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Clinical trials show SGLT2 inhibitor may benefit patients with type 2 diabetes

Less than a decade ago, the Food and Drug Administration approved drugs for treating type 2 diabetes in an entirely new way.

16 Nov 2020

First-ever phase 3 advanced anal cancer trial opens for patient enrollment

The first randomized phase 3 clinical trial ever to be conducted in patients with advanced cancer of the anal canal is now open and enrolling patients.

16 Nov 2020

Antifungal agent Itraconazole inhibits SARS CoV-2 in vitro

Itraconazole is a broad-spectrum antifungal agent that has been shown to have some in vitro activity against SARS-CoV-2 by a team of Belgian and German researchers.

16 Nov 2020

Potent antiplatelet drug not superior to standard of care in reducing heart attack risk during angioplasty

The use of the more potent antiplatelet medication ticagrelor was not superior to clopidogrel in the reduction of the rate of heart attack or severe complications among people undergoing an elective procedure to open a blocked artery, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2020.

16 Nov 2020

Moderna's COVID-19 vaccine nearly 95% effective

US company Moderna have just released their early phase 3 clinical trial results for their COVID-19 vaccine which is nearly 95% effective.

16 Nov 2020

PARP inhibitor, stenoparib inhibits pre- and post-entry processes of SARS-CoV-2 in vitro

A team of researchers from the Northern Arizona University evaluated a new PARP inhibitor, stenoparib, which has recently advanced to Stage II of clinical trials to treat ovarian cancer. Their study, an initial report on in vitro stenoparib activity against human coronaviruses such as SARS-CoV-2, has been published on the preprint server bioRxiv*.

15 Nov 2020

Diabetes drug can ameliorate lives of chronic heart failure patients

Empagliflozin, a recently developed diabetes drug, can effectively treat and reverse heart failure in both diabetic and non-diabetic patients, according to researchers at the Icahn School of Medicine at Mount Sinai.

15 Nov 2020

Immunotherapy combination shrinks rare angiosarcoma tumors in 25% of patients

Researchers from SWOG Cancer Research Network, a cancer clinical trials group funded by the National Cancer Institute's Division of Cancer Diagnosis and Treatment, part of the National Institutes of Health, have shown that the immunotherapy combination of ipilimumab and nivolumab shrinks rare angiosarcoma tumors in 25 percent of all patients, with some having an even stronger response to the drug combination.

15 Nov 2020

Arthritis drug may improve COVID-19 survival among elderly patients

A type of arthritis drug may reduce the risk of dying for elderly patients with COVID-19.

15 Nov 2020

Polypill plus aspirin and polypill alone reduced cardiovascular disease risk

A single, daily pill combining blood pressure and cholesterol medications, along with the addition of a daily dose of aspirin, reduced cardiovascular disease events in people at risk for heart disease, according to late-breaking research presented today in a late-breaking clinical trial presentation at the American Heart Association's Scientific Sessions 2020.

15 Nov 2020

New medication may reduce risk for heart failure-related events in people with chronic heart failure

Omecamtiv mecarbil, a new, investigational heart medication, reduced the risk of heart failure-related events in patients with heart failure with reduced ejection fraction, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2020.

15 Nov 2020

Antidepressant may prevent worsening of COVID-19 infection, study suggests

The antidepressant fluvoxamine appears to prevent COVID-19 infections from worsening and may help keep patients out of the hospital, a trial based on research from the University of Virginia School of Medicine suggests.

15 Nov 2020

Inhaled nebulized interferon beta-1a (SNG001) helps COVID-19 patients recovers

Now, a team of researchers at the Synairgen Research, Southampton General Hospital, Southampton, United Kingdom, has found that inhaled nebulized interferon beta-1a (SNG001), a drug used for multiple sclerosis, helped COVID-19 patients have greater odds of improvement and recovery from SARS-CoV-2 infection.

15 Nov 2020

MD Anderson presents positive clinical data from combination cancer therapies at SITC 2020

Promising clinical results with combination treatments for patients with melanoma and lung cancer highlight immunotherapy advances being presented by researchers from The University of Texas MD Anderson Cancer Center at The Society for Immunotherapy of Cancer 35th Anniversary Annual Meeting & Pre-Conference Programs.

11 Nov 2020

Cabotegravir highly effective in preventing HIV among women

UNAIDS has been strongly encouraged by groundbreaking new study results showing that the antiretroviral medicine cabotegravir administered by an injection every two months – prevents HIV among women.

10 Nov 2020

Clinical study of personalized cancer vaccine to expand after promising preliminary data

A clinical trial at the University of Arizona Health Sciences designed to study the safety and effectiveness of a personalized cancer vaccine in combination with the immunotherapy drug Pembrolizumab will expand its cohort after promising preliminary data was presented at the annual meeting of the Society for the Immunotherapy of Cancer.

10 Nov 2020

Trial results show CAB LA is more effective in preventing HIV acquisition in women

The HIV Prevention Trials Network study (HPTN 084) on the safety and efficacy of the long-acting injectable antiretroviral drug cabotegravir (CAB LA), for pre-exposure prophylaxis (PrEP) in HIV-uninfected women, was stopped early by the trial Data and Safety Monitoring Board (DSMB) as results showed CAB LA to be highly effective in preventing HIV acquisition.

10 Nov 2020

Aspirin to be tested as a potential COVID-19 treatment as part of RECOVERY trial

Now, in new research, the everyday painkiller aspirin will be evaluated as a potential treatment for COVID-19 in one of the United Kingdom’s most significant trials, aiming to evaluate whether it can reduce the risk of blood clots in infected people.

9 Nov 2020

Promising yeast-expressed SARS-CoV-2 vaccine candidate effective in mice

Researchers at the Texas Children's Hospital Center for Vaccine Development, USA, have published a report on the preprint server bioRxiv that describes a yeast-expressed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor-binding domain (RBD) protein, a key target of current vaccine development efforts.

9 Nov 2020

‘A great day for science and humanity’; Pfizer’s COVID-19 vaccine is found to be 90% effective

Pfizer and BioNTech have today announced their new vaccine candidate (BNT162b2) is 90% effective against SARS-CoV-2.

9 Nov 2020

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Drug Trial News

Clinical trials show SGLT2 inhibitor may benefit patients with type 2 diabetes

First-ever phase 3 advanced anal cancer trial opens for patient enrollment

Antifungal agent Itraconazole inhibits SARS CoV-2 in vitro

Potent antiplatelet drug not superior to standard of care in reducing heart attack risk during angioplasty

Moderna's COVID-19 vaccine nearly 95% effective

PARP inhibitor, stenoparib inhibits pre- and post-entry processes of SARS-CoV-2 in vitro

Diabetes drug can ameliorate lives of chronic heart failure patients

Immunotherapy combination shrinks rare angiosarcoma tumors in 25% of patients

Arthritis drug may improve COVID-19 survival among elderly patients

Polypill plus aspirin and polypill alone reduced cardiovascular disease risk

New medication may reduce risk for heart failure-related events in people with chronic heart failure

Antidepressant may prevent worsening of COVID-19 infection, study suggests

Inhaled nebulized interferon beta-1a (SNG001) helps COVID-19 patients recovers

MD Anderson presents positive clinical data from combination cancer therapies at SITC 2020

Cabotegravir highly effective in preventing HIV among women

Clinical study of personalized cancer vaccine to expand after promising preliminary data

Trial results show CAB LA is more effective in preventing HIV acquisition in women

Aspirin to be tested as a potential COVID-19 treatment as part of RECOVERY trial

Promising yeast-expressed SARS-CoV-2 vaccine candidate effective in mice

‘A great day for science and humanity’; Pfizer’s COVID-19 vaccine is found to be 90% effective

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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