approved drugs to treat HIV and cancer can save lives, but they come with their own risks. Some drugs used clinically are known to cause neurological side effects in up to half of patients, ranging from confusion and memory problems to permanent nerve damage.

19 Dec 2025

New tear gland organoids shed light on the biology of dry eye disease

An estimated 5-15% of people have problems with dry eyes, with symptoms including eye redness, stinging, or burning sensation, and eye fatigue. Dry eye disease (DED) occurs when the eyes' tear glands produce insufficient or poor-quality tears which can be due to allergy or autoimmune disease, hormonal changes, aging, etc.

18 Dec 2025

MEA-driven graph modeling identifies early connectivity changes linked to autism

Multi-electrode arrays (MEAs) provide a noninvasive interface with sub-millisecond temporal resolution and long-term, multi-site recordings, enabling mechanistic investigations of in vitro human brain development and disease-related dysfunction; nevertheless, conventional MEA pipelines largely rely on firing/burst statistics or channel-/waveform-level features, which can be insufficient to systematically characterize and interpret network-level organization and its subtle pathological deviations.

16 Dec 2025

Atelerix enters agreement with Cherry Biotech to integrate non-cryogenic transport solutions with advanced organoid models

Atelerix, a biotech company revolutionizing cell preservation and biological transport with its pioneering hydrogel encapsulation technology, today announced it has entered a partnership with Cherry Biotech, a French company specializing in organ-on-chip and organoid technologies for biomedical research.

15 Dec 2025

Human heart organoids enable new therapies for atrial fibrillation

Though an estimated 60 million people around the world have atrial fibrillation, or A-fib, a type of irregular and often fast heartbeat, it's been at least 30 years since any new treatments have been developed.

12 Dec 2025

New findings show why the human intestine uniquely presents gluten to T cells

Human intestinal M cells function as dendritic cell-like antigen-presenting cells, displaying constitutive MHC-II activity and specialized machinery for processing gluten. Their ability to deamidate and present gliadin peptides positions them as key initiators of immune responses relevant to coeliac disease.

11 Dec 2025

Study reveals how Ebola and Marburg viruses damage the human gut

Ebola (EBOV) and Marburg virus (MARV) are highly lethal viruses that cause severe disease in infected patients by extensively damaging the body.

11 Dec 2025

Discovery links human M cells to early steps of celiac disease

The human small intestine absorbs nutrients while protecting us from potentially harmful microbes. One of the cell types that plays a key role in this protection is the microfold cell, or M cell.

10 Dec 2025

Study provides first molecular evidence that ferroptosis can drive neurodegeneration

Researchers at Helmholtz Munich, the Technical University of Munich and the LMU University Hospital Munich uncovered a mechanism that protects nerve cells from premature cell death, known as ferroptosis.

4 Dec 2025

Bacterial enzyme linked to heart complications in pneumonia

Pneumonia is a disease that burdens the healthcare system with more that 1.2 million emergency room visits each year and more than 41,000 adult deaths in the United States.

4 Dec 2025

Retinal organoids provide a powerful tool to diagnose and study Leber congenital amaurosis

Leber Congenital Amaurosis (LCA) is an inherited retinal disease leading to severe vision impairment from early infancy, affecting 2-3 out of every 100,000 newborns. LCA is caused by variants in certain genes from which proteins essential for retinal cell function and survival are made.

3 Dec 2025

Automated production of lung organoids could revolutionize the development of treatments

A team of scientists have developed a simple method for automated manufacturing of lung organoids which could revolutionize the development of treatments for lung disease.

1 Dec 2025

Organoids News and Research

Further Reading

Engineered vessels boost retinal organoid function, enabling advanced disease modeling

Magnetic torque boosts cardiac organoid maturation, mimicking heart development

SPINECRAFT: Engineering a 4D human spinal cord for disease research

Pancreatic organoid study reveals key factors shaping complex lumen formation

Novel antisense oligonucleotide shows promise against aggressive pancreatic cancer

Pitavastatin shows pomise in overcoming chemotherapy resistance in triple-negative breast cancer

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

Novel method can generate functional organoids from human adult adipose tissue

New grant supports research into drug-induced brain toxicity

New tear gland organoids shed light on the biology of dry eye disease

MEA-driven graph modeling identifies early connectivity changes linked to autism

Atelerix enters agreement with Cherry Biotech to integrate non-cryogenic transport solutions with advanced organoid models

Human heart organoids enable new therapies for atrial fibrillation

New findings show why the human intestine uniquely presents gluten to T cells

Study reveals how Ebola and Marburg viruses damage the human gut

Discovery links human M cells to early steps of celiac disease

Study provides first molecular evidence that ferroptosis can drive neurodegeneration

Bacterial enzyme linked to heart complications in pneumonia

Retinal organoids provide a powerful tool to diagnose and study Leber congenital amaurosis

Automated production of lung organoids could revolutionize the development of treatments

New Approach Methodologies, the 3Rs and Multimodal Imaging in Preclinical Research - eBook eBook

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Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

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