Chromatography News and Research

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Chromatography in Greek means to ‘write with colors.’ It is a versatile separation technique developed in 1903 by Mikhail Tswett, a Russian botanist. He separated colorful plant pigments using a column of calcium carbonate. Ever since its discovery, chromatography has evolved as a powerful tool in the lab for the separation and identification of different compounds in a mixture.

Could the type of fiber children eat matter for their developing gut microbiome?

A recent study found that different dietary fibers can shape the composition and activity of the gut microbiome during early childhood, with xyloglucan, arabinoxylan, and pectin increasing short-chain fatty acid production in laboratory fermentation experiments. Some fibers also supported gut barrier measures and altered inflammatory responses, while observational data linked higher pectin intake with greater microbial diversity in young children.

31 Aug 2026

New framework standardizes selenosugar research and selenium metabolism studies

Selenosugars are the major urinary metabolites responsible for the physiological excretion of selenium. Understanding selenium metabolism relies on accurately detecting and identifying selenosugars.

20 Aug 2026

Early-life stress rewires brain epigenetics to heighten sensitivity to future stress

. Early-life stress increased SETD7 and H3K4me1 in the ventral tegmental area of mice, creating an epigenetically primed state that heightened later transcriptional, neuronal, and behavioral responses to stress. Reducing Setd7 during development lowered H3K4me1 and weakened these stress-sensitizing effects, identifying a mechanism that may help explain how early adversity leaves lasting biological effects.

11 Aug 2026

Voltammetry and machine learning for real-time neurotransmitter detection

Anne Andrews (UCLA) explains how voltammetry and machine learning can track multiple neurotransmitters in real time, even with overlapping signals.

From Pittcon 10 Aug 2026

Blood filtration method helps clear circulating lipids and toxic microplastics

The machine is not new. Some version of it has run in hospital treatment rooms for about four decades, drawing blood from one arm, separating out the plasma, passing it across a filter or an adsorber, and returning it to the other arm.

4 Aug 2026

A common dietary nutrient feeds a gut pathway linked to atrial fibrillation

Researchers linked higher plasma TMAO to prevalent atrial fibrillation in 5,090 people and found that TMAO or choline supplementation accelerated AF onset, progression, atrial remodeling, and electrical dysfunction in mice. Inhibiting gut microbial TMA production lowered circulating TMAO and delayed AF in mice, identifying a potential therapeutic pathway that now requires human testing.

27 Jul 2026

Spermidine boosts key cellular processes linked to aging in early research

This review finds that spermidine supports autophagy, mitochondrial function, and healthspan in experimental models, while observational studies link higher dietary intake to lower mortality. However, human trials have produced limited and mixed results, leaving its clinical role in healthy aging unresolved.

23 Jul 2026

Stuffed toys can release short-chain PFAS into saliva, study finds

Researchers tested 18 stuffed toys and found that all released at least one targeted PFAS into artificial saliva under mouthing-relevant conditions, with PFHxA driving much of the variation between products. Modeled intake of the four PFAS covered by EFSA’s group tolerable weekly intake remained below that benchmark, but some high-PFHxA toys had reduced margins of exposure, and water rinsing produced mixed results.

22 Jul 2026

Building the next generation of DMTA for future-ready drug discovery

Discover how the next generation of DMTA is creating a future-ready drug discovery engine through AI and automation.

From TTP plc 15 Jul 2026

How to overcome purification bottlenecks in modern drug discovery

Learn how to overcome purification bottlenecks in modern drug discovery with advanced purification strategies, streamlined workflows, and automation.

From TTP plc 15 Jul 2026

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

Frances Arnold on directed enzyme evolution: random mutation plus smart screening, and why it changed enzyme engineering and industry.

From Pittcon 14 Jul 2026

Novogene Europe launches Untargeted Metabolomics Service at Cambridge Omics Centre

Novogene Europe, a multiomics research services partner, today announced that it has strengthened its position as a multiomics partner with the launch of its Untargeted Metabolomics Service through its Cambridge Omics Centre.

From Novogene Europe 13 Jul 2026

Cold-exposed mothers pass metabolic protection to male rat offspring through milk

Maternal cold exposure during early pregnancy improved glucose control and reduced liver fat in male rat offspring, with benefits persisting into late adulthood. The findings implicate a breast milk LCA, gut microbiota, and Th17 immune pathway, while human cohort data showed an observational link between winter conception and lower MASLD risk.

12 Jul 2026

Direct-to-definitive toxicology screening: Moving beyond immunoassays in clinical toxicology

Discover expert insights into toxicology screening with mass spectrometry, reducing false results and improving patient safety in clinical toxicology.

From Waters Advanced Diagnostics 9 Jul 2026

Smoking shows no major impact on the eye microbiome in small study

A small study found no evidence that smoking causes large or consistent shifts in the ocular surface microbiome or tear proteome. The authors caution that subtle smoking-related effects cannot be ruled out, given the small cohort and the ocular surface's low-biomass, contamination-sensitive microbial niche.

8 Jul 2026

Eppendorf focuses outreach programs to advance STEM education in Europe

Eppendorf, a leading international life science company that develops, manufactures, and distributes instruments, consumables, and services for use in laboratories around the world, today highlights its European outreach activities dedicated to addressing persistent challenges in STEM education.

From Eppendorf 7 Jul 2026

Botanical prebiotics may steer skin microbes toward healthier balance

Researchers tested plant-derived prebiotic candidates against selected skin-associated bacteria and found that garlic, flaxseed, and mango ginger extracts inhibited S. aureus or acne-associated C. acnes in vitro. Onion and guduchi extracts modestly promoted S. epidermidis, suggesting a microbiome-targeted skincare route that now needs validation in skin models and human studies.

30 Jun 2026

Trial identifies 4 grams a day as the tested safe level for L-tyrosine in healthy men

A randomized, crossover trial in healthy adult men found that 4 weeks of L-tyrosine supplementation at doses up to 4 g/day did not cause clinically meaningful changes in safety markers, diet, blood pressure, or body measures. The highest tested dose, 4 g/day, was identified as the no-observed-adverse-effect level under the study’s four-week conditions, although broader and longer-term studies are still needed.

23 Jun 2026

Optimized proximity labeling platform tracks cellular protein communication networks

The body's organs are in constant communication. Fat tissue tells the liver when to store or release energy, the immune system signals localized inflammation, and thousands of proteins carry these messages to organs throughout the body.

22 Jun 2026

PMOS rethink reframes a common hormone disorder as a whole-body disease

A new review reframes PCOS, now proposed as PMOS, as a systemic endocrine and metabolic disorder shaped by genetic, epigenetic, ovarian, metabolic, and neuroendocrine pathways. It highlights why inconsistent diagnosis and symptom-focused care have limited progress, while targeted therapies, biomarkers, machine learning, and organ-on-chip models may support more personalized treatment.

18 Jun 2026